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Biomedical subjects

R Porto

Publications and source records attributed to R Porto.

17 recordsLinked to original sources

[Nutritional status of vitamin D in mothers and neonates of Ushuaia and Buenos Aires].

Serum levels of calcium, phosphorus, total alkaline phosphatase (AP) and 25 hydroxyvitamin D (250HD) were measured at the end of the winter in Group 1 (Ushuaia, latitude 55 degrees S): 16 women (24-48 hs postpartum serum blood) and 20 neonates (cord blood) and in Group 2 (Buenos Aires, latitude 34 degrees S) 21 women (24-48 hs postpartum serum blood) and their 21 neonates (cord blood). The neonatal serum calcium and phosphorus were higher and the neonatal serum AP and 250HD level were lower than maternal levels in both groups (Table 1 and 2). Serum levels of 250HD were diminished (< 8 ng/ml) in 62% of the mothers and 81% of the neonates of Ushuaia and in 24% of the mothers and 16% of the neonates of Buenos Aires (figure 1). Neonatal serum 250HD levels correlate with maternal serum 250HD levels in the paired group of Buenos Aires (r = 0.65, p < 0.003) (Figure 2). In Ushuaia the serum 250HD levels (X +/- SD) in neonates (3.9 +/- 2.7 ng/ml) and in mothers (6.3 +/- 4.8 ng/ml) were lower than in Buenos Aires (neonates: 11.3 +/- 6.0 ng/ml and mothers: 14.4 +/- 8.4 ng/ml, p < 0.001). Maternal serum calcium levels were lower in Ushuaia (8.7 +/- 0.8 mg/dl) than in Buenos Aires (9.2 +/- 0.4 mg/dl) (p < 0.05). In conclusion, 1) In Ushuaia pregnant women and their neonates had a deficient nutritional state of vitamin D. Preventive administration of vitamin D would probably be beneficial.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Disseminated Klebsiella rhinoscleromatis infection.

A 35-year-old obese black American woman presented with nausea, vomiting, diarrhea, fever, cough, and chest pain of 2 weeks duration. She was pancytopenic and acidotic, with respiratory failure and hypotension. A diagnosis of septic shock was made, and the patient died 48 hours after admission. Blood cultures were positive for organisms that were reported to be Klebsiella rhinoscleromatis. At autopsy she had massive hepatic necrosis with numerous Mikulicz's cells. The lungs, spleen, and bone marrow were also involved. To our knowledge, this is the first report of a case of systemic infection with K rhinoscleromatis.

Adult↗

Dermatopathic lymphadenitis. The spectrum and significance of its morphologic features.

The lymph nodes from 50 axillary node dissections were evaluated by light microscopy and immunohistochemistry for the presence of dermatopathic lymphadenitis-like histologic features. On the basis of hematoxylin-eosin-stained sections alone, a histologic continuum was observed ranging from minimal paracortical changes to fully developed dermatopathic lymphadenitis. Twenty-three lymph node biopsies previously interpreted as diagnostic of dermatopathic lymphadenitis were reviewed. Only nine of these showed the fully developed dermatopathic lymphadenitis. Only one of these patients had a dermatitis. Our conclusions are that the presence of dermatopathic lymphadenitis does not mean that the patient has concomitant skin disease, and that axillary lymph nodes from patients without skin disease manifest a spectrum of dermatopathic lymphadenitis-like histologic features. Dermatopathic lymphadenitis may represent one end of a normally occurring histologic spectrum that may be found in the absence of a dermatitis.

Acquired Immunodeficiency Syndrome↗

[The periodic hypersomnia and megaphagia syndrome in a young female, correlated with menstrual cycle (author's transl)].

A 21-year-old female was first seen in 1974 for periodic hypersomnia. It had started at 13 years of age and was characterized by 4-6 days of drowsiness with megaphagia and some light psychic disorders. The attacks usually occurred at approximately 5-6 days after menstruation. Later, after an interval of oral contraception, they appeared during ovulation and increased in duration. During the periods of contraception, these attacks disappeared completely. At present (1980), the episodes are characterized by periodic hypersomnia, seen in a nocturnal polygraphic study; megaphagia has decreased, but the patient appears uncommunicative, sub-active and inexpressive when awaking in the course of the periods of somnolence. Several EEG recordings were made between 1974 and 1980, which showed few or no abnormalities during the attacks and which were normal with in the inter-ictal periods. Hormonal investigations failed to show any striking abnormality or correlation with continuous polygraphic studies. Similarity of this syndrome with the 'periodic hypersomnia and megaphagia in adolescent males' syndrome (Kleine-Levin) is discussed.

Adult↗