Biomedical subjects

R Rogozea

Publications and source records attributed to R Rogozea.

At least 55 records · Page 3Linked to original sources

PubMedDate not supplied

Retention of orienting reaction habituation in chronic alcoholics.

A polygraphic study on resistance to habituation of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration) and EEG (acoustic evoked potential and EEG-blocking reaction) components of the orienting reaction elicited by a repetitive auditory stimulus during successive (weekly) session was performed in 67 chronic alcoholics and in 70 matched normal subjects (control group). The study showed significant retention disturbances of orienting reaction habituation (i.e. of learning), the "saving" of stimulations achieved from one session to the other to obtain the habituation criterion, being lesser in alcoholics than in control normal subjects. The severity of habituation retention disturbances depended on the patients' age, type of alcoholism, alcohol consumption intensity and chronicity, as well as the type of resting EEG.

Acoustic Stimulation↗

PubMedDate not supplied

Orienting reaction in therapy-resistant generalized epilepsy.

A polygraphic study of the somatic, autonomic and EEG components of the orienting reaction elicited by an auditory stimulus was performed in 39 epileptics with therapy-resistant generalized seizures (TRGS) and in 119 matched subjects in two control groups. The study showed a significant interictal hyperresponsivity in epileptics with TRGS vs. the normal subjects of control group I, which consisted in a marked increase of the intensity of the orienting reaction components. This hyperresponsivity was also more marked than that noted in epileptics with therapy-controlled generalized seizures of control group II. The correlation analysis of data showed that the severity of these responsiveness disturbances in epileptics with TRGS depended on the patients' age, type of electroclinical seizures, pretrial seizure frequency, type of resting EEG, administered treatment (no. of administered antiepileptic drugs/patient), daily dose, as well as on the serum level of these drugs. The multivariate regression analysis showed that the most significant predictive variables for the responsiveness disturbances were the pretrial seizure frequency, type of electroclinical seizures, daily dose of administered antiepileptic drugs and their serum level. The data also evidenced that the antiepileptic treatment improves the interictal responsiveness disturbances, the effect being the more marked as the treatment was more sustained. The above-mentioned responsiveness changes in epileptics with TRGS should be ascribed to some disturbances in nervous excitability.

Adolescent↗

PubMedDate not supplied

[The neurochemical bases of absence-type epilepsy].

The author attempts to introduce several of the present data concerning the neurochemical basis of one of the most enigmatic neurological disturbances, the so-called "petit mal" epilepsy. The present material is based on some of the most recent studies of neurochemistry, and considerations are also made concerning the experimental modelling of "petit mal" epilepsy.

Animals↗

PubMedDate not supplied

Extinction of orienting reaction in chronic alcoholics.

A polygraphic study on resistance to extinction of the somatic (EMG), autonomic (finger plethysmogram, galvanic skin reaction, respiration) and EEG (acoustic-evoked potential and EEG-blocking reaction) components of the orienting reaction elicited by a repetitive auditory stimulus was performed in 67 chronic alcoholics and in 70 matched normal subjects (control group). The study showed a significantly lower resistance to extinction of the orienting reaction in alcoholics than in control normal subjects. The severity of this extinction disturbance depended on the patients' age, type of alcoholism, alcohol consumption intensity and chronicity, as well as the type of resting EEG.

Acoustic Stimulation↗

PubMedDate not supplied