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R Sabatini

Publications and source records attributed to R Sabatini.

At least 37 records · Page 2Linked to original sources

Ovarian dysgerminoma. A clinico-pathologic study.

The authors present the clinical, pathologic and therapeutic report on 5 cases of ovarian dysgerminoma in patients between 15 and 30 years of age, classified as Stage Iai in 3 cases and Stage III in 2 cases. Treatment was surgical in 4 cases; in 1 case the surgery was followed by radiation and chemotherapy. All the patients survive free of disease from 4 to 11 years. One of these neoplasms showed a particular histologic pattern in some way similar to the "spermatocytic seminoma" of the testis. This should be the first time that such a type of ovarian dysgerminoma has been reported in the literature.

Adolescent↗

Direct lymphadenography of the cervix: personal data.

The results obtained by an experimental clinical study about the lymphatic drainage of the uterine cervix by direct intraparenchymal injection of Lipiodol are reported. This study suggests a new approach to the evaluation of cervical carcinoma staging complementary to the peripheral lymphangiography.

Carcinoma↗

In vitro effects of meropenem and imipenem/cilastatin on some functions of human natural effector cells.

Meropenem, a new carbapenem antibiotic, was assessed to evaluate its effects on some functional parameters of human polymorphonuclear (PMN) and natural killer (NK) cells in comparison with imipenem/cilastatin. Both drugs significantly inhibited PMN phagocytosis and chemotaxis at concentrations of 2,000 and 4,000 microg/ml. They affected PMN microbicidal activity, evaluated against Candida albicans, only at 4,000 microg/ml. A study of the effects of both drugs on peripheral NK populations and the human NK line (NK-92) showed that even at 4,000 microg/ml there was no effect on antitumor activity. These data indicate that meropenem can reduce some PMN antimicrobial functions only at very high concentrations like imipenem/cilastatin, whereas no concentration influenced NK activity.

Candida↗