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Biomedical subjects

R S Corfman

Publications and source records attributed to R S Corfman.

8 recordsLinked to original sources
PubMed1992

Falloposcopy.

This review discusses advances in falloposcopy over the past 10 years. Refinements in instrumentation, including fiberoptics, have allowed visualization of the endosalpinx, a portion of the reproductive tract that has evaded endoscopic evaluation. A coaxial system of falloposcopic placement may give way to a linear everting catheter that does not require hysteroscopic guidance. Tubal endoscopic applications are discussed, including correlating hysterosalpingogram findings with those findings at salpingoscopy. Endosalpingeal changes can be quantitated in the presence of hydrosalpinges, and possibly with endometriosis. A scoring system to measure changes has been described. Using this scoring system, endosalpingeal findings at salpingoscopy have been compared with histologic and electron microscopic findings.

Endoscopes↗
PubMed1991

Advances in gynecologic imaging and intervention.

Advances in diagnostic imaging of the female genital tract facilitate characterization of many pelvic masses. Preoperative assessment of gynecologic malignant tumors provides information that may alter the surgical approach or timing of radiation therapy. Image-guided biopsy accurately confirms recurrent malignant lesions. Transcervical techniques have improved diagnostic assessment of infertile couples; thus, effective and inexpensive treatment options can be offered. Postoperative complications of gynecologic procedures can be detected with imaging, and many can be treated with image-guided techniques.

Female↗
PubMed1991

Laparoscopic use of sutures.

The ability to do laparoscopic suturing or stapling techniques effectively greatly adds to the level of comfort and performance of the endoscopic surgeon. Each of us is driven by the desire to do a given procedure at laparoscopy just as well as we could at laparotomy. If we cannot, we question whether or not it should be done endoscopically by us. By being able to perform the techniques just described, surgeons can deal effectively with many situations which might otherwise keep them from providing an endoscopic service to their patients. Finally, we must weigh carefully the pros and cons of placing any sutures at all in a given situation.

Female↗
PubMed1989

Endometriosis-associated infertility. Treatment options.

Formulating a treatment plan for infertility associated with endometriosis is difficult due to the lack of a cause-and-effect relationship between the disease and infertility. Several molecular and cellular mechanisms have been postulated as playing roles in endometriosis-associated infertility; they are reviewed here. Several medical and surgical treatment options are discussed, including danocrine, medroxyprogesterone acetate and gonadotropin releasing hormone agonists. A combined medical and surgical approach and occasional expectant management remain the treatments of choice.

Endometriosis↗
PubMed1988

Indications for hysteroscopy.

A description of current indications for hysteroscopy is presented, including a review of the literature. Emphasis is placed upon indications that are felt to be useful in the diagnosis and treatment of common gynecologic problems, including abnormal uterine bleeding, infertility, recurrent pregnancy wastage, and removal of intrauterine foreign bodies.

Endoscopy↗
PubMedDate not supplied

Analysis of chromatin proteins from human placenta.

Low-salt extracts of chromatin from human term placenta have been examined for the presence of the high mobility group (HMG) proteins. Based upon salt-dissociation characteristics, solubilities in trichloroacetic acid and electrophoretic behaviour on sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) and non-equilibrium pH gradient gel electrophoresis (NEPHGE), each of the HMG proteins is present, including HMG-1, -2, -E, -14, and -17. A remarkably large amount of HMG-E is present in term human placenta. Additionally, a protein not previously recognized, which we designate HMG-PL, is present in term placenta. Electrophoretic comparison of the HMG proteins from placentae of varying gestational age, using NEPHGE, demonstrates that all of the placental HMG proteins exhibit multiplicity, reminiscent of chicken erythrocyte HMG proteins. Specifically, we found HMG-E to be unaltered in amounts relative to HMG-1 and -2 in placentae varying from 20 to 40 weeks of gestation. HMG-PL, however, is differentially expressed, increasing in amounts as gestation proceeds past 34 weeks. HMG-PL was purified and subjected to amino acid analysis. Its composition supports the notion that HMG-PL is a member of the HMG-1 family.

Amino Acids↗