PubMed Health⌕ Search

Biomedical subjects

R Sabates

Publications and source records attributed to R Sabates.

16 recordsLinked to original sources
PubMed1989

Macular changes after retinal detachment surgery.

We studied 175 eyes of 175 patients who had successful repair of primary rhegmatogenous retinal detachment. Patients were randomly assigned to be treated with cryotherapy and episcleral sponges or with diathermy, scleral dissection, and encircling silicone bands. Fundus photography and fluorescein angiography were performed six weeks after successful reattachment surgery. Macular complications were discovered in 48 (27%) of the 175 eyes. The most frequent changes were cystoid macular edema in 28 (16%) and preretinal macular membrane in 13 eyes (8%). No significant differences in the incidence of cystoid macular edema were observed between diathermy and cryotherapy. Macular detachment, increased duration of macular detachment, cryotherapy, and pseudophakia were identified as risk factors for certain macular complications.

Adolescent↗
PubMed1988

Choroiditis compatible with the histopathologic diagnosis of sympathetic ophthalmia following cyclocryotherapy of neovascular glaucoma.

A 44-year-old man had a blind painful right eye secondary to neovascular glaucoma. Cyclocryotherapy was performed because medical therapy was ineffective in lowering the intraocular pressure or reducing the pain. The eye became comfortable, but 5 months later vision decreased in the left eye. Examination revealed a marked posterior uveitis suggestive of sympathetic ophthalmia. Enucleation of the right eye and corticosteroid therapy were effective in eliminating inflammation in the left eye. Histopathologic examination of the exciting right eye revealed classic signs of sympathetic ophthalmia. This case is particularly unusual because there was no history or evidence of ocular perforation in the exciting eye.

Adult↗
PubMed1987

Metoclopramide as prophylaxis for nausea and vomiting induced by fluorescein.

Fluorescein angiography carries with it a variable incidence of nausea and vomiting. We investigated a method of prophylaxis against this side effect. One hundred patients undergoing fluorescein angiography were pretreated in a double-masked, randomized fashion with either 20 mg of intravenous metoclopramide hydrochloride or an equal volume of normal saline solution. The metoclopramide-treated group demonstrated a statistically significant decrease in the incidence of nausea and vomiting. Eleven (22%) of the control group and three (6%) of the metoclopramide-treated group had this complication. Metoclopramide is an effective drug when used prophylactically in selected patients undergoing fluorescein angiography.

Female↗
PubMed1987

Neodymium: YAG laser treatment of persistent pupillary membrane.

A 16-year-old girl had a cosmetically unappealing persistent iridopupillary membrane in the left eye. Her best corrected visual acuity was 20/60, but this improved to 20/40 with pupillary dilation. Neodymium: YAG laser membranectomy resulted in 20/20 vision. This is the first reported case of persistent pupillary membrane treated with the Neodymium: YAG laser.

Adolescent↗
PubMed1983

Electroretinography in the prognosis and classification of central retinal vein occlusion.

Forty-five patients with a central retinal vein occlusion were divided into three groups: those with venous stasis retinopathy (VSR, n = 27), those with hemorrhagic retinopathy (HR, n = 6), and those with undetermined retinopathy (n = 12). The electroretinogram (ERG) was recorded in all cases. The average b/a-wave amplitude ratio of the single white-flash ERG was 1.67 for the VSR group and 0.70 for the HR group. The ERG responses in the group with undetermined retinopathy helped to assess the degree of retinal ischemia and to further categorize the disorder as either VSR or HR. The b/a amplitude ratio reflected the degree of retinal ischemia and had prognostic value in predicting in which cases neovascular glaucoma may develop. The average b/a ratio in the six cases in which neovascular glaucoma developed was 0.84. This complication did not develop in any patient with a b/a ratio greater than 1. Four patients with low b/a ratios (average, 0.73) were treated with panretinal photocoagulation; neovascular glaucoma developed in none.

Adult↗
PubMed1983

Ocular findings in Alport's syndrome.

