PubMed Health⌕ Search

Biomedical subjects

R R Rickert

Publications and source records attributed to R R Rickert.

At least 37 records · Page 2Linked to original sources
PubMed1986

Septal panniculitis as a manifestation of Lyme disease.

A 22-year-old woman presented with fever, chills, photophobia, and headaches, followed by a centrally clearing erythematous skin eruption, migratory polyarthralgias, conjunctivitis, and subsequently, tender, nodular skin lesions. Antibodies to Borrelia burgdorferi were consistent with acute Lyme disease. Skin biopsy revealed acute septal panniculitis. This dermatologic manifestation has not been previously described in Lyme disease.

Adipose Tissue↗
PubMed1986

Quality assurance in anatomic pathology.

Comprehensive quality assurance in anatomic pathology must address several levels of laboratory operation: procedural/technical issues, the quality of the diagnostic report, and the medical consultative role of the pathologist. Procedural/technical quality control in anatomic pathology differs very little from that practiced in the various sections of clinical pathology. Assessment of the quality of the final report is a major responsibility of the pathologist who renders the diagnosis. Guidelines that systematically address such issues as specimen handling and the content of the diagnostic report are effective in promoting consistency, completeness, and the clinical relevance of the information provided. Quality assessment of the pathologist's consultative role is more difficult to define and implement. However, systematic evaluation and correlative review of all available diagnostic information, appropriate use of consultation and case review, and participation in continuing education and self-assessment activities all may contribute to and help document the quality of services provided. It is important to emphasize the value of flexibility in designing a comprehensive quality assurance program for anatomic pathology. Departments differ markedly in characteristics such as staff size, subspecialty interests, teaching commitments, and volume and type of case material. Nevertheless, the general principles of written organization, systematic monitoring, and documentation of adherence to the program should be followed. Just as the design of the program may benefit from flexibility, the laboratory should be prepared to modify its quality control and assurance techniques and implement corrective measures should surveillance identify problems such as frequent typographic errors, inadequate diagnostic information, or deterioration in correlation between frozen section and final diagnoses. The ultimate objective of all of these efforts is to provide the referring physician with an accurate, clinically relevant diagnostic report, thereby enhancing the pathologist's role as a valued medical consultant.

Pathology, Clinical↗
PubMed1984

The important "impostors" in the differential diagnosis of inflammatory bowel disease.

When evaluating patients suspected to have inflammatory bowel disease, we generally focus on the important differential features which distinguish ulcerative colitis from Crohn's disease. A distinction between them is possible in 80-90% of cases when accepted clinical, radiographic, and pathologic criteria are applied. The remaining idiopathic cases are usually classified as colitis, indeterminate type. In this presentation, major attention will also be directed to a variety of other disorders which may masquerade as idiopathic inflammatory bowel disease. The pathologic features to be described which serve to identify these "impostors" will emphasize appearances in biopsy material.

Anti-Bacterial Agents↗
PubMed1982

Familial juvenile polyposis coli. A clinical and pathologic study of a large kindred.

A kindred with familial juvenile polyposis coli is described. Of 92 family members, 26 have had symptoms consistent with polyposis, and a definite diagnosis of polyposis has been made in 19. Two family members have developed colorectal carcinoma before age 40 yr. The lesion of juvenile polyposis is a characteristic nonneoplastic polyp that is distinct from the neoplastic lesion of adenomatous polyposis. Patients with this disorder develop symptoms at an earlier age than those with adenomatous polyposis. Both variants of polyposis appear to have a dominant pattern of inheritance. Patients with juvenile polyposis who present in infancy are likely to have severe symptoms and complications. Although the premalignant potential of the juvenile polyp remains in doubt, there may be an increase risk of gastrointestinal cancer in these patients and their families.

Adolescent↗
PubMed1981

Simultaneous occurrence of renal cell adenocarcinoma and urothelial carcinoma of the renal pelvis in the same kidney diagnosed by preoperative angiography.

An unusual case of dissimilar histologic neoplasms in the same kidney is presented. An 86-year-old man had renal cell carcinoma and urothelial carcinoma in the same kidney eight years after therapy for urinary bladder carcinoma. These two different types of neoplasms were identified preoperatively by angiography. A peculiar hamartoma was also found in the same kidney.

Adenocarcinoma↗
PubMed1981

Indurative mastopathy: a benign sclerosing lesion of breast with elastosis which may simulate carcinoma.

Five cases of a benign sclerosing lesion of breast are described. The lesion is characterized by a stellate, indurated zone of sclerosis and elastosis in a region of benign ductal proliferation. Because of the stellate configuration and frequently retracted cut surface, the lesion may grossly resemble scirrhous carcinoma. Microscopically, there is often entrapment of benign but distorted ducts at the sclerotic margin, which may further cause confusion with cancer. Of special interest is the radiographic appearance, which may be indistinguishable from scirrhous carcinoma. The term "indurative mastopathy" is a descriptively valid designation for these lesions.

Adenocarcinoma, Scirrhous↗
PubMed1981

Hyperplastic Gastropathy. Analysis of 50 selected cases from 1955-1980.

Hyperplastic gastropathy remains a rare condition. Fifty cases of hyperplastic gastropathy (adhering to rigid pathologic and clinical criteria) were analyzed from the English literature for the past 25 years. This was compared to a similar review of 50 cases published 25 years ago. A clearer pathologic classification-mucous cell hyperplasia, glandular cell hyperplasia and mixed mucous-glandular cell hyperplasia is recommended. The etiology and pathogenesis remain obscure. The clinical characteristics and medical and surgical therapy are discussed. The course appears uncertain as does the relationship to gastric carcinoma.

