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Biomedical subjects

R Salinas

Publications and source records attributed to R Salinas.

At least 37 records · Page 2Linked to original sources
PubMed1992

Impaired response to recombinant hepatitis B vaccine in HIV-infected persons.

We studied the immunogenicity of the standard schedule of recombinant hepatitis B vaccine (20 micrograms per dose at months 0, 1, and 6) in 21 anti-human immunodeficiency virus (HIV)-positive persons. Relatively low titers of anti-HBs developed in only five subjects (23.8%) 1 month after the third dose; all five had T4 cell counts greater than 700 cells/mm and none of the 11 subjects with a T4 cell count below this value responded. Five of the 16 nonresponders to the vaccine later had acquired immunodeficiency syndrome (AIDS)-related complex (two) and AIDS (three), while none of the responders did. Our results show that anti-HIV-positive persons are poor responders to the recombinant hepatitis B vaccine, and that the absence of a response is an indicator of a more severe immune deficiency and of a poor prognosis. An optimal regimen of hepatitis B vaccination in HIV-infected persons is still to be established.

Follow-Up Studies↗
PubMed1990

Seroprevalence and risk factors for HIV transmission among female prostitutes: a community survey.

To estimate the prevalence of HIV-1, HIV-2 and HTLV-I among female prostitutes, and to identify possible risk factors for HIV transmission in this collective, sera and epidemiological information from 71 prostitutes were obtained. Using the local network of a well-defined area in southern Catalonia, all prostitution bars were identified and their working women interviewed using a previously validated questionnaire. Eight sera were found positive for HIV-1 antibodies. Of those, 7 sera were also positive in the HIV-2 assay, probably as a result of cross-reactivity between the two viruses. All sera were negative for HTLV-I antibodies. In our area, where intravenous drug users (IVDUs) account for the majority of AIDS cases, the use of drugs by the prostitutes or by their steady sexual partners seems to be the most important risk factor for HIV infection in that group.

Adolescent↗
PubMed1990

[Normal development of the lateral ventricle of the fetus--study of improved early detection of fetal hydrocephalus].

The widths of foetal lateral ventricles and hemispheres were measured in 197 normal pregnancies in addition to routine ultrasound foetometry between the 12th and 40th weeks of gestation. The 95% confidence intervals of foetal lateral ventricle hemisphere ratios were calculated by means of regression analysis. The mean value for the occipital horn hemisphere ratio was 0.57 in the 12th week of gestation and 0.21 in the 40th week of gestation. The mean value of frontal horn hemisphere ratio was 0.41 in the 12th week of gestation and 0.18 in the 40th week of gestation. Values exceeding the upper limit of 95% confidence interval are indicative of early development of foetal hydrocephalus and should be followed by further foetal investigations.

Cerebral Ventricles↗
PubMed1989

[Intramyoma intrauterine device].

This article describes a cases of "missing strings" of a Zipper IUD embeded in an intracavitary myoma. Two attempts with classical procedures failed to remove it and the diagnosis was done after a hysteroscopy complicated with uterine perforation. It is very difficult to assure if the myoma grew around the IUD or it was perforated at the time of its insertion. Histological evidences lead to the first option.

Adult↗
PubMed1988

Intrauterine development of posthaemorrhagic hydrocephalus.

Differential diagnosis of intrauterine hydrocephalus includes various types of cerebral malformations. In about 30% of cases the pathogenesis remains unknown. During 1983-1985 we diagnosed intrauterine posthaemorrhagic hydrocephalus (IPHH) in four newborns. In three of the reported cases intraventricular haemorrhage (IVH) could already be proven in the fetus. Due to these observations, IPHH has to be considered with the differential diagnosis of congenital hydrocephalus. Haemorrhagic diathesis and multiple pregnancy are discussed as possible risk factors for this severe fetal complication.

Adult↗
PubMed1984

A simple device to aid impalement of cells using conventional microelectrode drives.

Consistent penetration of cell membranes by micropipettes is facilitated by using electrode accelerators or high velocity step drives. Notwithstanding, much intracellular work is still done with conventional mechanical or hydraulic drives; cell membrane penetration is achieved by means of gentle taps on any convenient part of the set up. A remote control device is described which performs this function and is compact enough to be fixed on either the microelectrode holder or the preparation mounting. It consists of a small magnetized rod freely suspended in a pot-core coil. A current pulse through the coil jolts the rod; the inertial reaction of the coil frame provides the sudden movement required by the micropipette tip to overcome the elastic resistance of the cell membrane.

Animals↗
PubMedDate not supplied

[Effect of budesonide on bone density and metabolism in asthmatic children].

OBJECTIVE: To assess the effect of inhaled budesonide on the mineral density, content and bone metabolism in children with asthma. MATERIAL AND METHODS: From September 1996 to July 1997, a cross-sectional study was conducted in 38 prepubertal children aged 6 to 11 years, selected from the pediatric chest outpatient clinic of the Instituto Autónomo Hospital Universitario de Los Andes, Mérida, Venezuela. Three study groups were assembled: 9 asthmatic children treated with inhaled budesonide (300 micrograms/day) for over 6 months (Group A); 14 asthmatic children not treated with inhaled corticosteroids (Group B); and 15 non-asthmatic children (Group C). All of them underwent testing of bone formation and resorption markers, and measurement of bone mineral density (DMO) and content (CMO). Statistical analysis consisted of central tendency and dispersion measures, analysis of variance, and Fisher and Scheffe tests for comparison of means. RESULTS: In the groups studied (A, B, and C) calcium serum levels were 9.1 +/- 0.3; 9.6 +/- 0.4; 9.3 +/- 0.6 mg/ml, respectively; osteocalcin levels were 14.8 +/- 4.6; 13.0 +/- 2.5; 11.9 +/- 3.4 ng/dl; the type I collagen carboxyterminal telopeptide (ICTP) levels were 19.6 +/- 16.5; 14.2 +/- 15.4; 13.0 +/- 18.3 micrograms/l; the DMO levels were 0.67 +/- 0.06; 0.68 +/- 0.06; 0.69 +/- 0.06 g/cm2; and the CMO levels were 1,158.8 +/- 217.4; 1,106.4 +/- 256.1; 1,176.5 +/- 240.5 g, respectively. No statistically significant differences were observed between the groups. CONCLUSIONS: The administration of 100-400 micrograms/day of inhaled budesonide for a period of six months, did not change the bone mineral density and metabolism of asthmatic children.

Asthma↗
PubMedDate not supplied

Seminar on adult mortality and orphanhood in the past: five Latin American cases.

This report concerns a seminar on adult mortality and orphanhood in the past in Latin America that was held in San Jose, Costa Rica, December 12-14, 1984. The first part describes five historical studies presented at the seminar concerning Mexico, Chile, Peru, Brazil, and Argentina. "The second part of this article is an explanation of the calculation involved in a life table derived from information on the incidence of orphanhood according to the age of newly married couples on their marriage."

Americas↗