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Biomedical subjects

R Rajaniemi

Publications and source records attributed to R Rajaniemi.

6 recordsLinked to original sources
PubMed1985

Subjective symptoms among dental technicians exposed to the monomer methyl methacrylate.

Dental technicians, their technical aids, and the students of the State Institute for Dental Technicians during a single academic year were surveyed for their use of the acrylic ester monomer and subjective symptoms in a questionnaire study. The population under study included all the members of the trade union in the greater Helsinki area and all specially trained technical aids in Finland. Acrylic monomers were handled daily without skin protection by 81% of the 293 respondents. Current hand dermatitis, or previous local dermatological problems, was reported by 17% of the respondents. Frequent contact with the acrylic monomer increased the rate of the self-reported dermatitis. The symptoms were spontaneously reported to be associated with the monomer by 42% of the respondents. Previously experienced allergies seemed to predispose the subjects to these irritative reactions. Other finger symptoms, eg, whitening and feelings of numbness, coldness, and pain, were reported by 25% of the respondents. Students attending the four-year technical school reported an increasing frequency of finger symptoms as their studies advanced, and in their senior year they reported the same frequency of occurrence as the qualified dental technicians.

Adolescent↗
PubMed1984

Local neurotoxicity of methyl methacrylate among dental technicians.

Dental technicians often handle methyl methacrylate bare-handed before the polymerization reaction, and the monomer can penetrate the skin during the process. Nerve conduction velocities were determined in 20 dental technicians who had slight neurological complaints and in 18 healthy control persons. The motor and sensory conduction velocities in the forearm sections were normal and similar in both the study and the control group. Dental technicians had significantly slower distal sensory conduction velocities from the digits I, II and III on the right hand and also from the radial aspects of the digits II and III on the left hand than did the controls. Findings are considered to represent mild axonal degeneration on the areas with the closest and most frequent contact with methyl methacrylate.

Adult↗
PubMed1984

Hand dermatitis in dental technicians.

The incidence of hand dermatitis and contact allergies was analyzed among dental technicians. A survey was carried out by postal questionnaire. It was returned by 106 technicians (88%); 30 had had skin problems, and 20 (19%) had present eruptions. All 20 were invited to a detailed dermatological investigation, but only seven participated. Epicutaneous tests to prosthetic materials were negative in these patients. The hand eruptions in 4 patients appeared to be irritant. 4 other patients (4%), who had had previous hand dermatitis, had a history of positive patch test reactions to methyl methacrylate, but they had become symptomless and refused to participate in further studies.

Adult↗
PubMed1983

Local neurotoxicity of methylmethacrylate monomer.

A technique was devised which allowed a controlled exposure to methylmethacrylate liquid on rat tail skin. The procedure was repeated 3 h daily for 8 weeks. This caused keratolysis without ulcerations in the exposed skin and abnormal muscle responses to stimulation of the rat tail motor nerves by a skin electrode through the treated area after 4 weeks of exposure. The motor conduction time did not differ from controls. The results point to a local neurotoxic reaction by the absorbed methylmethacrylate. This technique may prove valuable in experiments on the determination of dermal and local toxicity of new chemicals.

Animals↗