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R Pigato

Publications and source records attributed to R Pigato.

15 recordsLinked to original sources
PubMed1992

Comparison of ST segment changes on standard and Holter electrocardiogram during exercise testing.

In order to compare the ST segment changes recorded simultaneously on Holter (Del Mar Avionics 445B recorder and DCG VII Scanner) and standard electrocardiogram, 22 patients with chest discomfort and normal resting ECG were evaluated during exercise testing. The conventional ECG was recorded using chest lead V5 and a modified lead II. The Holter recording was done using the bipolar chest lead CM5 and the same modified lead II. Bifurcating electrodes permitted simultaneous recording of electrocardiogram on both systems from the same electrode sites. Seven of the 22 patients had a positive test and 15 had a negative test by both systems. In 7 positive cases the amplitude of ST segment depression was compared. The Holter lead CM5 showed higher amplitude of ST segment depressions in 6 cases compared to the conventional lead V5: 3 cases by 0.5 mm; 2 cases by 1 mm and 1 case by 2.5 mm. In 1 case it was identical. The amplitude of ST segment depression in lead CM5 ranged from 1 to 3.5 mm (mean 2.2 +/- 0.6 mm) and in lead V5 from 1 to 2.5 mm (mean 1.5 +/- 0.6 mm). Thus the amplitude of ST depression was higher in lead CM5 by a mean of 0.7 mm compared to the lead V5. ST segment depression was present only in 6 cases in the modified lead II. ST segment depressions were reproduced faithfully in 3 patients and within the variation of 0.5 mm in other 3 cases by the Holter system.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

[Familial hypertrophic myocardiopathy: complex ventricular arrhythmias in healthy family members].

The aim of the present study was to evaluate the electrocardiographic changes among the members of a family affected by hypertrophic cardiomyopathy. Seventeen unaffected members and 8 affected members were studied by 24-hour Holter monitoring. Twenty-five normal controls were also studied by 24-hour Holter monitoring. One out of 7 (12.5%) patients with hypertrophic cardiomyopathy, 8 out of 17 (47%) unaffected relatives and 20 out of 25 (80%) controls did not show ventricular arrhythmias. One out of 7 patients (12.5%), 4 out of 17 (23.5%) unaffected relatives and 3 out of 25 (12%) of the control group showed Lown classes I-II ventricular arrhythmias. Complex ventricular arrhythmias (III-V Lown classes) were detected in 5/7 (71.4%) of patients, in 5/17 (29.5%) of unaffected members and only in 2/25 (8%) of the normals. Among the unaffected members we compared the prevalence of complex ventricular arrhythmias between the offspring of patients with that of the unaffected first-grade relatives. Three out 7 (43%) of the offspring of the patients showed complex ventricular arrhythmias and none among the offspring of normal first-grade relatives showed such arrhythmias. Neither the patients nor their relatives in this study showed any significant ST segment changes during the 24-hour Holter monitoring. We suggest that in first-grade relatives of patients with familial hypertrophic cardiomyopathy, complex ventricular arrhythmias could be a marker of latent disease, without clinical and echocardiographic manifestations.

Adolescent↗
PubMed1990

[Stroke: Holter monitoring in 15 hypertensive patients].

The objective of the study is to evaluate the prevalence of ventricular arrhythmias during acute stroke in hypertensive patients: 15 hypertensive patients (9 males and 6 females; mean age 56 +/- 5) without clinical and electrocardiographic evidence of organic heart disease underwent 24 hour Holter monitoring during acute stroke. Another group of 15 uncomplicated hypertensive patients (14 males and 1 female, mean age 49 +/- 5) without clinical and electrocardiographic evidence of organic heart disease underwent 24 hours Holter monitoring as controls. The Holter monitoring was repeated in 8 patients who survived during follow-up, after a mean period of 15 months: 13/15 (86%) patients with acute stroke had ventricular arrhythmias against the 7/15 (47%) in the control group. Moreover 9/15 (60%) of patients with stroke had complex ventricular arrhythmias against the 3/15 (20%) in the control group; 6/8 patients who survived stroke, during follow-up showed complex ventricular arrhythmias but the degree of severity was lower when compared to the acute phase; 9 patients during acute stroke showed episodes of prolongation of QTc interval during Holter monitoring. The systolic blood pressure was found generally higher during the acute phase of stroke than before. Our results show higher prevalence of ventricular arrhythmias especially of the complex forms during acute stroke in hypertensive patients.

Adult↗
PubMed1988

[Distributions, mean values and correlations of various coronary risk factors in a population of Veneto].