6 cases of Alport's syndrome with ocular findings are presented and discussed. 4 cases had bilateral anterior lenticonus, one had retinal changes similar to the flecked retina syndrome and 1 case had posterior polymorphous corneal changes, a previously unreported finding. The varied ocular changes presented here all have in common a pathologic process involving the basement membrane or the specialized epithelium.

Adolescent↗
PubMed1983

Collateral circulation in hemicentral retinal vein occlusion.

The perchance occurrence of a hemicentral retinal vein occlusion in an eye with a lightly pigmented fundus allowed us the opportunity to observe the development and flow dynamics of collateral circulation. We are able to demonstrate an optic disc collateral draining into a choroidal vein, a finding which to our knowledge had previously only been documented histologically. The collateral circulation developed slowly over many months and was not rapid enough to prevent chronic microcystic macular changes.

Aged↗
PubMed1982

Pseudovitelliform macular degeneration.

Forty-two patients with pseudovitelliform macular degeneration (VMD) were studied. The macular lesions were yellow in color, appeared as a slight elevation at the level of the retinal pigment epithelium (RPE), were usually 1/4 to 1/2 disc diameter in size and often showed a round or oval shape. Progression occurred over many years, resulting in a circumscribed atrophic area in the RPE. The lesions in VMD were morphologically similar to those seen in Best's vitelliform dystrophy, but the electrooculogram was normal or slightly subnormal in all cases. The average Lp/Dt ratio in 71 eyes tested was 2.16. There were 31 women and 11 men with a median age of 51 years at initial presentation. Family studies did not reveal other affected members. Long-term follow-up (five years or longer) in ten cases showed that useful vision is retained in at least one eye.

Adolescent↗
PubMed1979

HLA-B7 in presumed ocular histoplasmosis maculopathy.

Sixty-four patients that fulfill the clinical criteria of the presumed ocular histoplasmosis syndrome were typed for common histocompatibility antigens. The clinical criteria included the presence of multiple peripheral punched out choroidal atropic scars, a clear vitreous, and compatible macular disciform lesions in at least one eye. Thirty-four patients were found to have HLA-B7, which is statistically significant at the p less than 0.005 level when compared to a normal population. Though this is statistically significant, other factors must be involved, as there still remain many patients with this clinical picture who do not demonstrate a common histocompatibility antigen.

Gene Frequency↗
PubMed1978

Association of presumed ocular histoplasmosis with HLA-B7.

Thirty-one white patients who fulfilled the clinical criteria of the syndrome recognized as presumed ocular higtoplasmosis were typed for common histocompatibility antigens. These clinical criteria included the presence of multiple peripheral punched out choroidal atrophic scars, compatible macular disciform lesion in at least one eye, and clear vitreous. Seventeen out of 31 patients were found to have HLA-B7, which is statistically significant at the P less than .005 level when compared to a normal population. More patients should be tested to establish this correlation more firmly. Though this is statistically significant, other factors must be involved as there still remain many patients who fulfill the clinical criteria but do not demonstrate a common histocompatibility antigen.

Eye Diseases↗
PubMed1977

Early argon laser photocoagulation of presumed histoplasma maculopathy.

In this study, 66 patients with presumed ocular histplasmic maculopathy and in whom the edge of the neovascular membrane was at least 200 micron from the center of the fovea were selected for treatment with argon laser photocoagulation. They were divided into three groups depending on the time elapsed between the beginning of symptoms and treatment with argon laser photocoagulation. The size of the neovascular membrane, the distance from the center of the fovea, and the presence of hemorrhage in the foveal area were also noted. We found that the most important prognostic factor for best final visual acuity was the interval of time between onset of symptoms and treatment. The study showed that 73.3% (22 of 30) of patients with symptoms of short duration (four weeks or less) compared with 17.6% of those with symptoms of long duration (16 weeks or more) retained 6/15 (20/50) or better final visual acuity following argon laser photocoagulation treatment.

Adolescent↗