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Biomedical subjects

R S Pinto

Publications and source records attributed to R S Pinto.

At least 37 records · Page 2Linked to original sources

Intravenous digital subtraction angiography in the investigation of intracranial disease.

Eighty-six patients who presented with a variety of intracranial lesions were examined with intravenous digital subtraction angiography (IV-DSA). A grading system was used to evaluate the ability of IV-DSA to answer specific diagnostic questions regarding intracranial tumors, vasospasm following subarachnoid hemorrhage, lesions of the sella, dural sinus occlusion, and post-therapeutic embolization. Eighty-four per cent of the examinations provided clinically useful information. In 15% of the cases limited but useful information was obtained; only 1% of the examinations provided no useful information. We conclude that IV-DSA can routinely provide useful information in the evaluation of the variety of intracranial lesions described above.

Angiography↗

The tethered spinal cord: diagnosis by high-resolution real-time ultrasound.

High-resolution real-time ultrasonography of the lumbosacral spine was performed in 10 control patients and in six patients with suspected spinal dysraphism. The spinal cord was readily visualized in both groups. Lack of ossification of the posterior arch of the spine in normal infants and the presence of a bony defect in patients with spina bifida permit sonographic investigation of the spinal canal and its contents. It is concluded that the diagnosis of spinal cord tethering can be established rapidly by high-resolution real-time ultrasonography, which may be used in screening patients with suspected occult spinal dysraphism.

Humans↗

Dynamic CT scanning for visualization of the parasellar carotid arteries.

Evaluation of patients before transsphenoidal hypophysectomy for large intrasellar mass lesions has required bilateral internal carotid artery angiography. Using intravenous injection of contrast medium, a method has been developed to visualize the parasellar carotid arteries with rapid sequence sequential computed tomographic scanning. In 18 patients, the cavernous segments of the internal carotid arteries were well seen in 27 of 28 instances with technically complete examinations. The vascularity of the mass lesions and vascular encasement was also demonstrated.

Adenoma↗

Small acoustic neuromas: detection by high resolution gas CT cisternography.

Experience with 81 gas computed tomography (CT) cisternography procedures in 79 patients in searching for acoustic neuroma is reported. Twenty-one tumors, four exclusively intracanalicular, were demonstrated after standard contrast-enhanced CT was negative. Fifty-five examinations were negative; four were inconclusive. The high resolution scanner with digital localization and reconstruction zoom capability greatly improved image detail. In nine of the 12 normal patients examined with it, the intracanalicular bundle was demonstrated. Substitution of carbon dioxide for air greatly reduced the morbidity of acute post-spinal tap headache. The procedure takes 30--45 min and can be performed on an outpatient basis. It is recommended as the procedure of choice when standard CT is negative in subjects clinically suspected of having acoustic neuroma.

Humans↗

Giant intracranial aneurysms: rapid sequential computed tomography.

Giant intracranial aneurysms often present as mass lesions rather than with subarachnoid hemorrhage. Routine computed tomographic (CT) scans with contrast material will generally detect them, but erroneous diagnosis of basal meningioma is possible. Rapid sequential scanning (dynamic CT) after bolus injection of 40 ml of Renografin-76 can conclusively demonstrate an intracranial aneurysm, differentiating it from other lesions by transit-time analysis of the passage of contrast medium. In five patients, the dynamics of contrast bolus transit in aneurysms were consistently different from the dynamics in pituitary tumors, craniopharyngiomas, and meningiomas, thereby allowing a specific diagnosis. Dynamic CT was also useful after treatment of the aneurysms by carotid artery ligation and may be used as an alternative to angiographic evaluation in determining luminal patency or thrombosis.

Carotid Arteries↗

The value of dynamic scanning.

Dynamic CT is a proven alternative to angiography in the assessment of parasellar lesions. Characteristics of the tumor, such as vascularity or cystic regeneration, are easily demonstrated. Dynamic CT is able to diagnose conclusively an intracranial aneurysm and to follow the therapeutic course after ligation of the carotid artery. The application of dynamic CT to cerebrovascular disease is limited by the lack of subsecond sequencing in fragmentation scans. Its importance in documenting the patency of the cervical internal carotid artery that appears to be occluded angiographically cannot be overstressed.

Adult↗

Computed tomography in the diagnosis of eosinophilic granuloma.

The clinical, radiographic, and computed tomographic (CT) findings in three proven cases of eosinophilic granuloma are presented. Because eosinophilic granuloma has typical appearance on CT, this method is more useful than plain film tomography in diagnosing this lesion.

Adolescent↗

Computed tomography of arachnoid cysts.

The typical CT appearance of intracranial arachnoid cysts may obviate additional neuroradiological procedures. Ventriculography using water-soluble contrast media may differentiate a suprasellar arachnoid cyst from a dilated third ventricle. Twelve cases are presented.

Adolescent↗

Correlation of computed tomographic, angiographic, and neuropathological changes in giant cerebral aneurysms.

Giant aneurysms involving or adjacent to the circle of Willis exhibit three CT patterns: nonthrombotic, partially thrombotic, and completely thrombotic. Partially thrombotic aneurysms have the most specific pattern, consisting of a "target" configuration on the post-contrast scan. Ring calcification of the wall or mural thrombus is frequently observed in partially or completely thrombotic aneurysms. Calcification is not seen in nonthrombotic lesions. Angiographic and neuropathological findings are correlated with the CT findings.

Angiography↗

Role of computerized tomography in the diagnosis of acoustic neuromas.

Computerized tomography has manifest usefulness in the roentgenologic identification of intracranial masses, and acoustic neuromas are no exception. Nonetheless, traditional roentgenographic examinations for the workup of acoustic neuromas should not yet be completely discarded in favor of this new modality. Computerized tomography scanning is an insensitive and unreliable technique for delineating the size and configuration of the internal acoustic canals. With current technology, it will not reliably show neuromas less than 1.5 cm in cross-sectional dimension. Technical artifacts may also contribute to false-negative and though rare to false-positive findings. The false-negative rate will be unacceptably high in the presence of small lesions if this technique is treated as a definitive examination rather than a screening one. Though uncommon, it may also be negative in the presence of relatively large lesions.

Humans↗

Computed tomography in pediatric diagnosis.

The use of computed tomography has revolutionized the evaluation of the neurologically ill child. This safe and noninvasive procedure may be done on an outpatient basis, eliminating for many the complications that may occur from invasive neuroradiologic procedures. Computed tomography is of particular value in the assessment of intracranial neoplasms, hydrocephalus, and vascular disease. Further advancements are expected in the technology of computed scanning and in its diagnostic use in the rest of the body.

Brain↗