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Biomedical subjects

R Rylander

Publications and source records attributed to R Rylander.

At least 199 records · Page 11Linked to original sources
PubMed1977

Studies on humans exposed to airborne sewage sludge.

A clinical investigation was made among workers in a sewage treatment plant and age matched controls not exposed to sewage. Acute incidences of fever and eye symptoms were found in about 50% of the exposed population. Serum immunoglobulins, white blood cells and thrombocytes were elevated in the exposed group. A higher percentage of increased levels of C-reactive protein and fibrinogen degradation products was found in the exposed group. Although no definite cause-effect relationship can be established the responsible agent in the environment could well be endotoxins.

Air Pollution↗
PubMed1977

Airborne micro-organisms and prevalence of byssinotic symptoms in cotton mills.

The concentration of airborne microbes, their endotoxins and the prevalence of byssinotic symptoms among workers were measured in the cardrooms of seven cotton spinning, a wool spinning and two cotton waste mills and in a dusty workroom of a group of five willowing mills, a tea-packing plant and a pipe tobacco factory. The concentration of microbes cultured on endoagar plates were found to correlate with byssinosis prevalence (r greater than 0.95, P less than 0.001). The concentration of nutrient agar microbes correlated with prevalence less well (r greater than 0.77, P less than 0.01) and that of fungi and endotoxins not at all.

Air Microbiology↗
PubMed1976

Acute inhalation toxicity of cotton plant dusts.

The number of free lung-cells was studied in guinea-pigs after acute exposure to extracts of various cotton dusts. A good correlation was found between the increase in number of leucocytes in the airways and the number of Gram-negative bacteria in the different dusts. Experiments using the Shwartzmann reaction and the Limulus titration test demonstrated a relationship between the content of different endotoxins in the dusts and the pulmonary reaction. A model for the acute exposure effects after exposure to cotton dust is proposed.

Animals↗
PubMed1975

Bacterial contamination of organic dusts: effects on pulmonary cell reactions.

The influence of water extracts from different organic dusts on the number of free lung cells was studied in short-term exposure experiments. A large increase in the number of leukocytes was found 24 hours after exposure to extracts from cotton and hay. The number of macrophages was not affected. The increase was greater when the dusts were incubated at 37 C and 100% relative humidity prior to the preparation of the extract. This procedure caused an increase in the number of bacteria. When different bacterial species were studied endotoxin-producing strains were found to cause the largest effect.

Animal Feed↗
PubMed1975

Pulmonary cell response patterns after exposure to airborne bacteria.

The free lung cells obtained with a lavage technique were studied in guinea-pigs exposed to an aerosol of E.coli, K. pneumoniae or B.subtilis. An increase in the number of polymorphonuclear leucocytes was found 5-48 hours after exposure to E.coli and B.subtilis. The clearance of a mixture of viable and radioactively labelled E.coli was studied in animals with a naturally present or artificially induced high leucocyte level in the lungs. It was found that animals with the higher leucocyte number cleared the inhaled bacteria faster.

Aerosols↗
PubMed1973

The effect of saline on the eye irritation caused by swimming-pool water.

In laboratory experiments the acute eye irritation produced by exposure to tap water was not significantly increased when chlorine compounds were added to the water at concentrations of 1 mg./l. The greatest irritation was produced by 2 mg. Cl(2)/l. as NH(2)Cl. The addition of NaCl at concentrations above about 0.5% abolished the irritant effect of tap water, and prevented irritation even when 1 mg. Cl(2)/l. was present.In a field experiment involving two swimming baths, one with fresh and the other with saline water (0.5% NaCl), eye irritation in the saline bath was significantly lower than in the freshwater bath only when the swimming time did not exceed 30 min.

Adolescent↗