HEMOGLOBIN SOLUBILITY AND ALPHA-CHAIN STRUCTURE IN CROSSES BETWEEN TWO INBREAD MOUSE STRAINS.
In genetic crosses between mouse strains with low and high solubilities of hemoglobin, solubility segregated as a Mendelian unit and appeared to be determined by the alleles controlling alpha-chain structure. New data eliminate close linkage between the alpha-chain locus and genetic markers in linkage groups Ill, IV, XI, XIII, and XVI. Simplified methods are presented for screening differences inalpha-chain peptides and solubility.
Alleles↗