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R Sander

Publications and source records attributed to R Sander.

At least 19 recordsLinked to original sources
PubMed1989

The water jet-guided Nd:YAG laser in the treatment of gastroduodenal ulcer with a visible vessel. A randomized controlled and prospective study.

In a randomized, prospective study, 57 patients with a gastroduodenal ulcer and a visible vessel with or without spurting bleeding were treated with a Nd:YAG laser (lambda = 1.064 nm). Twenty-eight of these patients were treated using the conventional non-contact (NC) modality, and 29 were treated with the water jet (WJ) laser. Apart from the technical advantages (minimal smoke development, no damage to adjacent structures) the WJ group had a lower rate of induced spurting bleeds (25% WJ versus 55% NC). The therapeutic failure/mortality rate of 7%/0% respectively for the water-jet group was lower than the 18%/7% for the non-contact group. The initial clinical results of this study suggest that the water-jet Nd:YAG laser system is superior to the non-contact system.

Aged↗
PubMed1989

[Palliative treatment of malignant stenoses of the esophagus and cardia: laser therapy versus laser + high-dose-rate Iridium 192 afterloading therapy. A prospective randomized study].

In order to compare the local efficiency of two different therapy modalities, 37 patients with advanced inoperable tumors of esophagus and cardia were evaluated hitherto in a prospective randomized study. Twenty patients received an exclusive laser treatment, 17 were additionally submitted to three high-dose-rate iridium-192 afterloading irradiations (single dose at the reference point 1 cm radially to the source: 7 Gy). In both groups, 15 patients died whose survival times were not different (125 versus 130 days), however, a beneficial influence was exerted by the afterloading therapy with respect to the duration of the palliative effect (67 versus 28 days) and the hospitalization time (25 versus 48 days).

Adenocarcinoma↗
PubMed1989

Child's play.

Explore the source record for details and available documents.

Aged↗
PubMed1988

Prophylactic sclerotherapy before the first episode of variceal hemorrhage in patients with cirrhosis.

The value of sclerotherapy as prophylaxis against the first episode of variceal hemorrhage has not been established. Therefore, we randomly assigned 133 patients with cirrhosis of the liver (of alcoholic origin in 66 percent), esophageal varices, and no previous intestinal bleeding to either prophylactic sclerotherapy (n = 68) or no prophylaxis (n = 65). The groups were comparable in hepatic function, endoscopic findings, and the pathogenesis of cirrhosis. All patients who subsequently had a first episode of variceal hemorrhage received sclerotherapy whenever possible. During a median follow-up of 22 months, variceal hemorrhage occurred in 28 percent of the patients receiving sclerotherapy and 37 percent of the controls (P = 0.3). Thirty-five percent of the sclerotherapy group and 46 percent of the control group died. The survival curves (Kaplan-Meier) of both groups were similar (P = 0.2). However, among patients with alcoholic and moderately decompensated cirrhosis (Child-Pugh group B), survival was significantly higher in those receiving sclerotherapy, although the risk of bleeding was only marginally reduced by this procedure. We conclude that prophylactic sclerotherapy does not significantly reduce the risk of bleeding from esophageal varices, but that a subgroup of patients with esophageal varices and moderately decompensated alcoholic cirrhosis may benefit from prophylactic sclerotherapy because of factors not solely attributable to prevention of an initial episode of variceal bleeding.

Adolescent↗
PubMed1987

Palliation of obstructive oesophageal and cardial carcinomas with laser and endoluminal iridium radiation.

The combination of laser with endoluminal 192-iridium radiation for the palliation of malignancies of the oesophagus and the cardia has been introduced to overcome the short-lived effect of laser treatment alone. Concluding from early experience, this method seems to prolong the effect of laser treatment alone, with a low risk of complications. However the initial optimistic results, claiming a permanent relief of dysphagia in 80% of the patients, cannot be reproduced under prospective conditions. The combination of laser and 192-iridium radiation with other palliative methods, such as external radiation and/or chemotherapy is feasible and remains to be studied in a comparative way.

Brachytherapy↗
PubMed1987

Laser and endoluminal 192-iridium radiation.

