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R Raicević

Publications and source records attributed to R Raicević.

54 records · Page 3Linked to original sources
PubMedDate not supplied

Clinical predictors of cardiac complications in patients with acute ischemic brain disease.

Heart and brain vascular diseases present leading causes of death in civilized world. During development of brain ischemia cardiac complications are possible. The aim of this study was to determine the existence of cardiac complications' clinical predictors by assessing certain electrocardiographic changes in patients with acute ischemic brain disease (AIBD). Forty patients with AIBD, without previous coronary disease history were included in the study. All patients underwent 24 hour Holter monitoring during first 48 hours after the onset of AIBD which was diagnosed by computerized brain tomography. ECG-s were analyzed by computer and interpreted by the same cardiologist. Independent variables in statistical analyses were: age, AIBD, cardiological therapy atherosclerosis risk factors, heart disease history, degree of severity and lateralization of neurological incident and maximal arterial blood pressure values. Dependent variables were: presence/absence of ST depression and presence/absence of ventricular arrhythmias (VA). All parameters as well as their interreaction, were statistically analyzed. Results point that age and side of neurological incident present independent important predictive factors for appearance of ST depression, as well as simultaneous heart ischemia, while the same parameters have border value as predictive factors for VA.

Acute Disease↗
PubMedDate not supplied

[Alpha coma--a prognostic sign?].

We present a patient who has developed cardiac arrest after penetrating cardiac wound and consequent coma, with EEG characteristics of alpha coma. At the same time, auditory evoked potentials-brainstem (AEPB), subcortical and cortical were not within physiological range. During the sixth day of coma, alfa rhythm was substituted with theta and delta frequency, followed by the decreased amplitude and prolonged latency of AEPB and complete absence of cortical and subcortical responses. Lethal outcome occurred in the fifth week of coma with neurophysiological characteristics of complete brain dysfunction. Alpha coma, with EEG presentation that only resemble the normal neurophysiological cortical activity, is rather rare neurophysiological finding present mostly in cardiac arrest, metabolic disturbances and intoxication. It is probably caused by pathological pacers of alfa rhythm, so clinical presentation of alfa coma, specially in a case of cardiac arrest, does not predict a favourable outcome.

Alpha Rhythm↗
PubMedDate not supplied

[Progressive multifocal leukoencephalopathy].

Progressive multifocal leukoencephalopathy (PML) is rare and very severe disease, classified into the group of subacute and viral infections of central nervous system (CNS), and can simulate clinical pictures of numerous degenerative diseases of nervous system. PML was firstly described in 1958, and pathologic-morphologic substrate was explained in papers of Astron et al. Many years later, definitive diagnosis of PML was histopathologic, on the autopsy material. The fact that it is very rare and severe disease, very rarely diagnosed in clinical conditions, is the reason of our decision to present this case.

Adult↗
PubMedDate not supplied

[The Fahr syndrome].

Fahr's syndrome is a rare clinical entity consisting of certain metabolic, biochemical, neuroradiologic and neuropsychologic phenomena in which extrapyramidal phenomenology clinically dominates. In this report, primarily from educational reasons, we have presented a female patient, who was before admittance to our clinic examined in one Belgrade hospital for headache, stiffness of trunk and extremities and the diagnosis was migraine with depressive reactions. However, as the discomforts were persistent, she was admitted to our clinic and after the investigation, especially for the presence of extrapyramidal clinical phenomenology with dominantly pronounced increase of tonus with the presence of amorphous calcifications in basal ganglia on both sides it was concluded that she was suffering from Fahr's syndrome.

Adult↗
PubMedDate not supplied

Increased titer of anticardiolipin antibodies represents the risk for the development of ischemic brain disease in persons below 50.

The aim of this paper was to investigate the frequency of increased ACLA titer in patients with ischemic brain disease (IBD) and to define their clinical profile. The group consisted of 162 IBD patients of both sexes, aged 39-81 years, with 50 healthy volunteers and 23 patients with other neurological diseases as control. Increased ACLA titer (above 0.9 GPL U/l IgG and 0.5 MPL U/l IgM) was registered in 17.9% IBD patients, and more frequently in patients with transitory ischemic attacks (TIA)-32.6%; slightly increased titer predominated (0.9-20 GPL U/l IgG and 0.5-15 MPL U/l IgM) in 69% IBD patients, while moderately increased (20-80 GPL U/l and 15-50 MPL U/l IgM) was present in 21% IBD patients, while highly increased titer (above 80 GPL U/l IgG and above 50 MPL U/l IgM) was present in 10.3%; IgG class was most frequently increased (9.2%), than IgM-5%, while increase of both classes was present in 3.7%. All patients with increased ACLA titer were below 50 years of age, had history of previous IBD attacks, more often TIA, irregularity of at least one coagulation test and fewer risk factors for IBD. Hence, increased ACLA titer was present in IBD patients of both sexes, below 50 years of age with previous history of IBD attacks and fewer atherosclerosis risk factors.

