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Biomedical subjects

R Schiffter

Publications and source records attributed to R Schiffter.

At least 19 recordsLinked to original sources

[The suffering of Heinrich Heine].

The analysis of clinical neurological symptoms on the basis of available letters and other documents confirms beyond a doubt the long standing diagnosis of neurosyphilis in the form of chronic meningitis with cranial polyneuritis and wide spread polyradiculitis, formerly called Lues cerebro-spinalis. The symptoms which recurred over 25 years include multiple severe paralysis of cranial nerves, dramatic radicular neuralgias and radicular paralysis in addition to a partial transverse lesion of the spinal cord and terminal coughing and regurgation fits in the absence of symptoms in the cerebrum and brain stem, these symptoms hardly permit different diagnosis. Tuberculosis, lead poisoning, multiple sclerosis or even a myatrophic lateral sclerosis do not explain his neurological symptoms or the cause of his death.

Famous Persons↗

Hypersexuality--a complication of dopaminergic therapy in Parkinson's disease.

Hypersexuality induced by dopaminergic drug treatment in parkinsonian patients is a rarely reported side-effect. A case history is presented where it occurred together with hyperkinesias while the patient was treated with L-dopa and bromocriptine. An addictive misuse of these drugs complicate the guidance of this patient. Approximately three years after the beginning of hypersexuality he developed several paranoid-hallucinatory psychoses which subsided each time upon dose reduction.

Benserazide↗

The telodiencephalic ischemic syndrome.

A new cerebral syndrome is described which occurs rather frequently with ischemia affecting the common pathway of the internal carotid and middle cerebral arteries. The syndrome consists of contralateral brachiofacial hemiparesis, possibly with hemianopia and/or aphasia, and ipsilateral thermoregulatory hemihypohidrosis with an ipsilateral central Horner syndrome. It is caused by an ischemic lesion of the crossed pathways descending from the cerebrum and the uncrossed hypothalamo-spinal sympathetic pathways descending through the subthalamic region. It is suggested to name the syndrome "telodiencephalic ischemic syndrome".

Body Temperature Regulation↗

[Complete loss of brainstem-functions following epidural anaesthesia (author's transl)].

A 77 year old male patient developed complete loss of brainstem-functions following epidural anaesthesia for prostate electroresection. On the basis of anatomical and pathophysiological considerations an attempt is made to explain the development of this event. The most important factor seems to be that the local anaesthetic agent can diffuse into the subarachnoid space via the arachnoid villi, which can protrude into the epidural space. Once in the subarachnoid space the anaesthetic can ascend. By this mechanism a complete loss of brainstem functions may evolve. Survival without residual deficit is possible if immediate intensive care with control of the vital functions is instituted.

Aged↗

[Neurological findings (especially "developmental reflexes") in residents of homes for the aged (author's transl)].

86 residents of several homes for the aged in Berlin, aged 75 to 96 years (mean age 86.3 years), were examined neurologically. Many showed the following aberrant neurological signs: Pallaesthesia and dermolexia were extinct in the lower extremities; the ankle jerks could not be elicited; the palmomental, orbicularis oris reflex, grasping and the snout reflexes were positive; there was a hypokinetic-hypertonic motor syndrome. The statistical analyses and the follow-up dynamics of our findings argue for such age-dependent changes of the CNS as the basis for the grasping and snout reflexes and for the involuntary movements of the elderly.

Aged↗