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Biomedical subjects

R Ringelmann

Publications and source records attributed to R Ringelmann.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Bacteriological examination of bronchitis and pneumonia. Part I: Is sputum an appropriate material to be examined?--a literary review (author's transl)].

In a literary review the respiratory tract in its physiological condition, the causative agents of bacterial pneumonias and bronchitides are taken into consideration as are also concerned with the question of the suitability of sputum as a material to be examined by infections of the lower respiratory tract which above all with regard to the diagnostic value to other materials as transtracheal aspiration (TTA), bronchial aspiration (BA) and lung aspiration (LA) specimens.

Bacteroides↗
PubMed1981

[Bacteriological examination of bronchitis and pneumonia. Part II: quantitative analysis of homogenized sputum with respect to leucocytes, protein, erythrocytes and bacteria (author's transl)].

This study is concerned with the value of bacteriological sputum examination by lower respiratory tract infections. Prominence was given to quantitative aspects; colony forming units and markers of infection as leucocytes, albumin and erythrocytes were determined from homogenized specimens. It turned out that numbers exceeding 10(6) per ml of pathogenic bacteria correlated in more than 90% with clinical evidence of bronchitis or pneumonia if cases with antibiotic treatment are not taken into account. There is, in addition to that, more than 90% correlation between the number of colony forming units of these sizes and a leucocyte count of more than 20 per 125 magnification field, which is significant of infection. The markers of infection mentioned above, can be determined by a simple semi-quantitative test-stick method. It was possible to show good relation between the number of leucocytes counted by microscope and the "Cyturtest". Compared to the "routine method" especially pneumococcus and H. influenzae could be isolated much more frequently by applying the method of homogenizing sputum. The rough quantitative informations of the "routine method" did hardly coincide with the exactly determined bacterial numbers.

Blood Proteins↗
PubMed1979

[Studies on normal range of serum IgE concentration (author's transl)].

To obtain information about the normal range of IgE concentration in serum a random population of male and female patients was divided into 14 age groups. Based on the mean values (x +/- 1s) an age dependency is clearly recognizable with an increase of the IgE concentration at one and two years of age, a constant IgE concentration during the middle age period, and a decrease of the IgE level in the 40th year of age which becomes especially obvious after the 60th and 80th year of age. From the distribution pattern of IgE levels within the different age groups it is evident that only the curves of newborns and persons over 80 years resemble a normal Gaussian distribution. The other age groups show 2 or 3 peaks of IgE. However, these peaks represent only 50% of the total IgE concentration. A similar distribution pattern was obtained by IgE determinations in 100 "healthy" blood donors which showed no clinical evidence of allergy. The age dependent normal ranges given in this paper make it possible to evaluate increased IgE levels accordingly.

Adolescent↗
PubMed1978

[Malaria: 4 case reports with "atypical" symptoms (author's transl)].

Four cases of malaria are described. Five to nine days elapsed between the onset of clinical symptoms and the beginning of the anti-malaria chemotherapy. One of the patients died under signs of massive and nearly synchronous hemolysis during the last two hours of treatment. The Malaria tropica disease of the first and the second patient were first diagnosed as common cold with enteritic symptoms; the third patient showed signs of abdominal thyphoid fever and developed symptoms of intravascular coagulation. With the fourth case-Malaria tertiana-it shall be remembered that, if chemoprophylaxis starts too late, the disease is not suppressed but can be delayed: incubation period lasted ten weeks. The diagnostic procedure for the clinician and the pathogenetic mechanism are discussed: massive hemolysis and the possible influence of the chloroquine therapy, the intravascular coagulation and the elevation of the IgE level.

Adult↗
PubMed1977

[Reservoir for bacteria of urinary tract infections in urologic patients (author's transl)].

Many infections of the urinary tract, especially after surgical treatment are nosocomial infections. The etiological bacteria could only be found in the urine of the infected patients and in the faecal flora of nearly 40% of all stationary patients. The so called "problem bacteria": Klebsiella, Proteus rettgeri, pseudomonas showed increasing drug resistance during the observed period between 1972-1975. The bacteria isolated from the faecal flora also showed multiple drug resistance. Thus we concluded that the antibiotic regime in these patients is very important for the selection and the increase of the problem bacteria both in urine and in the faecal flora.

Anti-Bacterial Agents↗
PubMed1977

[Viral haemorrhagic fever].

Two outbreaks of haemorrhagic fever caused by a Marburg-like virus occurred in the Sudan and Zaire from August to November 1976. The inital epidemiological investigations and emergency control measures were carried out by Sudanese and Zairian health personnel and several of them unfortunately died in the course of their duties. In view of the unusual gravity of the outbreaks and the unknown nature of the agent, assistance was provided by a WHO team in the Sudan and a multinational team in Zaire. A consultation arranged by WHO was held at the London School of Hygiene and Tropical Medicine in January 1977 to review the experience acquired during these outbreaks and to make recommendations which, to a large extent, may be applicable to other outbreaks of suspected viral haemorrhagic fever. Because it is felt that this information would be of value to many health administrations, large abstracts of the report of this consultation are given here.

Democratic Republic of the Congo↗
PubMed1976

[Fatal diphtheria in a 26-year-old man. Repetitorium; Known and current aspects of diphtheria].

This paper reports on a 26 year old male who died of toxic diphtheria with all typical features such as: Bullneck, paralysis of the soft palate, renal failure accompanied by proteinuria and--most notably--myocarditis (very typical microscopically) with circulatory disturbances and finally left and right hand failure. The myocarditis hat caused increases of SGOT, SGPT, CPK, LDH and HBDH to values not seen before by us in the course of myocarditis. The patient had been immunized against diphtheria as a child. Initial treatment consisted of the application of ampicillin which caused rapid regression of the local symptoms in the pharyngeal region including the bullneck-symptom; of course the course of intoxication was not influenced, even after the patient had been admitted to the hospital, the disease correctly diagnosed and antitoxin given three days before death.

Adult↗
PubMed1976

[Evaluation of successful chemotherapie of infections of the urinary system by determination of antibacterial activity in the urine (author's transl)].

5,589 urin samples from patients with suspected infections of the urinary tract were screened for inhibiting activity against Baz. cereus (ATCC 6051). In 19% of these urines such inhibitors could be found. In spite of the antibacterial inhibition activity nearly half of the samples had bacteria in high number. By comparison of the various bacterial species in both groups of urin, in those without antibacterial "Problem-Bacteria": Klebsiella-Enterobacter- Proteus- Candida-species is demonstrated. If one compares the urine of the same patient before and under chemotherapie it seems as if antibiotic therapie is often started without proof of significant bacteriuria. In those patients, where there was a significant bacteriuria in the first urine sample only 7 from 20 showed sterile urine under chemotherapie; 10 patients had an other species in the second sample and 3 patients had the same species isolated from urine during therapie. The diagnosis and the consequences especially for therapie in stationary patients with recurrent infections is discussed.

Anti-Bacterial Agents↗