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Biomedical subjects

R S Trompeter

Publications and source records attributed to R S Trompeter.

65 records · Page 4Linked to original sources
PubMed1980

HLA, atopy, and cyclophosphamide in steroid-responsive childhood nephrotic syndrome.

In a study designed to confirm our preliminary report of associations between HLA-B12, atopy, and relapse following cyclophosphamide treatment in steroid-responsive nephrotic syndrome (SRNS), we again found a higher incidence of HLA-B12 in SRNS children (44%) than we did in controls (24%). The association of HLA-B12 with short time-to-relapse after cyclophosphamide treatment of SRNS was also confirmed, but that with atopy in SRNS children was not, though we observed a similarly high incidence of atopy in them as before.

Asthma↗
PubMed1976

Neonatal brain growth during prolonged intravenous feeding.

Little is known about the affects of long-term intravenous nutrition on brain growth and development in low birthweight infants. We report the post-mortem analysis of the brain of an infant born at 32 weeks of gestation who died 10 weeks of continuous intravenous feeding. During this time there was evidence of brain growth while somatic growth was severely restricted. Compared with normal data for brain biochemistry for 42 weeks of gestational age, measurements showed that the brain was small and biochemically immature with the cerebellum and brain stem being particularly affected.

Brain↗
PubMed1976

24-Hour urinary glucose excretion in assessment of control in juvenile diabetes mellitus.

24-Hour urinary glucose excretion was measured in 43 juvenile diabetics during treatment as outpatients. In 20 children studied twice over 1-3 months there was good correlation between glucose excretion on each occasion. Subdivision of the collections into the periods 08 therefore 00-20 therefore 00 and 20 therefore 00-08 therefore 00 hours gave slightly less consistent results with correlation coefficients of 0 therefore 83 and 0 therefore 80, respectively, between the results of the repeat tests. In 37 prepubertal children, 24-hour glucose concentration and height velocity over the previous year were compared, and a highly significant negative correlation found. 10 of the 12 children with glucose excretion greater than 40 g/d had height velocities more than 1 SD below the mean for age, while only 2 of the 25 subjects excreting less than 40 g/d had height velocities more than 1 SD below the mean. The results indicate that estimation of 24-hour urine glucose excretion can be a useful index for monitoring treatment and that subdivision of the total collection may be of value in selecting the most suitable insulin regimen for the patient.

Adolescent↗