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Biomedical subjects

R Seiler

Publications and source records attributed to R Seiler.

At least 37 records · Page 2Linked to original sources
PubMed1990

[Plague and creative art. On the influential effect on art of the 14th century by black death].

The present paper tries to shed light on the influence of the plague upon art. It considers above all the period after the "Black Death", i.e. the second half of the 14th century. Some changes of art are quantitative: its production is lessened by the effects of the plague--e.g. by the death of an artist--or increased by religious donations. The influence on style is similarly contradictory. Retardation as well as acceleration of the stylistic development can be observed. A third point consists in the changes in iconography of "Post-Plague-Art", showing a different interpretation of existing themes or introducing new ones. The varied conditions of production and reception of the different artistic genres makes the examination of the interaction between plague and art extremely complex.

Europe↗
PubMed1987

[Ventriculo-peritoneal cerebrospinal fluid drainage in the treatment of hydrocephalus].

From January 1980 to December 1984 67 patients with hydrocephalus were treated with v-p shunts at the University Hospital, Berne. 61.2% had obstructive hydrocephalus and 38.3% communicating hydrocephalus. They were followed up for 2 to 6 years. Apart from clinical examination, computerized tomography was the single most important procedure for diagnostic purposes as well as for follow-up. This was not true in the case of communicating hydrocephali treated with an antisiphon device. 8 patients had serious early complications, with two fatal cases. There were not late complications. 90% of the clinical symptoms were improved or cured. V-p shunt is a technically simple and clinically effective operation, but in view of a complication rate of 12% the indication requires critical assessment.

Adolescent↗
PubMed1986

[Transcranial Doppler sonography. A new method for the diagnosis of cerebrovascular diseases].

Transcranial Doppler sonography, a new method for the evaluation of cerebrovascular disease, is presented. After outlining the technical basis, investigation technique and normal values, the authors describe the utility of the method for the evaluation of stenosis and occlusions of the extracranial and intracranial arteries, spasms after aneurysmatic subarachnoid hemorrhage, arteriovenous malformations, and patients with arrested cerebral circulation due to high intracranial pressure. The value of Doppler methods for the evaluation of cerebrovascular diseases is discussed.

Cerebral Angiography↗
PubMed1986

Transcranial Doppler sonography. An alternative to angiography in the evaluation of vasospasm after subarachnoid hemorrhage.

With transcranial Doppler sonography (TCD) the blood flow velocity (FV) in the basal cerebral arteries can be measured non-invasively. Vasospasm produces an increase of the FV in the narrowed arterial segment which can be evaluated by TCD. A clear correlation between the diameter of the artery and the increase in FV could be demonstrated in the middle cerebral artery. Vasospasm can be detected by TCD non-invasively and angiography can be avoided during the critical phase. The time course of vasospasm can be followed by TCD instead of repeated angiographies, enabling an optimal timing of aneurysm surgery.

Adult↗
PubMed1985

[Respiratory functional hypoxia in ruminants under general anesthesia].

General anesthesia causes a marked hypoxia in ruminants. We compared this phenomenon with anaesthesia related changes in the dog. Under alfentanil/etomidat anaesthesia some variables of the pulmonary circulation (TPR, PAP, PCWP) as well as arterial and venous blood gases and saturation (HbO2, pO2, ph) in dogs, sheep and calves were measured and calculated. The calculated pulmonary shunt fraction was compared between the three species. In ruminants there was an increase of total pulmonary resistance being associated with elevated PAP and decreased PCWP. The pulmonary shunt fraction was increased significantly and markedly during the surgical tolerance period, too. These parameters were not significantly changed in the dog. Ruminants seem to take an exceptional position concerning the anaesthesia related alterations of the pulmonary ventilation/perfusion system.

Adjuvants, Anesthesia↗
PubMed1984

The presence of steroids in larval and mature brook lampreys (Lampetra planeri Bloch).

The presence of steroids was investigated by radioimmunoassay - mass spectrometry in serum and homogenates of gonads and presumed adrenocortical (pro- and opisthonephric) tissue of larval and mature brook lampreys (Lampetra planeri Bloch) of both sexes. Pregnenolone was detected in all tissue samples studied whereas androstenedione could be identified only in presumed adrenocortical tissue from male and female mature animals as well as in testis. Testosterone was present in testis of adult lampreys and in sera of larval and adult animals.

Androstenedione↗
PubMed1983

Spectrophotometric analyses of hydroxysteroid dehydrogenase activity in presumed steroid-producing tissues of the brook lamprey (Lampetra planeri bloch) in different developmental stages.

Hydroxysteroid dehydrogenase (HSD) activity was determined spectrophotometrically on homogenates of the pronephros, the opisthonephros, and the gonads of metamorphosing, immature, and mature adult male and female brook lampreys (Lampetra planeri Bloch), employing pregnenolone, dehydroepiandrosterone, androsterone, epiandrosterone, and 3 beta,17 beta-dihydroxy-5 alpha-androstane as substrates and NAD or NADP as coenzymes in October, December, February, and April. With NADP a higher HSD-dependent HSD activity was detected in presumed adrenocortical tissue (PAT) homogenates with pregnenolone and 3 beta,17 beta-dihydroxy-5 alpha-androstane and in gonad homogenates only with 3 beta,17 beta-dihydroxy-5 alpha-androstane. With 3 beta,17 beta-dihydroxy-5 alpha-androstane as substrate the highest enzyme activities were measured in PAT and gonad homogenates from animals of all investigated life stages. A varying intensity of HSD activity in the examined tissue homogenates probably dependent on stages of the individual development was observed.

