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R S Pozzi-Mucelli

Publications and source records attributed to R S Pozzi-Mucelli.

42 records · Page 3Linked to original sources

[Comparative evaluation of echography, computerized tomography and magnetic resonance imaging in the diagnosis of hepatocellular carcinoma in cirrhotic patients].

The contribution of US, CT, and MR imaging was investigated in 25 cirrhotic patients with hepatocellular carcinoma. The following parameters were considered: lesion detection, site and size of the lesion, daughter nodules, location and/or infiltration of intrahepatic vessels, patency of portal vein and collateral vessels, signs of chronic liver disease, steatosis, ascitis, and lymphadenopathy. Our results confirm the value of US, which also allowed lesion biopsy in all cases. CT was as accurate as US in detecting the lesion and even superior in demonstrating daughter nodules. MR imaging, with conventional SE and IR sequences, was inferior since it missed 3 lesions due to motion artifacts; moreover, a smaller number of daughter nodules was seen than with CT. The authors conclude that, at present, MR imaging cannot replace US and CT; the latter, if combined with arteriography, using either hydrosoluble or liposoluble contrast agents, gives the best results in the detection of small hepatocellular carcinomas, and especially of daughter nodules which are important factors for planning appropriate therapy.

Carcinoma, Hepatocellular↗

[Modular project of the Picture Archiving and Communication System (PACS). Preliminary clinical experience. II].

In the previous paper in this volume the PAC System installed in the Radiology Department of the University of Trieste has been described and its advantages and limitations have been analyzed, mainly from an operational point of view. This paper deals with the clinical evaluation of the system in ordinary operative conditions. A series of cases with specific characteristics was monitored in order to reveal different performances in both diagnostic process and conclusions using the PACS viewing console (DW) vs. conventional CRT film images on alternators. In a first test, 100 routine (not pre-selected) brain CT cases were independently analyzed by 4 radiologists, each of them giving 2 interpretations of the same case, one based on film and the other on PACS. The data were analyzed by conventional statistical methods, showing a substantial agreement of the results obtained with the 2 modalities. A second test concerned the evaluation of 100 lumbar intervertebral disks by CT, with the same procedure as above. Four radiologists were again asked to decide on film and PACS images about normality, protusion, or herniation of the disks. The results demonstrate the possibility of adequately reporting on the PACS monitor and stress the need of an adequate training period and the efficacy of the image processing capabilities of the system.

Brain Diseases↗

[Ultrasonography in primary hepatic tumors: potentialities, limits and comparison with arteriography (author's transl)].

The echotomographic patterns in 22 patients with hepatic neoplasms are reported and discussed. Ultrasonography has a high sensitivity in detecting the solid echopattern of the tumour and its origin from liver parenchyma; gray-scale B-scan and a meticulous technique are very helpful for this purpose. Echotomography plays an important part in the diagnostic evaluation of this pathology, to better select the patients for more invasive techniques, after the screening procedures, as scintigraphy.

Adenoma↗

[Computed tomography and magnetic resonance in the preoperative staging of the spread of rectal cancer. A correlation with the anatomicopathological aspects].

In order to assess the accuracy of CT and MRI in evaluating the local extent of rectal carcinoma, 22 patients with a rectoscopic diagnosis of rectal cancer were examined before surgery with both techniques. Tumor extent into the perirectal fat, involvement of surrounding structures and local adenopathy were evaluated on both CT and MR images. These findings were compared with the micro- and macrohistologic findings obtained from the surgical specimens. As far as perirectal fat infiltration is concerned, the diagnostic accuracy of CT was 73% and that of MRI was 71%. Sensitivity was 100% for CT and 91% for MRI, while specificity was low for both techniques (45% for CT and 50% for MRI). In evaluating local adenopathy, CT accuracy was 82% and MR accuracy was 90%, with 89% sensitivity for both techniques and 77% specificity for CT and 92% for MRI. The overall accuracy was 59% for CT and 67% for MRI. In agreement with literature data, our study shows a similar accuracy for CT and MRI in evaluating the local extent of rectal carcinomas. Moreover, our results confirm the value of macrohistology in the local staging of rectal carcinoma and its prognostic value, as well as the low specificity of both CT and MRI in evaluating lesion spread into the perirectal fat.

Aged↗