Biomedical subjects
R S Barsoum
Publications and source records attributed to R S Barsoum.
Plasma immunoreactive insulin (IRI) and glucose tolerance in bilharzial hepatic fibrosis.
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Renal biopsy in Schistosoma-Salmonella associated nephrotic syndrome.
Percutaneous needle biopsy of the kidney on eight nephrotic patients with Schistosoma mansoni and chronic Salmonella paratyphi A infection showed diffuse proliferative glomerular change in all biopsies. Capillary basement membrane was normal. Diffuse granular deposits were detected in the glomerular mesangial cells by direct staining with fluorescein labelled anti-IgG anti-IgM. No fluorescence was obtained with rabbit anti-Salmonella paratyphi A. After treatment with ampicillin and niridazole, a reduction of cellular proliferation and mesangial matrix expansion was observed. Simultaneously following treatment there occurred a dramatic clinical improvement with cessation of proteinuria and a return of plasma protein levels and serum complement (C3) to normal values.
The ileocecal bladder: a new method for urinary diversion after radical cystectomy (a preliminary report).
Ten patients underwent radical cystectomy and ileocecal bladder reconstruction for carcinoma of the bladder. The ileocecal region was used as an artificial bladder, its valve protecting the kidneys from back pressure exerted by the external urethral sphincter. The ureters were anastomosed to the ileal part and the cecum was anastomosed to the prostatic urethra in 7 men and to the bladder neck in 2 women and 1 man. Two patients died postoperatively. All patients had perfect control of micturition during the day. Those in whom the bladder neck was preserved were also fully continent at night. The remaining patients had a minor degree of nocturnal enuresis with only a few drops of urine voided involuntarily during sleep. All patients feel the desire to void when the bladder is full. Voiding cystograms in all patients did not reveal reflux in the ureters. IVP's done up to 11 months postoperatively showed preservation and improvement of kidney function and configuration. Followup cystometric studies and serum electrolyte determinations are under investigation.
Assessment of the correlations of diabetic vascular complications.
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Plasma immuno-reactive insulin (IRI) and peripherel glucose utilization in bilharzial patients with impaired renal functions.
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Post-dialysis urea rebound.
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Long-term intermittent haemodialysis in Egypt.
The pattern of mortalities from genitourinary diseases in Egypt was analysed from recent official figures. On the basis of certain assumptions concerning etiology, age, and geographical distribution, it was estimated that 37.7 per million of the general population would benefit from regular dialysis treatment, though the facilities available will permit only 5% of these subjects to receive treatment in 1975. As other diseases and conditions are much more prevalent, no great relative increase in dialysis facilities in Egypt is anticipated in the near future. A computer-controlled plan is suggested for organizing regular dialysis treatment at the national level to ensure an appropriate choice of medically suitable subjects of highest value to the community. Means of reducing the need for dialysis by minimizing the incidence of terminal chronic renal failure and of making best use of the available facilities are discussed.
A biological method for diagnosis of different forms of arterial hypertension.
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