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R Rodríguez Díaz

Publications and source records attributed to R Rodríguez Díaz.

6 recordsLinked to original sources
PubMed2002

[Prone versus what?].

Background It has been known for many years that the risk of sudden infant death syndrome (SIDS) is reduced by the supine sleeping position. Campaigns are required to increase awareness of this finding among all those involved in childcare (parents, relatives, kindergarten staff, health professionals etc.).ObjectiveTo determine knowledge of the best sleeping position among health professionals (physicians and nurses) and the parents of healthy neonates.Material and methodThe study was performed in a tertiary maternity hospital. A voluntary, anonymous questionnaire containing an item on the best sleeping position for neonates was distributed. The influence of parental age, occupation, education, and previous children was analyzed.ResultsThe side position was the most frequent answer among parents both in the first questionnaire (50.9 %) and in the second (46.8 %). Health professionals preferred the supine position (63.3 %). Parents who gave the right answer had a higher mean age, were more likely to work outside the home and to be better educated. The existence of previous children did not influence the answer.ConclusionsIn some maternity hospitals, parents still believe the side sleeping position to be best for their children. To provide an example in maternity wards, all health professionals should accept the supine position as the best for preventing SIDS.

Humans↗
PubMed1991

[Changes in tissue oxygen extraction in patients with acute respiratory insufficiency].

We analyzed the tissue oxygen extraction in 25 patients with acute respiratory failure. Fourteen met the clinical criteria for the adult respiratory distress syndrome (ARDS). The 11 remaining patients had acute respiratory failure with causes different from ARDS. In all cases the changes in the oxygen extraction ratio (O2ER) and in the oxygen consumption (VO2) were evaluated after changing oxygen availability (O2A) with positive end-expiratory pressure (PEEP) and dobutamine infusion. The patients with ARDS showed a change in VO2 parallel to O2A changes, with a significant correlation (r = 0.85); however, no changes were found in O2ER (r = 18). In the patients without ARDS, the changes in O2A did not modify the VO2 (r = 0.02) but there was a significant inverse relationship between DO2 and O2ER (r = -0.70). These findings suggest an abnormal regulation of tissue oxygen extraction and an abnormal dependence of VO2 on O2A in cases with ARDS. Dobutamine therapy, in addition to inotropic effects, could improve a situation of hidden hypoxia, as it is a vasodilator that might act on microvasculature.

Acute Disease↗
PubMedDate not supplied

[Assessment of the cellular immune response induced in Balb/C mice with dengue virus 2 envelope protein].

The cellular immune response to dengue type 2 virus envelope protein was studied. To this end, the lympho-proliferative capacity of T-lymphocytes obtained from splenocytes of animals immunized with the protein when they were stimulated by such protein and dengue 2 virus. It was realized that splenocytes proliferated significantly in response to both types of viral antigens and that the values of stimulation indexes were higher in response to the whole virus than to the protein alone. Based on the above-mentioned, it was concludes that purified dengue 2 virus envelope protein was capable of generating specific and memory responses of antigen T-cell to dengue 2 type virus.

Animals↗
PubMedDate not supplied

[Monoclonal antibodies to dengue virus 4: the spectrum of the reactivity to 4 serotypes of dengue].

These types of monoclonal antibodies 8E8, 3F7 and 1E9 to dengue 4 virus H-241 strain. These monoclonal antibodies show various patterns of reactivity to the four dengue serotypes and different antigen preparations of serotype 4 when they were tested in various serological methods. The monoclonal antibody 8E8 exhibited a specificity of serotype (D-2; by hemagglutination inhibition); subcomplex (D-2 and D-4 by immunofluorescence) and complex (by immunoperoxidase technique). It was able to neutralize by 80% homologous virus and it turned out to be the only reactive monoclonal antibody in the complement fixation test. The monoclonal 3F7 did not react to by hemagglutination inhibition, recognized serotypes D-1, D-2, D-3 and D-4 by immunofluorescence and only serotypes D1 and D4 by immunoperoxidase technique but it was unable to neutralize the homologous virus. The 1E9 antibody was reactive to serotypes D1, D-2, D-3 and D-4 only by hemagglutination inhibition and neutralized serotype D-4. All the monoclonal antibodies were able to react to various dengue antigens through an ELISA of double antibody and showed fluorescent activity against 38th pass in Beagle dog kidney culture; however, they could not react to a D-4 recombinant antigen.

Aedes↗