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Biomedical subjects

R Rutowski

Publications and source records attributed to R Rutowski.

At least 19 recordsLinked to original sources

Neurotizations by means of the cervical plexus in over 100 patients with from one to five root avulsions of the brachial plexus.

In the years 1982-1991, we treated over 100 patients with avulsion of from one to five roots in perinatal (n = 21) and traumatic (n = 81) lesions of the brachial plexus. Based on the clinical diagnosis and the surgical findings, we divided all operated patients into four groups: 1) avulsion of all roots or avulsions and disruption of the rest of the brachial plexus; 2) avulsion and disruption of one to four roots and preservation of some elements of the brachial plexus with fibrotic changes; 3) avulsion and disruption of one to three roots, with some elements showing no macroscopic changes; and 4) children with perinatal brachial plexus palsy. In cases of root avulsion, we performed neurotization from the cervical plexus, the accessory and intercostal nerves. In patients with one to three root avulsions, we have performed selective neurotization for 3 years. The best results were obtained in groups 3 and 4, but some improvement was also noted in the other groups.

Adolescent

[Attempts at modification of the polyester vascular prosthesis].

Polyester vascular bilaterally velour prostheses produced by the Enterprise of Medical Products TRICOMED in Lodz were modified through: putting negative electric charge on the internal surfaces of prostheses; additional cleaning with ethanol; covering of the surfaces of prostheses with silicone preparation; two-sided covering of the surfaces of prostheses with collagen by the radiative method; covering of the surfaces of prostheses with chitosane. Laboratory investigations, investigations of hemolytic and toxic effects of aqueous as well as experimental investigations has been carried on piglets. During these investigations it was observed that the carried preparations caused multiple increase of electrical conductivity of proper and dry remnant after evaporation of the aqueous extracts. Hemolytic and toxic effects were not observed. In radiological and pathomorphological investigations it was observed that none of the preparations used for modification of vascular prostheses influenced improvement of their biological properties. In comparison with the initial prostheses DALLONR these prostheses evoked a greater reaction of tissues which was manifested with a thick internal layer causing narrowing of the lumen of the section with prosthesis or closing it. A small improvement of the biological properties of the prostheses were achieved after cleaning them with methanol. However, this improvement is so small that it does not justify changes in the existing technology.

Animals

[Absorption of chitosan applied to polyester discs in rats after implantation].

Experiments have been made on white rats implanting polyester blocks covered with chitosan into the peritoneal cavity and to the abdominal wall skin. Before implantation the material was sterilized with ethylene oxide or radiation. The animals were subjected to autopsy 3, 7, 14, 21, 25, 30, 35, 40, 45, 50, 55 and 60 days after implantation with macroscopic and microscopic evaluation. On the basis of the carried out experiments it was stated that the disintegration of chitosan proceeded not uniformly. The resorption time of chitosan oscillated in the range of 45-60 days and it was accompanied by rather strong specific inflammation process. It was characterized with fibrin effusion and with appearance of multi-flapped neutrocytes. Essential distinctions in the resorption process of depending on the sterilization mean of the blocks as well as on the place of implantation were not stated.

Abdominal Muscles

[Biocorundum--a new/type of poreless ceramic material of aluminum oxide for the manufacture of the elements of hip joint prosthesis. Biological and technological studies].

The Institute of Refractories Materials in Gliwice undertook researches in the field of technology of a new ceramic material of aluminium oxide for production of coxal joint endoprostheses. A poreless ceramic material of high chemical purity and density and required microstructure and good resistance to fracture, was achieved. The new ceramic material was called Biocorundum. By means of a similar technology also series of samples were produced for testing the biocompatibility of the material. Biological studies were carried out in the Department of Experimental Surgery and Biomaterials Research, Chair of Traumatologic Surgery, Medical Academy of Wroclaw. The studies comprised: 1. laboratory and toxicological tests in vitro of water extracts, 2. pathomorphological studies after intramuscular, peritoneal and intra-bone implantation of samples of the material in rats and piglets, 3. ultrastructural scanning studies of the implantation in rats and pigs and after 3- and 6-months long keeping in the Ringer solution. Preliminary studies and biological studies in vitro have shown a complete conformity of the material with the requirements. Tissue reactivity was studied on 36 Wistar rats. By pathomorphological studies a systematic macroscopic and microscopic estimation was possible. They have shown only minimal tissue reactivity to biocorundum implantation. In experimental studies on 14 piglets the biocorundum grafts were implanted into the tibia epiphysis for 3- and 6-months. Clinical, pathomorphological and X-ray studies were carried out. In all cases the Biocorundum grafts healed without any complications. On the basis of pathomorphological studies, the tissue reactivity around the grafts were estimated as minimal. This shows a high biocompatibility of the ceramic material. In X-ray studies were observed around the grafts small osteosclerotic changes and periosteum stratification. These changes resulted after surgical interventions in quickly growing piglets. Complementary studies of the surface of the material by scanning microscopy after 3 months long implantation and after 3 months long contact with the Ringer solution did not show any changes in comparison with the surface of the initial samples. After 6 months long implantation in individual samples rounding of the ceramic material grain edges were found, which could result from biological corrosive power. This agree with the findings of other studies on other ceramic aluminium oxide materials. The achieved results of complex studies of biocompatibility of the new poreless material developed in Poland--Biocorundum--have shown its complete biological suitability for production of elements of osteoarticul

Aluminum

Radiosterilized polyester knitted nets Dallop.

Polish surgical polyester knitted nets Dallop sterilized by radiation were implanted and tested on Wistar rats. The results of the experimental evaluation are positive and lead to the conclusion that the Dallop radiosterilized polyester nets may be used in humans. The evaluated knittings fulfill the most up-to-date biological requirements and may be utilized as implantation material for plastic and reconstructive surgery.

Abdomen

[Physical and biological examinations of polyester electret foil. Preliminary report].

The results of tissue reaction to polyester thermoelectret foil samples are evaluated. The electrostatic measurement of the foils was performed before implantation. The experimental animals were divided into four groups depending on the surface charge density of the foils. The autopsy of the animals was performed three days after the operation. The tissues of close contact to the foil were examined under the microscope and the electrostatic measurement of the foils.

Animals

Basic studies on autogenized and lysophilized vascular prostheses.

In an effort to improve vascular prostheses, basic studies on tissue-alloplastic prostheses according to a new conception were performed. A medical polyester yarn was used for the construction of three types of prostheses with different mesh and high porosity. The prostheses were autogenized on silicon rods and then lyophilized, resulting in their full intraoperative impermeability, but high biological permeability and antithrombogenicity. Vascular prostheses of this type fulfill many of the requirements of a so-called ideal prosthesis. Analysis of the test examinations provides a basis for elaborating principles for the preparation and production of new tissue-alloplastic prostheses for clinical purposes.

Bacterial Infections

[Clinical study of resorbable surgical sutures. A suggestion].

There has been attempted in the Institute of Surgery, Wrocław Medical School, in 1975 the clinica study with the purpose of comparative evaluation of two kinds of tissue-resorbable surgical sutures, namely catgut and polyglycolic acid threads. To standardize the basic methods of clinical examination to be followed by teams of experts, basing on literature data and own experience, a proposition was elaborated including indications and methods of choosing the groups of resorbable and non-resorbable threads, aseptic demands, and intraoperative, postoperative and laboratory examinations.

Biological Products