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Biomedical subjects

R Rottiers

Publications and source records attributed to R Rottiers.

At least 37 records · Page 2Linked to original sources
PubMed1981

Glucose uptake and insulin secretory responses to intravenous glucose loads in the dog.

Twenty-one healthy young non-anesthetized Dalmatian dogs (10 male, 11 female) were given IV glucose loads between 300 and 1,500 mg/kg of body weight in a standard time period of 30 s. The fractional glucose turnover rates and the insulin peak responses gradually increased with glucose loads to 1,000 mg/kg and the total insulin secretion with loads to 1,250 mg/kg and remained constant. The insulinogenic index (delta I/delta G) varied inversely with the size of the glucose loads. The pattern of responses indicates that the optimum glucose load is near 600 mg/kg for evaluating normal glucose metabolism in dogs by the IV glucose loading technique.

Animals↗
PubMed1979

Effects of long-term treatment with suloctidil on blood viscosity, erythrocyte deformability and total fibrinogen plasma levels in diabetic patients.

1-(4-Isopropylthiophenyl)-2-n-octylaminopropanol (suloctidil, Sulocton), a drug introduced into clinical practice for the treatment of cerebral and peripheral vascular insufficiency and its complications, has been shown to decrease blood hyperviscosity after long-term treatment in diabetic patients. Suloctidil was particularly effective in lowering measured blood viscosity at high shear rate (230 s-1). At low shear rate (0.77 s-1) a decreasing effect was also observed but reached a statistically significant level only after one month. Since neither total plasma fibrinogen levels nor red blood cell deformability were modified by suloctidil treatment, its lowering effect on blood hyperviscosity could be due to a hitherto unrecognized mechansim of action.

Adult↗
PubMed1977

Genetic study of hyperlipoproteinaemia types IV and V.

In a family, of which 32 members belonging to three generations could be examined, 21 subjects were normal, while 11 were affected by hyperlipoproteinaemia types IV and V or related biological disorders. Neither an autosomal dominant inheritance nor an autosomal recessive inheritance nor a multiple-type hyperlipoproteinaemia can unreservedly be accepted.

Chylomicrons↗