Toward longitudinal conceptions of psychiatric disorder.
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Biomedical subjects
Publications and source records attributed to R R Lewine.
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The choice of comparison groups in the study of schizophrenic subtypes is discussed. Current research rests upon the comparison of schizophrenic subtypes and controls unselected for the subtype characteristics used to divide the schizophrenics. One cannot infer, on the basis of this type of group comparison, whether subtype differences are specific to schizophrenia or reflect general personality and behavioral characteristics. It is suggested, therefore, that control groups be selected for their comparability to the schizophrenics on subtype characteristics.
Teachers' comments in the childhood school records (grades K-12) of 143 psychiatric patients and their matched controls were coded along 23 bipolar dimensions. Two methods of grouping these scales were compared: rational clusters and factor analysis. Factor analysis yielded more numerous and narrowly defined behavioural groupings. Schizophrenics, personality disorder patients, neurotics, and depressives were compared to their matched controls on each of the cluster and factor scores. Both schizophrenics and personality disordered patients were significantly less agreeable in childhood than their respective controls. Pre-schizophrenics also were significantly more unstable. Depressives were more independent than their controls, while neurotics did not differ significantly in any respect from normals in childhood. The data suggest that schizophrenia may have specific developmental patterns of possible aetiological or early diagnostic significance.
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