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R Rueda

Publications and source records attributed to R Rueda.

27 records · Page 2Linked to original sources

Detection in a murine T lymphoma of a lipid-like factor that inhibits cell growth.

In this paper we show that MCG3 cells, a murine T lymphoma, contain a factor(s) that inhibits the proliferation of cells of different histological origin. The lack of sensitivity of this cell proliferation-inhibiting factor (CPIF) to the treatment with proteolytic enzymes and its solubility in organic solvent demonstrated that it is a lipid-like substance. Separation by thin-layer chromatography showed it migrates before the prostaglandins with activity on cell proliferation. CPIF activity was reversible and more intense on bone marrow cells than on tumor cells, suggesting that it can play a role in cell growth regulation.

Animals↗

[Study and characterization of lipid factors that inhibit cellular proliferation in MCG3 rat T lymphoma].

Lipid factors that inhibit cellular proliferation have been detected in MCG3 cells, a T lymphoma of B10 mouse. The inhibiting effect is cytostatic, non cytotoxic, reversible and lacks species and tissue-specificity. These lipids have been isolated by Thin Layer Chromatography (chloroform:methanol:water, 60:38:8) showing an Rf100 between 36 and 42, similar to that shown by gangliosides and phosphatidylinositol.

Animals↗

Interpersonal tactics and communicative strategies of Anglo-American and Mexican-American mildly mentally retarded and nonretarded students.

In this investigation, we compared the preferred interpersonal tactics of mildly mentally retarded Mexican-American and Anglo-American children in an experimental social problem-solving situation. Sixty subjects were divided into four equal groups based upon ethnicity (Mexican-American or Anglo-American) and educational status (mildly mentally retarded or nonretarded). Results indicated that although there were no ethnic group differences, differences in preferred problem solving strategies were demonstrated by mentally retarded and nonretarded children. Overall, nonretarded children tended to utilize strategies such as cooperation and temporary withdrawal more often than mentally retarded children.

Child↗

Referential communication skill levels of moderately mentally retarded adolescents.

Referential communication skills of moderately mentally retarded adolescents (20 speaker-listener dyads) were investigated. In Study 1, subject performance on referential communication activities divided into three skill levels requiring sampling, comparison, and critical-features analysis was examined. Degree of idiosyncratic messages communicated by retarded speakers was investigated in Study 2. Listening competence of retarded and adult listeners was compared in Study 3. Retarded subjects did consistently better on referential communication tasks requiring only sampling than on tasks requiring comparison or critical analysis. Referential communication messages provided by retarded speakers did not have greater meaning to themselves than to others. Finally, retarded listeners and adult listeners did not differ significantly in their ability to utilize the information given by retarded speakers. Implications of the findings for the study of the social communications of retarded children were discussed.

Adolescent↗

A comparison of two Spanish tests of receptive language.

Twenty Spanish-speaking Mexican-American children were administered the receptive portion of the Screening Test of Spanish Grammar (STSG) and the Spanish version of the Test of Auditory Comprehension of Language (TACL). The correlation obtained between the two tests was not statistically significant. The correlation obtained between 24 syntactical items common to both tests was also not statistically significant. The probable reasons for the nonsignificant correlations obtained are discussed. In addition, a detailed critique of the Spanish version of the TACL is presented.

Child↗

[Giant subarachnoid cysts due to neurocysticercosis: two cases reported fro a rural area in Extremadura].

INTRODUCTION: Neurocysticercosis is the commonest cerebral parasitosis. The most recent cases reported in Spain have occurred in patients from endemic countries. The formation of giant subarachnoid cysts (GSC) is an uncommon complication of neurocysticercosis and its treatment is the subject of debate. We report two cases seen recently in the Valle del Jerte, a rural district in Extremadura. CLINICAL CASES: Case 1. A 64 year old man had had complex partial crises (CPC) since 1985. In 1987 he was diagnosed as having neurocysticercosis with parenchymatous cysts and treated with praziquantel. In 1996, on CAT and MR a left frontal GSC was diagnosed and also two parenchymatous active cysts. The cyst was removed surgically and he was subsequently treated with albendazol. Case 2. A 72 year old man had generalized crises and CPC since 1970. In 1987 and 1991 on CAT and MR several parenchymatous lesions compatible with neurocysticercosis were seen. In 1997 he presented with headache and subacute cognitive impairment. On CAT and MR a left temporal GSC was seen with several active parenchymatous lesions. The patient was treated with albendazol and dexamethasone. Both patients improved, although radiological resolution of the GSC in case 2 took a year. CONCLUSIONS: Neurocysticercosis is a condition still present in Spain. GSC respond to treatment with albendazol, whilst surgical treatment is the best option when severe intracranial hypertension occurs.

Aged↗