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Biomedical subjects

R S Galonsky

Publications and source records attributed to R S Galonsky.

4 recordsLinked to original sources

Charcoal-induced lipid reduction in uremia.

Charcoal, in divided oral doses totalling 35 g/day, was administered to six patients with renal insufficiency (creatinine clearance of 0 to 45 ml/min). Significant (P less than 0.01) reductions in serum cholesterol and triglycerides were observed in the three most hyperlipidemic patients. Maximal decreases in charcoal responders, as compared with control values, were for cholesterol (43%, 23.4% and 40.4%) and for triglycerides (76%, 60.3% and 64.3%). None of the patients showed altered concentrations of BUN, serum creatinine, uric acid, or vitamin A. Because of its safety and the profundity of its hypolipidemic action, it is suggested that charcoal may find applicability in the management of azotemic diabetic and nephrotic hyperlipidemia.

Adult↗

Mobilizing hemodialysis.

In collaboration with Christopher R. Blagg at the University of Washington and John F. Sullivan at Cornell College of Medicine, we have conducted a trial of travel dialysis using the Friedman-Hutchisson suitcase system. A total of 122 location dialyses were performed by 18 patients on 22 trips in Europe, Canada and the United States. Evolutionary modifications in the system have resulted in a device with broad patient acceptance which is now being prepared for manufacture in quantities expected to meet a growing demand.

Humans↗

Field trial of compact travel dialysis system.

To increase mobility for home hemodialysis patients, a portable, light weight hemodialysis system has been bench and field tested. The combination of a 21 L dialysate reservoir and small, high speed blood and dialysate pumps has permitted the entire system to be contained in a twenty two pound, 22 X 13 X 6 inch aluminum suitcase. Initial evaluation in hospitalized patients has shown the system to be safe and efficient. Acceptable clearances of creatinine and urea are maintained throughout a five hour dialysis by changing the bath at 120 and 210 minutes. Successful application of the system in travel by 3 patients, who perfomed a total of 12 dialyses in their hotel rooms while on vacation, indicates the broad potential of the new system.

Adult↗