The combination of laser and endoluminal 192-iridium irradiation for the palliation of malignancies of the esophagus and the cardia was introduced to overcome the short-term effect of laser treatment alone. On the basis of early experience, this method would seem to prolong the effect of laser treatment alone, and is associated with a low risk of complications. However, the initial optimistic results, claiming permanent relief of dysphagia in 80% of the patients, cannot be reproduced under prospective conditions. The combination of laser and 192-iridium irradiation with other palliative methods, such as external radiation treatment and/or chemotherapy is feasible, and remains to be studied in a comparative way.

Brachytherapy↗
PubMed1986

Endoscopic papillotomy with Nd:YAG laser: an alternative to electrocautery.

With the presentation of two cases of successfully performed endoscopic papillotomies, a new indication for Nd YAG laser treatment in gastroenterology is introduced. To the extent it thus far has been used, photocoagulation is a complementary alternative method if the usual papillotomy cannot be placed in the right cutting position.

Aged↗
PubMed1986

Treatment of benign gastrointestinal tumors with the neodymium:YAG laser.

Between November, 1978 and July, 1985 36 recurrent broad-based villous adenomas in the gastrointestinal tract were treated with the Nd:YAG laser. Treatment was successful in 29 patients, who showed no recurrence within a period of six months or more. The average follow-up time was 16 months. Seven patients are still being treated. No serious complications occurred.

Adenoma↗
PubMed1986

Diethylstilbestrol-associated vaginal adenosis followed by clear cell adenocarcinoma.

A young woman was examined because of a history of in utero exposure to diethylstilbestrol and was identified as having vaginal adenosis. Fourteen months later, on routine follow-up, a small vaginal clear cell adenocarcinoma was recognized. She refused any therapy other than wide local excision. She was seen intermittently for several years with no recurrence. Five and one-half years after initial diagnosis she was found to have multiple sites of clear cell adenocarcinoma in the upper third of the lateral and anterior vaginal walls. Cases of vaginal adenosis followed later by the development of clear cell adenocarcinoma (metachronous cases) are distinctly unusual. The authors have collected the other recorded cases in the literature or in the Registry for Research on Hormonal Transplacental Carcinogenesis and have attempted to compare these cases with the larger group of patients who present with clear cell adenocarcinoma and have associated vaginal adenosis (synchronous cases). The authors have found few differences between the two groups. Most of the differences can be accounted for by the close follow-up of patients with known vaginal adenosis. However, it has been noted that the location of the clear cell adenocarcinoma is apparently different in the two groups. The reasons for this apparent difference are briefly discussed.

Adenocarcinoma↗
PubMed1985

Endoscopic papillotomy with the Nd YAG laser.

A case of successful endoscopic papillotomy with the Nd YAG laser in a patient with choledocholithiasis after partial stomach resection is reported. This new technique is a complementary alternative for papillotomy when high-frequency diathermy is not suitable.

Aged↗
PubMed1985

A comparison of reference method values for sodium, potassium and chloride with method-dependent assigned values.

The concentrations of sodium, potassium, and chloride in various control sera were determined by reference methods. The reference method values were compared with the corresponding method-dependent assigned values. Sodium: Measurements by flame photometry and ion selective electrodes differed on the whole by less than 1% from the reference method value; determinations by photometry differed, however, by -4.7%. Potassium: The mean bias was -1.2% with flame photometry and -0.4% with ion selective electrodes, whereas nephelometric procedures differed by -1.9 or -4.8%. Chloride: Satisfactory agreement was obtained with values given for ion selective electrodes (-0.3%), for some coulometric procedures (-0.7 and 0.4%), and photometric determinations using mercury rhodanide (-0.5 and +0.7%). Values for mercurimetric titration and for photometric determinations using mercury 2,4,6-tri-(2-pyridyl)-s-triazine differed by + 2.5 and + 1.8%. Proposals concerning the allowable deviation from reference method values are discussed.

Chlorides↗
PubMed1985

[Endoscopic laser therapy].

The Nd-YAG-laser is being used since ten years in gastroenterological endoscopy with good success. It can be used for treatment of bleeding lesions or lesions which potentially could bleed, for treatment of benign and malignant tumors, treatment of non-neoplastic stenoses and pathological changes in the region of the papilla. Own results with this treatment in 1033 patients are reported, demonstrating high efficacy of this method by improving quality of life and decreasing the number of surgical interventions necessary and also decreasing hospital lethality.

Ampulla of Vater↗