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Biomedical subjects

R Sanderson

Publications and source records attributed to R Sanderson.

25 records · Page 2Linked to original sources
PubMed1975

The holding power of orthopedic screws in vivo.

Great difficulty is encountered in choosing screws for internal fixation, for screws differ in material, geometry, dimension, and in insertion technique. Recently claims have been made that self-tapping screws cause necrosis of bone and result in fibrous tissue formation, with loss of holding power. This investigation was undertaken to study the healing of bone about screws inserted for a period of 3 months. Self tapping and non-self tapping screws were employed. The Vitallium screws not only differed in dimension, but also in configuration of the thread, with the smaller of the self-tapping screws exhibiting a "V" thread in distinction to the buttress thread of the larger screw. The histologic data were correlated with the holding power of the screws as obtained by means of a push out test, performed with the aid of an Instrom testing machine. The largest screw tested, the 4.5 mm non-self tapping stainless steel AO screw (Type 1), provided the greatest safety factor to push out loading over the period tested in the unloaded system. The self tapping and non-self tapping screws of similar material and size were found to maintain comparable holding power at all intervals tested in vivo in the unloaded system. No histological differentiation could be made with regard to both death or tissue reaction around the implant, between the stainless steel or cobalt chromium alloy materials, nor between the self tapping and non-self tapping insertion methods.

Animals↗
PubMed1975

Methymethacrylate cement: its curing temperature and effect on articular cartilage.

The increasing use of methylmethacrylate in orthopedic surgery makes it desirable to determine whether the curing temperature of methylmethacrylate is high enough to cause bone necrosis and whether methylmethacrylate damages articular cartilage. Studies in dogs showed that methylmethacrylate plut temperatures ranged from 95 to 107degrees C and that temperatures at the cement-bone interface ranged from 50 to 95degrees. Curing temperatures therefore are high enough to cause necrosis of bone. Other studies revealed no harmful action of methylmethacrylate on articular cartilage. Fractures stabilized with methylmethacrylate can therefore be expected to heal provided the normal criteria of fracture management are fulfilled.

Animals↗
PubMed1969

Bovine para-influenza 3 vaccine studies.

A bovine para-influenza 3 modified live virus vaccine was studied in colostrum-deprived calves. A single dose of vaccine induced antibody responses and afforded protection against experimental challenge. This was evidenced by reduced clinical disease and virus excretion as compared to unvaccinated control calves. The vaccine virus did not spread from vaccinated calves to contact controls.

Animals↗
PubMedDate not supplied

Transverse traction in the treatment of scoliosis. A preliminary report.

Nineteen scoliotic patients were treated with the standard Harrington distraction rod supplemented with transverse traction. The latter consists of a compressive device (either Harrington';s or Cotrel's) applied to the convex side of the curve to correct disc space wedging and then drawn toward the distraction rod with a simple traction apparatus. Intraoperative roentgenograms were taken with the Harrington distraction rod alone after maximal distraction was applied. This was followed by postoperative roentgenograms with the transverse traction added. The 50.3% correction by distraction rod alone is increased to 66% with the addition of transverse traction. Detailed analysis of each curve, segment by segment, showed that the correction was augmented, not only in the center of the curve, where the compression corrected disc space wedging, but in the ends of the curve as well. This series uses each patient as his or her own control in demonstrating increased correction added by transverse traction.

Adolescent↗