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Biomedical subjects

R R Mohler

Publications and source records attributed to R R Mohler.

3 recordsLinked to original sources

Immunology and disease control: a systems approach.

The application of system theory (or more precisely, differential equations) to immunology and disease, in general, is presented here. Particular results from U.S.-Russian research collaboration depict the potential role of such systematic analysis for more effective health care and disease control. In particular, some emphasis is given to control of influenza. After a brief systematic overview of immunology, a simple infectious disease model is developed to explain four basic forms of disease: subclinical, acute, lethal and chronic. Then, disease treatment is studied.

Acute Disease↗

Distribution models of recirculating lymphocytes.

Linear time-invariant, linear time-variant, and linear time-delay models are compared to a more accurate nonlinear model for the distribution of recirculating lymphocytes to various relevant organs of the immune process. The models are based on various degrees of approximation to the complex non-Newtonian tubile flow and tissue diffusion phenomena.

Animals↗