Adolescent↗
PubMed1980

Intraductal papilloma arising in supernumerary vulvar breast tissue.

A case of intraductal papilloma arising in ectopic vulvar breast tissue is described. This is believed to be the first example of this lesion reported in the literature. The general clinical and pathologic features of supernumerary vulvar breast tissue, and the various breast diseases occurring at this ectopic site, are reviewed.

Adult↗
PubMed1980

The "early" ulcerative lesion of Crohn's disease: correlative light- and scanning electron-microscopic studies.

Submucosal edema and lymphectasia have traditionally been considered the earliest recognizable alterations in Crohn's disease. However, a characteristic pattern of ulceration grossly resembling the oral lesions of aphthous stomatitis is believed by others to be the earliest macroscopic lesion. We have studied 50 consecutively accessioned surgical specimens with Crohn's disease in an effort to define more thoroughly the frequency, distribution, and morphology of these "aphthoid" ulcers. The scanning electron microscope (SEM) was used in the study because an understanding of the morphology and evolution of these lesions requires an appreciation of their three-dimensional configuration. Typical "aphthoid" ulcers were identified in 35 of the 50 specimens studied. Grossly the typical ulcerative lesion varies from barely visible up to 3 mm in diameter. They have a characteristic light-microscopic appearance consisting of focal ulceration usually overlying an aggregate of lymphoid tissue. The SEM was helpful in identifying the smallest of these lesions and was especially useful in defining a variety of villous abnormalities in the small bowel mucosa adjacent to the ulcers.

Adolescent↗
PubMed1979

Adenomatous lesions of the large bowel: an autopsy survey.

A comprehensive autopsy survey of the large bowel showed that adenomas were very common lesions occurring in about one-half of the 518 cases studied. The great majority were small adenomatous polyps (tubular adenomas), 86.7% measuring less than 10 mm in diameter. Adenomas with a more complex tubulovillous pattern were larger with a mean diameter of 19.0 mm. There was no apparent incresae in mean size of adenomas with age. Nineteen clinically unsuspected cancers were discovered. Fourteen (8 in situ and 6 invasive) cancers had areas of residual benign adenoma. Five invasive cancers had no residual benign component. No in situ carcinomas or small (less than 10 mm) invasive cancers not containing residual adenoma were found. The results suggest that, although adenomas of the large bowel are very common, the vast majority are simple adenomatous polyps which do not undergo progressive growth and malignant change. Conversely, it appears that cancers may arise from benign adenomas which have the characteristics of large size and a more complex villous architecture.

Adenoma↗
PubMed1979

The outlook after total colectomy in patients with Crohn's colitis and ulcerative colitis.

The postoperative recurrence rates for Crohn's colitis (CC) and ulcerative colitis (UC) have varied markedly in different medical centers. We have reviewed the reasons for this variation and present our own series of patients in a manner which allows comparison with previous studies. In our study: 1) Patients with CC had an overall recurrence rate of 38% after total colectomy. By actuarial statistics, this recurrence rate computes to 48% by 12 years after operation. 2) Patients with ileal disease, even if totally removed at operation, had a recurrence rate of 48% whereas those with no obvious ileal involvement had a recurrence rate of 18%. 3) When nonspecific criteria are used for recurrence, which we call "complication," as has been the case in several previous studies of CC, even patients with UC had a complication rate of 33%. Such complications both in UC and CC represent postoperative occurrence rather than ileal recurrence of the inflammatory process. 4) Patients with CC develop more postoperative complications than patients with UC, but for most of the time they were asymptomatic. In this series there were no patients with disease originally or almost entirely limited to the colon who became "intestinal cripples" as a result of recurrent disease. 5) Patients with short preoperative intervals had the highest recurrence rate, whereas patients with disease of the terminal ileum had the highest postoperative complication rate. 6) Patients with "superficial" CC had a low recurrence rate, probably because of a shorter follow-up than the other patients. There were no true recurrences in patients with UC.

Adult↗
PubMed1979

Video intercom: O.R. consultation and frozen section with screen display of gross and microscopic findings.

Seldom does the pathologist at Saint Barnabas Medical Center, Livingston, NJ, enter the operating room to consult with the operating surgeon. Instead, consultation takes place via an audio-intercommunication system supplemented by video. In this article, the authors explain how and when the system is used, the equipment needed, and the benefits to be derived by pathology residents.

Education, Medical↗
PubMed1979

Granular cell tumor of the common bile duct. Case report and review of literature.

A case of granular cell tumor is reported and the main features of the previously reported cases are summarized. This lesion usually presents in a black woman as a small tumor obstructing the common bile duct and resulting in cholecystitis and/or obstructive jaundice. The cell of origin is still disputed. Local resection with cholecystectomy and choledochoduodenostomy appears to be the treatment of choice.

Bile Duct Neoplasms↗
PubMed1978

Granular-cell tumors (myoblastomas) of the anal region.

Three cases of granular-cell tumor of the perianal region are reported. The clinical and pathologic features of these tumors are reviewed. Their precise histogenesis remains uncertain. The association with pseudoepitheliomatous hyperplasia of the overlying epithelium, which was well illustrated in two of the three cases, is discussed. The lesions are nearly always benign, and the treatment of choice is local excision.

Adult↗
PubMed1977

Diagnosis of a bleeding Meckel's diverticulum using radiopertechnetate.

A case report of bleeding from a Meckel's diverticulum diagnosed by Tc99-m pertechnetate scanning is presented. The noninvasive advantage of this method justifies its early use as a diagnostic measure when a Meckel's diverticulum is suspected in the differential diagnosis of lower gastrointestinal bleeding.

Adult↗