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Biomedical subjects

R Pajarre

Publications and source records attributed to R Pajarre.

6 recordsLinked to original sources
PubMed1980

Antichlamydial antibodies in chronic palmoplantar pustulosis.

Serum antichlamydial antibodies were determined with an immunofluorescence method in 40 patients affected by palmoplantar pustulosis (PPP). Antibody titre greater than or equal to 16 was found in 53% of the cases, the titre being greater than or equal to 64 in 38% of the patients. By comparison, a titre of greater than or equal to 64 was found in 13% out of 55 psoriatics, in 12% out of 41 eczema and urticaria patients, and in 3% out of 37 healthy controls. The difference between the results from the PPP patients and that of the healthy controls was statistically significant (p < 0.01). In only 8 of the 40 PPP patients was any additional evidence found of a previous venereal infection. The possibility that PPP may represent an abnormal reaction to infectious agents, e.g. Chlamydia, is discussed.

Adult↗
PubMed1979

Peroral aromatic retinoid treatment of palmoplantar pustulosis: double-blind comparison of Ro 10-9359 and placebo.

Nineteen patients with chronic, recalcitrant palmoplantar pustulosis took either placebo or aromatic retinoid ethyl ester (Ro 10-9359) during a 4-month therapeutic trial. The maximal dose of Ro 10-9359 varied between 25 and 100 mg per day, according to the individual patient's tolerance. An excellent or good therapeutic response was obtained in 6 out of 9 patients on the active medication and in 2 out of 10 patients on placebo. The difference in therapeutic response between the Ro 10-9359 group and the placebo group was statistically significant (p less than 0.05). Drying and chapping of the lips was the most common side effect of Ro 10-9359 treatment.

Adult↗