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R Pisani

Publications and source records attributed to R Pisani.

At least 37 records · Page 2Linked to original sources
PubMed1991

[Endoscopic surgery of the digestive system: state of the art. Opinion of an endoscopic surgeon].

The Authors review the possible applications of surgical endoscopy in oesophageal, gastric, biliary, pancreatic and colic diseases. This critical assessment, performed under the abdominal endoscopic surgeon's point of view, is based on the overall experience of about 20 years of surgery, with particular regard to the sclerosis of oesophageal varices, neoplastic obstructions of oesophagus, biliary tract, colon and localized Laser treatment of neoplasms. Based on the results achieved, thanks to selective indications and monitoring by conventional surgical experience, the Authors conclude by staging a better reliability of the surgeon who performs surgical endoscopy to obtain good results after an accurate selection of those cases which can really benefit from endoscopic management.

Attitude of Health Personnel↗
PubMed1990

Comparison of the antiviral activity and toxicity of a protein magnesium ammonium phospholinoleate anhydride polymer with other antiviral drugs.

1. SB-73, a magnesium ammonium phospholinoleate anhydride aggregate, exhibited antiviral action in vitro in the concentration range of 50 to 100 micrograms/ml against herpes simplex type 1, stomatitis vesicular virus, adenovirus type 5, and in vivo in the dose range of 0.7 to 1.3 mg/kg against canine parvovirus and distemper virus. 2. The lethal dose (LD50) was 2.71 +/- 1.55 g/kg body weight in mice inoculated intraperitoneally. Oral ingestion of the aggregate up to 30 g/kg body weight by mice had no lethal effects during the 14 days of observation. 3. In in vitro cytotoxicity experiments with fibroblasts (V-79 Chinese hamster cell line), no toxic effects were observed with SB-73 concentrations (120 micrograms/ml) having antiviral activity. 4. In a cellular proliferation experiment using hamster V-79 cells, we observed 72% proliferation after treatment of the cells with a high concentration (500 micrograms/ml) of SB-73. 5. Compound SB-73 showed no genotoxicity for human lymphocytes at concentrations of 100 micrograms/ml. 6. When the cytotoxicity and genotoxicity of SB-73 were compared with those of acyclovir, idoxuridine and AZT at 500 micrograms/ml concentrations the compound was found to have effects similar to those of acyclovir.

Acyclovir↗
PubMed1990

[Endoscopic papillotomy today. Indications and results].

The therapeutic possibilities offered by endoscopic papillotomy have improved in comparison with the recent past by virtue of mounting experience and increasingly satisfactory results. The position of the surgeon in the face of this procedure is more serene and objective than those who concern themselves with the endoscopic method as such. In long-term personal experience, endoscopic papillotomy was indicated in 162 cases of biliary lithiasic pathology--associated and otherwise with Odditis--and angiocolitis, with and without the gall-bladder. The reference to endoscopic treatment was mainly confined to patients with associated pathologies, dependent and otherwise, that involved general or specific surgical risk, while evaluations of the lumen of the biliary excretory way, of the coexistence of more or less incisive biliary inflammation, of the age of the patient--all parameters to which are attributed special importance for the choice between derivative intervention and open papillotomy--do not possess particular significance for the endoscopic method. Results obtained and the low incidence of short and long-term morbility support the claim to absolute usefulness of the method when it is proposed on correct indications and carried out with expert technique.

Ampulla of Vater↗
PubMed1987

Calcification and ossification of the spinal arachnoid after intrathecal administration of Depo-Medrol.

A woman 38-year-old, suffering for about ten years from multiple sclerosis and treated with repeated therapy cycles of intrathecal Depo-Medrol, developed a spastic paraparesis at the lower limbs. A lumbar myelography was carried out, and a dorsal block was demonstrated. The patient underwent a dorsal laminectomy, and arachnoidal calcification and ossification was find, but the removal of the bone plaques was ineffectual in order to the subsequent course of the neurological troubles. The results of the histological study and chemical tests are reported, and the etiology and the pathogenesis are discussed on the basis of the pertinent literature.

Adult↗
PubMed1985

Hematomyelia during anticoagulant therapy.

An unusual case of hematomyelia during anticoagulant therapy is reported in a patient after cardiac surgery. A review of the pertinent literature is presented. After medical and surgical treatment, the transverse symptoms largely subsided with rehabilitation of the patient.

Hemorrhage↗
PubMedDate not supplied

Hemodynamic and humoral interactions between captopril and nifedipine.

Nine patients with uncomplicated essential hypertension received, according to a randomized sequence, captopril (25 mg three times daily), nifedipine (10 mg three times daily), and both drugs for 1 week, with each treatment period separated by a 1-week interval during which a placebo was given. Captopril significantly reduced blood pressure and plasma aldosterone, increased plasma renin activity (PRA), and did not change heart rate. Nifedipine exerted a similar effect on blood pressure and PRA, but it increased heart rate and did not change aldosterone. Captopril plus nifedipine further reduced blood pressure and increased PRA, did not change heart rate, and reduced aldosterone to values similar to those after captopril alone. The hypotensive effect of captopril was highly predictable by basal PRA values, and that of nifedipine by age, while PRA increments induced by captopril were unrelated to those induced by nifedipine. These data indicate that: 1) captopril and nifedipine exert an additive effect on blood pressure and renin; 2) captopril counteracts the heart rate increase induced by nifedipine; 3) nifedipine does not influence the aldosterone inhibition induced by captopril. It is suggested that the association of the two drugs can be usefully employed in the treatment of hypertension.

Adult↗
PubMedDate not supplied

Long-term survival of a patient with a giant-cell tumor of the sphenoid body: a case report.

Giant-cell tumors (osteoclastomas) of the sphenoid body are rare, histologically benign lesions that can grow in different directions within the bony structures of the skull base. To date, the precise role of the different surgical strategies (radical versus partial resection; biopsy) and of supplementary postoperative radiotherapy remains undefined due to the short follow-up of the majority of the reported cases. We present a patient who is alive without symptoms or signs of recurrence 44 years after a macroscopically radical excision of the neoplasm followed by radiotherapy.

Adult↗
PubMedDate not supplied

[Criteria of diagnostic evaluation and results of surgical treatment in chronic pancreatitis].

Correct diagnostic evaluation of chronic pancreatitis pictures must of necessity be directed to recognition of recurrent and stable forms and identification of the pathogenetic cause of the clinical forms. This objective seems to be achieved more than satisfactions by the diagnostic protocol employed personally, the first stages of which include X-ray of the abdomen for the identification of possible pancreatic calcification, ultrasonography and computed axial tomography for the analysis of organ's morphology and structure, intestinal absorption and pharmacodynamic tests of the papillary excretory complex for the evaluation of functional state of the pancreas. At a second time, this diagnostic protocol includes endoscopic pancreatography for the analysis of the excretory duct and identification of possible calcareous concretions in its lumen, and district angiography, for information on the extreme viscero-vascular implications and the possibility of coexistence of district portal hypertension pictures. The resulting information dominates therapeutic choices by indicating the usefulness of performing a papillo-sphincteroplasty to handle the biliary aetiology in recurrent forms and Wirsung septoplasty for ductal ostial stenoses. The choice of shunts and resections is confirmed to the stable forms, with the use of the former in the event of ductal dilatation and of the latter in the absence of this and in the presence of more or less marked gland fibrosis. Derivative procedures also control treatment of chronic post-pancreatitis pseudocyst, with a clear-cut prevalence of cysto-gastric shunts over all the other possibilities.(ABSTRACT TRUNCATED AT 250 WORDS)

Acute Disease↗