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Biomedical subjects

R S Kurban

Publications and source records attributed to R S Kurban.

9 recordsLinked to original sources
PubMed2000

Collagen vascular diseases: cutaneous manifestations in ophthalmology.

PURPOSE: To describe the effects of collagen vascular diseases on the eyelids and periorbital tissues. METHODS: Retrospective review of dermatologic pathology slides at Massachusetts General Hospital and eye pathology slides at Massachusetts Eye and Ear Infirmary, Boston, Massachusetts. RESULTS: A spectrum of dermatologic manifestations of collagen vascular diseases was observed, affecting the eyelids and periorbital region. CONCLUSIONS: Collagen vascular diseases may present complicated diagnostic and clinical challenges for the practicing ophthalmologist. Familiarity with the cutaneous periocular manifestations of these diseases may facilitate early recognition, diagnosis, and ophthalmologic intervention where necessary.

Collagen Diseases↗
PubMed1993

Common skin disorders of aging: diagnosis and treatment.

The incidence of skin disorders increases with age because of changes in skin structures and a lifetime accumulation of environmental insults. Photoaging, resulting from exposure to harmful ultraviolet wavelengths in sunlight, is responsible for many common skin disorders, from wrinkles to melanoma. Older patients also see their physicians with complaints of various types of dermatitis, including contact and seborrheic. Although skin disorders vary in severity, they all adversely affect an older patient's health and/or quality of life. Early recognition, prevention, and treatment of skin diseases by the primary care physician is therefore an important element in the overall care of the middle-aged and older patient.

Age Factors↗
PubMed1992

Anorectal melanoma. A case report and brief review of the literature.

Anorectal melanoma in an uncommon tumor that has a poor prognosis. We present a case of anorectal melanoma and review the literature pertaining to prognosis and treatment. Although no controlled trials of treatment of anorectal melanoma have been done, the evidence suggests that conservative excision confers comparable survival with less morbidity than radical surgery.

Aged↗
PubMed1992

Occurrence of melanoma in "dysplastic" nevus spilus: report of case and analysis by flow cytometry.

We report a case of melanoma arising in a large nevus spilus. On histologic examination, the nevus spilus had diagnostic features of melanocytic dysplasia. Further characterization by flow cytometry showed DNA-aneuploidy within the melanoma as well as in one of the darker pigmented papules within the nevus spilus. The significance of this finding and a review of melanomas originating in nevi spili are presented.

Adult↗
PubMed1991

Cutaneous cysts lined by nonsquamous epithelium.

This article provides a clinicopathological review of cutaneous cysts with a nonsquamous epithelial lining. Particular histologic features are presented to better define each of the entities in the differential diagnosis.

Cysts↗
PubMed1990

Histologic changes in skin associated with aging.

This is a review of histologic changes noted in the skin of elderly individuals. Among the epidermal changes associated with skin aging are a flattened dermal-epidermal junction, giving the appearance of atrophy and cellular heterogeneity. The melanocyte density declines slowly, and the Langerhans cells decrease in number with advancing age. Among the dermal changes are attenuation in the number and diameter of elastic fibers in the papillary dermis, an increase in number and thickness of the same fibers in the reticular dermis, and a coarsening of collagen fibers with an increase in density of the collagen network. A decrease in the dermal cell population as well as a functional decline in glandular activity are also noted with intrinsic aging. A decline in hair number, rate of growth, and diameter, along with a slowing of the rate of growth of nails, have been well documented with progressive aging.

Adult↗
PubMed1988

Neutrophilic eccrine hidradenitis in the absence of an underlying malignancy.

Neutrophilic eccrine hidradenitis is an entity previously reported to occur in association with malignancy and chemotherapy. We report a case of clinical and histopathologic findings characteristic of neutrophilic eccrine hidradenitis occurring without apparent underlying disease. In addition, the only medication this patient was taking was acetaminophen. Neutrophilic eccrine hidradenitis appears to represent a reaction pattern without specificity for underlying disease or inciting agent.

Acetaminophen↗