3-Hydroxysteroid Dehydrogenases↗
PubMed1983

Subarachnoid hemorrhage with normal cerebral panangiography.

Forty-two nonhypertensive patients with a proven subarachnoid hemorrhage but normal cerebral panangiography were in vestigated. The follow-up period was 1 to 5 years, with a mean of 39.1 months. Treatment consisted of 2 weeks of bedrest and sedation, followed by progressive mobilization on the 3rd week. Thirteen patients (Group A) were treated with tranexamic acid, whereas 29 patients (Group B) received no antifibrinolytic therapy. Five patients Of Group A died of ischemia caused by cerebral vasospasm. No patient of Group B died, and there was no early rebleeding in either group. Therefore, antifibrinolytic therapy is not indicated in these patients. Only 1 of 42 patients (2.4%) experienced late rebleeding, and he again had normal cerebral panangiography. Reangiography several weeks or months after the first hemorrhage seems not to be indicated. The overall prognosis of the surviving patients was good; almost all were able to return to their previous occupations within 6 months after the hemorrhage.

Adult↗
PubMed1981

Histochemical and spectrophotometric demonstration of hydroxysteroid dehydrogenase activity in the presumed steroid producing cells of the brook lamprey (Lampetra planeri Bloch) during metamorphosis.

Pronephric, opisthonephric, ovarian, and testicular tissue rich in presumed steroid producing cells taken from the brook lamprey during metamorphosis was investigated by histochemical and spectrophotometric methods. Histochemical results seemed to provide evidence for hydroxysteroid dehydrogenase activity using pregnenolone as substrate. Spectrophotometric evidence for hydroxysteroid dehydrogenase activity was obtained from presumed adrenocortical tissue, ovarian and testicular homogenates using pregnenolone, dehydroepiandrosterone, androsterone, and 3 beta, 17 beta-dihydroxy-5 alpha-androstane as substrates.

Animals↗
PubMed1980

[Ontogenesis of facial muscles in primates].

1. The development of facial muscles is studied in embryos of Tupaia belangeri, Tupaia javanica, Nycticebus coucang, Galago dimidovii, Tarsius bancanus, Callithrix jacchus, Colobus badius, Colobus verus, Nasalis larvatus, and Homo sapiens. 2. The facial muscles derive from a superficial blastema (anlage of platysma myoides) and another blastema laying beneath the first one (anlage of sphincter colli muscle). Both blastemas grow out from mesenchymal cells of the head after the anlagen of all other muscles are visible. 3. The myoblasts are arranged along the margines of the blastemas in a way that outline the run of the muscles. 4. Superficial muscle derives from the anlage of platysma, the profound muscles of the mouth and some of the rostral margine of the auricle derive from the anlage of sphincter colli muscle. 5. In species without sphincter colli muscle the myoblasts for muscles considered as derivates of sphincter colli (those muscles are identificable as derivates of sphincter colli in species which have it) grow out from mesenchymal cell directly. 6. The ontogenetic results show the principle of the way in which the facial muscles have evolved during phylogeny as described in comparative anatomy. 7. Muscles, which were present in an early state of phylogeny f. e. like sphincter colli muscle in the ancestors of Katarrhina, hav no anlage which later become reduced. 8. The facial muscles have a complete differentiation in an early state of prenatal development and the operate well until to the time of birth.

Animals↗
PubMed1979

[Criteria of the homology and phylogeny of facial muscles in primates including man. I. Prosimia and Platyrrhina].

The facial muscles of primates are derivates of sphincter colli profundus muscle and platysma myoides. A third superficial muscle layer which is present in primitive mammals is found as a rest in Tupaiiformes. The facial muscles of some Lemuriformes must be considered as a model from which originate the facial musculature of other primates. The new formation of muscles takes place at the margine of the original muscle layers; marginal muscle fibers assume another run and get individualized. So it can be seen in facial muscles of prosimians and platyrrhine monkeys that the profound muscles of mouth and nose and some of the rostral margine of the auricle have orginated from sphincter colli muscle, all others from platysma myoides. Primitive and modified muscle forms and intermediate muscle forms can be observed among prosimians as well as among platyrrhine monkeys and by this it is possible to see the homology of the facial muscles.

Animals↗
PubMed1978

HLA and glioma.

HLA typing of 80 glioma patients was determined and the antigen frequencies were compared with 176 normal controls. Increased phenotypic frequencies of Bw35 and DRw1 were observed, but when P values were corrected by the number of antigens tested (35), the results were no longer significant.

Adolescent↗
PubMed1978

Primary osteosarcoma of the sternum of a dog.

Primary osteosarcoma of the fifth sternebra is reported in a 6-year-old male Great Dane. Presenting signs were suggestive of myocarditis and pulmonary congestion. Electrocardiography revealed R waves of low and variable amplitude and the plasma alpha-hydroxibutyrate dehydrogenase level was elevated. Radiography revealed neoplasia of the fifth sternebra with extensive bilaterial pulmonary metastases. Histologically the neoplasm showed typical osteosarcoma with plentiful osteoid production.

Animals↗