Adult↗
PubMedDate not supplied

[Comparative study of the analgesic effect of Dikalm and Saridon in headaches of various causes].

Headache, as a syndrome, represents large health and wider socio-economic problem in every community for its massive occurrence and frequent absence of therapeutic response to the administered analgesics. That is why the finding, and later production of the drug that would satisfy the criteria of analgesic, efficacious in the treatment of headache, without the entering in etiology of syndrome are presented as the imperative. In connection with that was set the aim of the investigation: to investigate comparative analgesic efficacity of new preparation--Dikalm compared to analgesic that was for a long time present in our pharmaceutic market--Saridon tablets in the patients with different neurologic diseases, where headache represents the leading symptom of their difficulties. The investigation included 30 patients--10 patients were cross-examined with the use of both preparations in the treatment of headache episodes that appeared in separate time interval, and 20 patients received one another preparation. The headache intensity, residual headache, adverse effects and the need for repeating were graded by original standardized scales. The results of investigation revealed significantly better analgesic effect of therapeutic combination contained in Dikalm preparation, as for persistent, residual headache, as for the need of repeating the analgesics administration, what was specially pronounced in the group that cross-received both preparations, or in the whole group compared to the therapeutic combination contained in Saridon tablets. It was concluded that Dikalm represented the drug with efficacious analgesic and with minimal adverse effects.

Acetaminophen↗
PubMedDate not supplied

[Convulsion-conversion epilepsy--a problem in differential diagnosis].

Epilepsy is chronic, multietiologic disease of the cerebrum, with different clinical features and with frequent occurrence of emotional and psychic disorders. In this report, we presented the case of female patient, 16 years old, examined in our Clinic twice. The diagnosis of epilepsy was established on the basis of the following examinations (EEG, Holter EEG, MR of the head) and Carbamazepine was included in the therapy. Afterwards, in the patient, instead of grand mal seizures, occurred atypical nonconvulsive prolonged seizures, without postictal phenomena, and after the repeated observation, psychological confrontation and according to the bizarreness of certain seizures the case of conversional-convulsive epilepsy was confirmed, and for that reason we decided to publish this report.

Adolescent↗
PubMedDate not supplied

[Carotid-cavernous fistula with spontaneous remission].

Carotid-cavernous fistulas (CCF) represent the complication of traumatic injuries mostly of bone structures of skull base and face, and rarely of soft neck tissues with the fast development of the shunt and imperiled hemodynamics that in a short time endangers the patient for the increase of intracranial mass. The therapy of this clinical entity significantly changed in the last few years. In this report, we present the case of spontaneous CCF healing with the complete restitution of neurological deficit and CCF healing in control angiographies.

Adult↗
PubMedDate not supplied

[Analysis of antihypertensive therapy in patients before acute cerebral ischemic disease].

The adequacy of therapeutic program for hypertensive disease in the patients with ischemic brain disease was analyzed in the study related to the administration of the drugs divided by the groups of antihypertensive drugs. The results had demonstrated that in over 50% patients the therapy had to be changed by introducing at least one hypertensive drug from the other group. In many cases were observed inadequate doses of antihypertensive drugs and the prescription of antihypertensive drug in minimal dose, although therapeutic response was not adequate. In significant number of cases (over 80%), the patients were irregularly taking the prescribed therapy, and only 18% had the regular controls. The results of this investigation indicated that on one side did not exist the adequate therapeutic program for hypertension control and on the other the significant number of patients irregularly used the proposed therapy and did not control the disease regularly.

Antihypertensive Agents↗
PubMedDate not supplied

[Neurologic disorders in a patient with autoimmune hemolytic anemia].

Completely different entities might be with the same possibility in the baseline of interweaving of symptoms and signs of nervous system damage. One of them, the deficiency of vitamin B12 very frequently causes megaloblastic anemia and funicular myelosis. In the case of our patient, after the clinical picture of hemolytic anemia was revealed, by slow-progressive course was developed neurologic deficiency that, according to its features, could have the deficiency of cobalamin and folic acid in its etiologic background. On the basis of disease course, clinical finding, numerous clinical investigations so as the reaction to applied therapy it was assumed that the patient had besides confirmed autoimmune hemolytic anemia the pernicious anemia as the associated cause of anemic syndrome and the basic reason of the development of neurologic deficiency. Described is the frequent associated occurrence of pernicious anemia and antiglobulin positive hemolytic anemia, so as the significant association of pernicious anemia with the deficiency of immunoglobulins that was otherwise observed in our patient as the permanent IgA deficiency.

Adult↗