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Biomedical subjects

R Rönnerstam

Publications and source records attributed to R Rönnerstam.

10 recordsLinked to original sources
PubMed1986

Persistence of Serratia marcescens, Serratia liquefaciens and E. coli in solutions for contact lenses.

Twenty-four different brands of contact lens solutions were experimentally inoculated with strains of S. marcescens, S. liquefaciens and E. coli. Only flexol and hexidin could sufficiently suppress the growth of Serratia strains. If a soaking agent is to be effective in suppressing S. marcescens it must have a chlorhexidine concentration of at least 50 micrograms/ml and a thiomersal concentration of 10 micrograms/ml.

Chlorhexidine↗
PubMed1986

Neonatal chlamydial conjunctivitis.

Maternal chlamydial antibodies were determined in cord sera of 41 infants who developed neonatal chlamydial conjunctivitis and compared with the antibody profile of infants who had been exposed to Chlamydia trachomatis at birth by their isolation positive mothers but in whom conjunctivitis did not develop. No protective effect could be attributed to maternal antibodies transferred to the infants. Paired sera samples were collected from 18 infants with chlamydial conjunctivitis. Chlamydial IgM antibodies were detected in four of these 18 cases at the time diagnosis was established by isolation. An additional eight cases had developed chlamydial IgM at the time the convalescent sera samples were taken, on average on day 40. At that time symptoms had disappeared after systemic treatment had been given. Thus chlamydial IgM antibodies were eventually shown in two thirds of infants with chlamydial conjunctivitis who were all systemically treated and clinically healed. These data suggest a cautious assessment of chlamydial IgM in the diagnosis of chlamydial pneumonia.

Adult↗
PubMed1985

Prevalence of chlamydial eye infection in patients attending an eye clinic, a VD clinic, and in healthy persons.

Chlamydial eye infection was detected in 28 of 983 ophthalmological patients with conjunctivitis or keratoconjunctivitis, with a peak frequency of over 9% in patients aged 16-20 years and with decreasing frequency thereafter. In patients aged 1 to 15 years chlamydial conjunctivitis was not observed. Chlamydial eye infection could not be detected in patients at a venereal diseases clinic, though chlamydial genital infection was rather frequent in these patients. Nor was Chlamydia trachomatis found in the eyes of healthy young adults. In patients with proved chlamydial conjunctivitis unilateral symptoms were the rule. Pseudoptosis was the most conspicuous presentation in two cases. A prolonged course can be expected in chlamydial eye infection if the condition is unrecognised and effective treatment delayed. The venereal background of the condition must also influence the management.

Adolescent↗
PubMed1983

Neonatal chlamydial eye infection: an epidemiological and clinical study.

Neonatal chlamydial eye infection was detected in 39 cases of 281 infants with purulent conjunctivitis seen at the Department of Ophthalmology. Most cases of neonatal chlamydial eye infection (90%) were detected during the first month of life, and no case was found after 2 months of age. C. trachomatis was not isolated from any of 161 healthy control infants at 3-4 weeks of age. Genital chlamydial infection was demonstrated in 50% of the mothers to infected infants. Two of these women developed post-partum complications possibly due to chlamydial infection. Mothers of infected infants tended to be younger than average. Of 23 cases examined 2 years later, late sequelae were identified in 3.

Adolescent↗
PubMed1982

Chlamydial eye infection in adults.

In Western industrialized countries, conjunctivitis caused by Chlamydia trachomatis is most prevalent in adults at about the age of 20 years. In the case of classical trachoma in developing countries, the highest incidence of active disease occurs in children between 2 and 5 years of age. Inclusion conjunctivitis in adults is usually an autoinfection, resulting from a concomitant genital chlamydial infection. By contrast, in endemic trachoma the infection is spread from eye to eye. Only rarely has a nongenital transmission of inclusion conjunctivitis been inferred, among medical personnel and after swimming-pool bathing. Neonates with inclusion blennorrhea also may transmit the infection to family members. Diagnosis relies on the demonstration of C. trachomatis recovered from infected eyes. Treating chlamydial eye infection in adults means controlling the concomitant genital infection as well. The recommended treatment is oral tetracycline or erythromycin.

Adolescent↗
PubMed1982

Neonatal eye infections caused by Chlamydia trachomatis.

Neonatal conjunctivitis associated with Chlamydia trachomatis has been known since the beginning of the century. Isolation of chlamydiae in eggs, in conjunctivitis of newborns, and from the cervix of their mothers was achieved in the late 1950s. In volunteers, inoculations of ocular and genital strains caused conjunctivitis. Recent studies have shown that incidence figures of chlamydial conjunctivitis in infants are 0.5% to 4%, depending on the prevalence of genital infections by C. trachomatis in the pregnant women in the population studied. Younger women are more at risk. Recurrent, chronic infection and late sequelae may occur unless neonatal chlamydial infection, which is often multifocal, is effectively treated. Serious sequelae of chlamydial infection include pneumonia, which may develop in infants, and post-partum salpingitis, which may occur in infected mothers.

Age Factors↗
PubMed1981

Maternal and infantile infection with Chlamydia in a Swedish population.

Chlamydia trachomatis was isolated from 2.4% of 1 328 puerperal women. The frequency was highest in the age group below 20 years and thereafter decreased with increasing age. Chlamydial conjunctivitis was confirmed in 0.4% of the infants. Two additional cases of conjunctivitis occurred among the exposed infants but chlamydia cultures were not obtained. In a separate ophthalmological material of neonatal conjunctivitis a third of the cases developing within the first month of life was associated with chlamydia. The early and sharp incidence peak for chlamydial conjunctivitis suggested that transmission occurred at delivery. No cases of chlamydial pneumonia were noted. Peroral chemotherapy is recommended in infants for systemic eradication of C. trachomatis.

Adult↗