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Biomedical subjects

R Rizzi

Publications and source records attributed to R Rizzi.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

A histological study of hepatitis delta virus liver disease.

The histopathology of hepatitis delta virus disease was studied in carriers of HBsAg with chronic hepatitis delta antigen-positive hepatitis and in serial biopsies of patients with acute hepatitis delta virus hepatitis that progressed to chronicity. There was no histologic feature distinctive of hepatitis delta virus from other types of viral hepatitis. Biopsy specimens of patients with chronic disease exhibited portal and periportal inflammation with piecemeal necrosis, conforming to a picture of aggressive hepatitis often accompanied by cirrhosis. Characteristic was a marked intralobular infiltration by mononuclear cells and a degenerative eosinophilic change of the hepatocytic cytoplasms conducive to the formation of acidophilic bodies. Liver specimens from patients with hepatitis delta virus hepatitis exhibited aspects of focal, confluent and bridging necrosis. The disease progressed to chronicity irrespective of the original histological features. The expression of intrahepatic hepatitis delta antigen was reduced in the phase of the acute hepatitis but increased in parallel with the development of chronic active liver disease. In late-stage cirrhosis, expression of hepatitis delta antigen was usually low.

Acute Disease↗
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[Hyperthyroidism and cholestasis: a case report].

Intrahepatic cholestasis has rarely been observed in patients with thyrotoxicosis and generally occurs in association with coexistent congestive heart failure. We report the case of a 63-year-old man who was referred to our Institution because of jaundice and hyperthyroidism. During his hospital stay, his plasma bilirubin level reached 27.41 mg/dL. Clinical, biohumoral, and instrumental examinations excluded heart failure and autoimmune or viral hepatitis. After the start of therapy with methimazole, thyroid hormone and plasma bilirubin levels decreased progressively and simultaneously, eventually returning to normal. Plasma bilirubin values as high as the ones we recorded, in the absence of congestive heart failure or autoimmune chronic hepatitis, have not, to our knowledge, been previously reported.

Bilirubin↗
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[Treatment of supra-aortic trunk aneurysms: report on 16 cases].

The Authors report their own experience in treating 16 patients suffering from aneurysms of the supra-aortic trunks, 6 of the innominate artery, 4 of the common carotid artery, 3 of the intrathoracic subclavian artery and 3 of the extrathoracic subclavian artery. Eleven cases were of atherosclerotic nature, 3 from Takayasu's, 1 dysplasic and 1 mycotic. To aneurysms of the innominate artery with diameter less than 2 cm and one of the subclavian artery, in a patient with on carcinoma of the lung, was treated non surgically; all other patients were operated. The mortality was 0, and morbidity rate very low. With a mean follow-up of three years, only a patient, with Takayasu's disease, developed a recurrence and one, with mycotic aneurysm, died from persistence of the sepsis.

Adolescent↗
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[Nerve block in the treatment of cranio-facial pain].

The purpose of antalgic nervous block is described and the reasons why a patient suffering from pain syndrome should be examined at the same time by a multidisclipinary team (whos composition will vary depending on the site of the pain) are explained. Such a team will also include the anaesthetist, maxillofacial surgeon, neurologist, neurosurgeon, orthopaedist, radiophysiothherapist, non-medical psychalagist and neurologist. 2436 antalgic nervous blocks undertaken between 17-3-1963 and 31-5-1974 on the head and neck are reviewed. They are analysed in relation to the site of the block, the pathology, the anaesthetic used, and complications. Long-term results are mentioned in brief.

Autonomic Nerve Block↗
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[First aid to patients with multiple facial injuries].

The first aid techniques available for treating patients with multiple face traumas are reviewed: first aid proper (mouth-to-mouth respiration, mouth-to-nose respiration and external heart massage); picking up the patient (radio-TV link between ambulance and Resuscitation Department); transport (rationally planned ambulance with expert in resuscitation aboard); reception area (with radio-TV link, the Resuscitation physicianc can alert staff in the ward to which the patient should be admitted).

Emergencies↗
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[The emergency treatment of aneurysms of the supra-aortic trunks and of the internal carotid].

In the last 10 years, four patients with aneurysms of the supraaortic trunks and the internal carotid artery have been operated in emergency at Department of Vascular Surgery of University of Bari. The first case was a mycotic aneurysm of the carotid bifurcation, the second an aneurysm of internal carotid artery interesting the retropharynx, the third a post-operatory pseudoaneurysm of common carotid in a patient affected by Takayasu's disease and the last an atherosclerotic aneurysm of the innominate artery. Clinical picture suggested an immediate surgical treatment in all patients. Different procedure were used depending on size and localization of each lesion. Results in all cases have been satisfactory. The aneurysms of supraaortic trunks and of internal carotid artery are very rare; therefore when clinical picture is dramatic or quickly worsening, emergency treatment is mandatory in order to reduce mortality risk and minimize complications.

Adult↗
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Helicobacter pylori infection: comparison among four different therapeutic regimens.

Helicobacter pylori is both virulent and pathogenic, yet it is not clear what is the best way to treat the infection. This study compares the ability of 4 regimens of colloidal bismuth subcitrate (CBS) 120 mg q.i.d. for 4 weeks, combined with one or two antibiotics, to eradicate helicobacter pylori and assesses the outcome of eradication on antral gastritis and on symptoms of non-ulcer dyspepsia in 140 consecutive subjects (44 duodenal ulcers and 96 non ulcer dyspepsia). Endoscopy with antral biopsies was repeated in all patients before (T0) and one month after stopping treatments (T2) while duodenal ulcers were endoscoped also at the completion of treatments (T1). The four regimens showed similar eradication and ulcer healing rates (p = ns). After treatments (T1), about 60% of dyspeptic patients achieved a subjective improvement, not significant despite therapeutic regimen, and persisting at T2. Antral gastritis significantly improved after treatments (p less than 0.0001), even with the persistence of the infection (p less than 0.001). The 4 regimens are relatively safe, as no abnormality in laboratory assessment was found, albeit the frequency of side effects (most of whom tinidazole related) and the difficulty of the schedules (6-10 tablets/day) may limit patient compliance.

Adolescent↗
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[Custom mouthguards: indications and construction].

Dealing with the personal endoral protections today it is possible to choose between different methods, which present various difficulties in application, but result in being more functional and comfortable than semi-individual protections. The cost shouldn't be a determining factor in athletes wanting maximum performances. In addition, in the case of athletes with cranium-mandibular diseases, articular clicks, and other problems, the personal endoral protection, represents not only an efficient method of prevention, but serves as a therapy.

Athletic Injuries↗