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Biomedical subjects

R Reichardt

Publications and source records attributed to R Reichardt.

16 recordsLinked to original sources

Kinetics of antipyrine and sulfamethazine in patients recovered from dihydralazine-hepatitis.

Pharmacokinetic studies with sulfamethazine (500 mg) and antipyrine (15 mg/kg) were performed in 27 hypertonic patients (16 females, 11 males, 37-78 years) who had recovered from a dihydralazine-induced hepatitis, and 21 patients with essential hypertension (13 females, 8 males, 18-74 years) treated with antihypertonics excluding dihydralazine. 20 patients of the hepatitis group (74%) and 12 patients of the control group (57%) were slow acetylators. With regard to the pharmacokinetic parameters no differences were found in both slow and rapid acetylators between the sulfamethazine group and the antipyrine group.

Acetylation↗

[Zinc oxide phosphate cement studies on the usefulness of Firmat].

The aim of the present investigations was to evaluate the Firmat zinc oxyphosphate cement in comparison with other brands, especially Adhesor normalhartend. The results obtained show that Firmat is a fast-setting phosphate cement which is not suited for polyhedral cavity linings. Time and material-consuming reworking is necessary. For temporary fillings, a temporary filling material should be used which is sufficiently solid, but easier to remove.

Drug Evaluation↗