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Biomedical subjects

R Pang

Publications and source records attributed to R Pang.

22 records · Page 2Linked to original sources

Inactivation of gonococci by procaine penicillin in vivo. A pilot study.

A pilot study was carried out of 25 male volunteers with gonococcal urethritis. After intramuscular administration of 3 megaunits procaine penicillin and 1 g oral probenecid the urethral culture results for Neisseria gonorrhoeae remained positive up to five hours and thereafter became negative. These results may be useful in providing guidelines for advice on the duration of sexual abstinence following treatment. It is suggested that similar studies should be carried out in women.

Gonorrhea↗

Pavlovian fear conditioning in mice anesthetized with halothane.

Pavlovian fear conditioning was employed to investigate learning during general anesthesia. Mice were given three CS-UCS presentations while anesthetized with halothane. The CS was a 10-s tone and the UCS a 0.4-mA shock delivered intramuscularly to the hindlimbs via needle electrodes. Anesthetized control groups received either CS only, UCS only, or CS followed by a 3-min delayed UCS. Strength of fear conditioning was assessed by measuring duration of suppression of drinking induced by tone presentation in a test session conducted 24 h after training. Results showed that mice trained under anesthesia exhibited a significant amount of conditioned suppression relative to the anesthetized control groups. These results show that Pavlovian fear conditioning can occur under halothane anesthesia.

Acoustic Stimulation↗