During the National Research Council (CNR) program called Atherosclerosis-Risk Factors 2 (ATS-RF2) a random sample of 1903 subjects (50.1% male) aged 20-59 years was examined in the general population of Mirano-Venice. Mean values of serum total cholesterol and triglycerides, body mass index, as well as systolic and diastolic blood pressure were assessed. On the whole these turned out to be higher in men and increased with age. The continuously distributed variables showed an approximately normal distribution and a close correlation. Comparing our results with those obtained by other Italian units co-operating in the same CNR program, different levels of serum total cholesterol and systolic blood pressure were observed. The overall risk factor pattern in northern Italian regions is closer to that reported in the literature for central European countries than to that of southern Italian regions. These findings might explain why mortality due to ischaemic heart disease is higher in northern Italy and becomes progressively smaller in central and southern Italy.

Adult↗
PubMed1987

[Prevalence, characteristics and clinical correlates of left ventricular hypertrophy in stable hypertension. Echocardiographic study].

251 in stable hypertensives were studied with M-Mode and two-dimensional echocardiography, in order to evaluate the prevalence of left ventricular hypertrophy (LVH), its patterns and clinical correlates. 54 subjects (21%) had been treated previously with antihypertensive drugs while the remaining 197 (79%) had not. A normal left ventricle was found in 69 subjects (27.1%; group A); a concentric LVH (h/r greater than or equal to 0.45) was found in 99 (39.4%; group B), while an eccentric LVH (left ventricular myocardial mass index greater than 140 g/m2, h/r less than 0.45) in 83 (43.1%; group C). An asymmetric LVH (septum to posterior wall thickness ratio greater than or equal to 1.3) was found in 33 subjects (3 did not fulfill the criteria for LVH, 21 had a concentric, and 10 an eccentric LVH). Mean age was significantly higher in group B as compared to groups A and C. The body mass index was comparable in all groups. Mean systolic blood pressure was significantly higher in groups B and C as compared to A. The duration and the severity of hypertension did not differ among the three groups. W.H.O. stage III was absent in group A, but no differences were found between group B and C as for W.H.O. stage distribution. We conclude that such factors as BMI, duration and severity of hypertension poorly correlate with the occurrence of LVH and its patterns. The fact that group B hypertensives were older than the others on average is against the hypothesis that eccentric hypertrophy follows the concentric pattern. Whether these two patterns represent separate entities in relation to different hemodynamic profiles deserves further investigation.

Adult↗
PubMed1978

Clinical experiences with methyldopa.

1. The hypotensive effect of methyldopa alone or associated with other hypotensive drugs was evaluated in 155 patients. After 10 days of treatment, the blood pressure was back to normal in 80% and in 50% of the patients with mild and moderate hypertension, and it was significantly decreased in those with severe hypertension. 2. Contrary to other hypotensive drugs, it did not produce a significant increase in BUN and serum creatinine. Occasional or recurrent episodes of orthostatic hypotension were observed in about 18% of the cases, but in none did it produce important symptoms of cerebral or myocardial ischaemia.

Blood Pressure↗
PubMed1978

[Screening of hypertension in a community. Data from the "Camposampiero Project" (author's transl)].

During the initial phase of the international "Community Control Programme of Hypertension" sponsored by W.H.O., and carried out in Italy by the Clinica Medica II of the University of Padua, a random sample of 5852 subjects was screened (11% of the whole population). The response rate was of 75.3%; the prevalence rate of hypertension (160 or 95), based on casual blood pressure readings, was 29.5%. Measures of the control of hypertension and other relevant results are: a 35.6% of all hypertensives were aware of their condition, and of these 41% were under treatment. Effective treatment of hypertension was seen in one 12.3% of all treated hypertensives (values lower than 16/95), while 14.2% of all hypertensives had values at or above 200 (systolic) or 120 (diastolic). 98.2% of all hypertensives were not under effective control. As a whole, control of hypertension was better in women and in elderly patients.

Adult↗
PubMed1977

[The orthostatic hypotension in patients treated with antihypertensive drugs (author's transl)].

Occasional or recurrent episodes of orthostatic hypotension were observed in 58 out of 584 hypertensive patients treated with alpha-methyldopa, beta-blockers and clonidine alone or associated with diuretics and/or hydralazine and/or reserpine. They occurred more frequently in the elderly. In none dicardial ischaemia. In only 3 cases it caused drowsiness and in 2 transient T wave inversion. These results suggest that postural hypotension does not contraindicate the continuation of antihypertensive treatment.

Adrenergic beta-Antagonists↗
PubMed1976

Blood pressure and its spontaneous variations in a northern Italian population.

1. Blood pressure has been measured in a random sample of 5852 subjects (both sexes, 20-64 years old). The prevalence of hypertension (blood pressure greater than or equal to 160 mmHg and/or 95 mmHg; 150 mmHg and/or 90 mmHg under the age of 30 years) was 29-5%. 2. In a cohort of 972 detected hypertensive subjects, longitudinal changes (2 and 5 months after the initial examination) were evaluated. The phenomenon of regression toward the mean value was evident. 3. The implications of the variability of blood pressure in a community control programme of hypertension are discussed.

Adult↗