Biomedical subjects

R Plotzker

Publications and source records attributed to R Plotzker.

4 recordsLinked to original sources

PubMed1990

Life-threatening thyrotoxicosis.

For most critically ill hyperthyroid patients with suspected thyroid storm, treatment should begin before laboratory confirmation is received. A combination of therapies directed at the thyroid gland (thionamides, iodides) and at limiting cellular response (beta-blockers, corticosteroids) are usually successfully employed. The goal of emergency therapy remains one of stabilization. Management of thyroid crisis is not complete until ablative therapy (radioactive iodine or surgery) is performed to prevent a recurrence.

Adult↗

PubMed1976

Gastritis, duodenitis, and bleeding duodenal ulcer following mefenamic acid therapy.

A 46-year-old woman developed hematemesis and melena two weeks after starting mefenamic acid therapy for osteoarthritis of the spine. Esophagogastroduodenoscopy, arteriography, and a laparotomy revealed antral gastritis, duodenitis, and an acute bleeding ulcer in the third portion of the duodenum. Although mefenamic acid has many of the pharmacologic and physicochemical properties of aspirin and produces gastrointestinal ulceration in animals when administered in large doses, the English literature reveals only one case of gastric ulceration and a single instance of upper-gastrointestinal tract hemorrhage associated with its use. This case warns that mefenamic acid may cause serious gastric and duodenal inflammation and ulceration more commonly than is presently suspected.

Duodenal Diseases↗

PubMed1975

Ineffectiveness of hemodialysis in copper sulphate poisoning.

A fatal case of severe copper sulphate poisoning is reported in whom hemodialysis was performed 13 h after ingestion. At autopsy a significant amount of copper was found in the brain, heart, liver, kidney, spleen and adrenals. This case indicates sopper is nondialysable and that hemodialysis is ineffective in the treatment of acute copper sulphate poisoning.

Acute Kidney Injury↗

PubMedDate not supplied

Case report. Amanita virosa acute hepatic necrosis: treatment with thioctic acid.

A 55-year-old woman suffered acute hepatic necorsis following ingestion of Amanita virosa mushrooms. Successful treatment included the use of thioctic acid. A discussion of Amanita poisoning an the therapeutic modalities available is presented.

Amanita↗