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Biomedical subjects

R Radford

Publications and source records attributed to R Radford.

15 recordsLinked to original sources
PubMed2000

Decompensation of a congenital retinal macrovessel with arteriovenous communications induced by repetitive rollercoaster rides.

PURPOSE: To describe a congenital retinal venous macrovessel that communicates with a cilioretinal artery and a retinal artery, and to report how this vascular anomaly decompensated as a result of repetitive rollercoaster rides. METHODS: Case report with serial fundus photography and fluorescein angiography. RESULTS: After a short period of intensive rollercoaster rides, a 19-year-old woman complained of reduced vision in one eye. Funduscopy and fluorescein angiography revealed a venous congenital retinal macrovessel with arteriovenous communications, and retinal exudation was visible at the termination of the anomalous vessel. Exudation resolved, and acuity recovered after a period of avoidance of rollercoaster rides. CONCLUSION: This case represents the first report of a retinal artery and a cilioretinal artery communicating with a congenital retinal macrovessel, and it suggests that such patients are at increased risk of retinal vascular decompensation if involved in activities associated with changes in g-forces, such as bungee jumping or rollercoaster rides.

Adult↗
PubMed2000

Severe sclerokeratitis due to Pseudomonas aeruginosa in noncontact-lens wearers.

PURPOSE: To review the clinical presentation, treatment and outcome in four cases of severe anterior segment infection by Pseudomonas aeruginosa unrelated to contact lens wear. METHODS: Four cases presenting over an 18 month period were reviewed. RESULTS: The cases had variable presenting features and outcomes. Complications such as persistent infection, corneal thinning and phthisis bulbi were noted. Possible factors influencing adherence and tissue disruption are discussed. CONCLUSIONS: Suspicion of infection by P. aeruginosa and prompt isolation of the organism is needed early in the course of disease. Intensive and prolonged treatment with parenteral and topical antibiotics combined with judicious use of topical steroid gives the best chance of a favourable outcome.

Aged↗
PubMed1994

Routine pre-oxygenation using a Hudson mask. A comparison with a conventional pre-oxygenation technique.

Two techniques of pre-oxygenation were studied by continuous analysis of respired gases using a mass spectrometer in 10 healthy volunteers. The first was a conventional technique as commonly used in anaesthesia with a Bain system and tightly-fitting anaesthetic face-mask and an oxygen flow of 8 l.min-1. The second technique also used a Bain system with an oxygen flow of 8 l.min-1, but with a Hudson mask attached. The mean fractional end-tidal oxygen concentrations after 3 min were 0.812 and 0.46 respectively for each of the pre-oxygenation techniques against 0.16 for subjects breathing air. This represents a considerable increase in pulmonary oxygen reserve for both techniques. The second technique is not an alternative to conventional pre-oxygenation for emergency anaesthesia, but is a useful and simple method that is acceptable to both patient and anaesthetist in routine cases.

Adult↗