Biomedical subjects
Publications and source records attributed to R Ronzoni.
Medial meatal fibrosis is a rare entity which is linked to inflammatory and traumatic factors. This pathology significantly benefits from surgical management. Criteria for achieving successful results are strict and concern the complete removal of the fibrous tissue and covering of the bony canal with skin graft. The aim of this paper is to present our experience with this rare pathology and to discuss current approaches.
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We report the case history of a 24-year-old woman with an acoustic neuroma diagnosed during the 24th week of pregnancy. Diagnostic steps and surgical management of this uncommon condition, which represents a therapeutic challenge, are discussed.
The object of the present paper is to review 39 cases of acute mastoiditis treated surgically at the 2nd and 4th ENT Clinics of the University of Rome 'La Sapienza'. The aetiological factors were investigated observing an association of the acute mastoid abscess with cholesteatoma. Moreover 5 patients developed mastoiditis after previous mastoid surgery. The rationale of surgical management is discussed.
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The purpose of this work was to compare pre- and post-operative facial nerve function between unmonitored and monitored cases of skull base lesions. The study involved 32 patients suffering from lateral skull base tumours (10 unmonitored and 22 monitored). Facial nerve function was monitored intraoperatively by an acoustic facial electromyographic system (NIM-2). Post-operative facial function was graded according to the House-Brackmann scale. In the group of monitored cases, facial nerve function was normal (Grade 1 or 2) in 79 per cent of the patients, while the unmonitored patients showed normal function in only 50 per cent of the cases. These results confirm previous observations that audible evoked electromyographic monitoring significantly reduces permanent facial nerve dysfunction.
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The present study was specifically designed to ascertain the effect that otoneurosurgical or neurosurgical approaches may have on the contralateral ear. 18 patients suffering from different histologic lesions were examined. Pure-tone audiometry was performed before and after surgery each postoperative day up to the fourteenth day. The audiograms were abnormal after surgery in all but one of the patients tested. This hearing loss was transitory and the recovery occurred completely within 3 months. These outcomes suggest that the hearing loss was linked to a loss of cerebrospinal fluid.
Various techniques and materials have been proposed to deal with problems connected with radical cavities including recurrence of inflammatory processes, requirement of regular medication, social inconvenience (i.e., inability to practice any water sport, work in adverse environment, etc.). The present paper details the results of revalidation of old radical cavities using as filling a mixture of tricalcium phosphate and hydroxyapatite granules. Three techniques were used in reconstruction of the posterior canal wall. In the first procedure, the material was incorporated with fibrin adhesive to fill the cavity. In the other two methods the ceramic granules were covered respectively with a sheet of bone pate-fibrin sealant or with septal cartilage homografts. Twenty-four patients with chronic discharging old radical cavities were operated with anatomic results of 91.7 percent successful graft taken. The functional results showed an air-bone gap less than 30 dB in 72.7 percent of the cases after 6 months. After 2 years hearing gain was satisfactory in 63.6 percent of the patients. The different methods of reconstruction of posterior canal wall did not influence these findings.
The aim of the present study was to evaluate the effect of experimental perilymphatic fistula on cochlear electrophysiological responses. Six albino guinea pigs, in which recording electrodes were implanted in order to record the electrocochleogram, were used. Experimental protocol investigated cochlear responses before the induction of the fistula in the round window membrane perforation and then two month later. Compound action potential thresholds increased immediately after perforation of the round window membrane. The thresholds rapidly recovered. This phenomenon was accompanied by clear-Out reduction in amplitude upon suprathreshold stimulation. This latter observation associated with a decrease in the amplitude of the threshold seems to be a specific audiologic sign of the fistula. The clinical implication are discussed.