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Biomedical subjects

R S Koplin

Publications and source records attributed to R S Koplin.

5 recordsLinked to original sources
PubMed1990

Chronic postoperative endophthalmitis from Staphylococcus aureus.

We recently treated a patient with chronic postoperative endophthalmitis caused by Staphylococcus aureus, which usually presents with a fulminant clinical course. Because of the chronic course, the initial treatment was high dose steroids followed by lensectomy and vitrectomy. However, this was not effective, and intravitreal antibiotics and steroids were ultimately required. We now recommend that in patients with chronic postoperative inflammation unresponsive to high dose steroids, intraocular cultures followed by injection of intraocular antibiotics be considered.

Aqueous Humor↗
PubMed1990

3-D corneal modeling system.

New surgical procedures have been introduced recently that provide refractive correction to replace the use of eyeglasses or contact lenses. The procedures involve reshaping the cornea to compensate for the optical anomalies of astigmatism and nearsightedness. Although thousands of operations are currently performed in the U.S., there are no instruments available for monitoring the results. Thus, a critical need has arisen to inspect and measure the cornea's surface both before and after surgery. In this paper an instrument is presented which provides a detailed topographical model of an individual's cornea. The method uses a novel structured light source. The cornea is modeled as a convex mirror which forms a virtual image of the structured light source. A single image is recorded from the patient's cornea. The depth is obtained from triangulation between the acquired image and a reference image of a sphere. The reconstruction of the depth map is complicated by the fact that the magnification used in recording the image varies with the radius of curvature of the cornea. An iterative method is presented which solves for the radius of curvature despite the variation in magnification. The virtual image is digitized and the instantaneous curvature of the cornea is obtained. The instantaneous curvature is displayed in units of optical power (diopters). This display provides the ophthalmologist or optometrist with the essential optical properties of the cornea.

Cornea↗
PubMed1988

Corneal modeling.

The Corneal Modeling System is presented as an integrated instrument system designed to give the corneal surgeon the capability of measuring and designing alterations of corneal shape that are comparable to the computer-aided design (CAD) capability used in aerospace design and other industries. The system provides realtime digital video image acquisition using a high-resolution, cylindrical photokeratoscope and scanning laser slit lamp. From these digitized images, the system's computer derives topographic and pachymetric information in sufficient density to produce a continuous mathematical function that represents both the front and the back surface of the cornea. The mathematical model may then be sampled in as many points as the clinical application requires, in the form of either computer graphics or a numerical data stream to control precision machinery to make contact lenses or tissue lenses. Representative computer graphics of normal and pathologic corneal conditions are presented.

Cornea↗