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Biomedical subjects

R Sfar

Publications and source records attributed to R Sfar.

17 recordsLinked to original sources

[Endometrioid adenocarcinoma of the uterine cervix associated with mucinous ovarian cystadenocarcinoma].

The authors report the case of a 40-year-old woman, who was operated for an ovarian mucinous cystadenocarcinoma. The pathologic findings of the hysterectomy specimen with bilateral salpingoophorectomy showed an ovarian mucinous cystadenocarcinoma associated with an endometrioid adenocarcinoma of the uterine cervix. The mucinous cystadenocarcinoma represents the third most common type of ovarian carcinoma. In the literature, this tumor had been found in association with endocervical adenocarcinoma or with minimal deviation adenocarcinoma (adenoma malignum) of the uterine cervix. However, its association with an endometrioid adenocarcinoma, to our knowledge, has not been reported.

Adult↗

[Subperiosteal hematoma in delivery].

Spontaneous subperiosteal hematoma of the orbit is uncommon and only five cases have been reported in literature. The aim is to report a new case of this exceptional complication of labour and delivery. A 28-year-old woman developed immediately after delivery exophthalmia, chemosis and diplopia. CT scan showed a subperiosteal hematoma of the orbit. Spontaneous evolution was good. For her second pregnancy, caesarean section was decided because of the risk of recurrence. Since no etiology is found, venous hyperpression occurring during labor could be the lone origin.

Adult↗

[Papillary thyroid microcarcinoma presenting as cervical lymph node metastasis. Interest of tetrofosmin scintigraphy and lymph node thyroglobulin measurement].

PURPOSE OF THE STUDY: Thyroid microcarcinoma presenting as cervical lymph node metastasis is common and it is associated in most cases with the papillary variety. Diagnosis of lymph node metastases from a thyroid microcarcinoma is not always easy, because a thyroid nodule may not be palpable. MATERIAL AND METHOD: In this work, the authors report two cases of papillary microcarcinoma presenting as cervical lymph adenopathy. RESULTS: The diagnosis was made preoperatively by Tetrofosmin scintigraphy and thyroglobulin measurement in the lymph node. CONCLUSION: Tetrofosmine scintigraphy is a performing exam but with a poor specificity. Lymph node thyroglobulin is a simple exam which is very sensitive and specific.

Adult↗

[Bronchopulmonary dysplasia and corticosteroid therapy].

Inflammation plays a major role in the pathogenesis of bronchopulmonary dysplasia of preterm infants. Having a strong anti-inflammatory effect, corticosteroids have been proposed in the management of this disease. Antenatal steroids protect the newborn against its development. Postnatal systemic administration of steroids reduces the duration of mechanical ventilation and oxygen therapy, but is associated with short term and long term adverse effects. Early administration of dexamethasone (before 7 days of life) reduces the incidence and the severity of chronic lung disease at 28 days of life and 36 weeks of post-conceptional age. Inhaled steroids are associated with less adverse effects than dexamethasone administration, but they are also less effective.

Administration, Topical↗

[Surveillance system of maternal mortality in the Tunis region].

In the framework of a national strategy of reduction of the maternal mortality rate. Tunisia has set up a follow up system of maternal deaths occurring in public facilities to analyse their causes, the levels of deficiency and to propose solutions for preventing them. This note aims at describing the system, its results, its efficiency and its limitations in the Tunis region for the years 1999 and 2000. The results show a maternal mortality rate estimated at 80 for 100,000 births in public facilities of the region: the main causes being haemorrhage (42.1%) followed by infection (13.2%). The proportion of avoidable deaths is 87%:74% possibly avoidable and 13% certainly avoidable, factors related to women behaviour have also contributed to 45% of cases. The system flows are however intricated, and related to organization: an underestimation of risk by the patient (33%), an inadequate watch during the postpartum period (25%), a late hospitalisation (22%) and not enough reanimation equipment. Nevertheless, this control system has achieved part of its objective by starting up a quality approach to obstetrical cares and by warning health professionals such as obstetricians, anaesthetists, blood banks in charge, hospital managers and other medical teams. The limitations of the system are tied to the follow up of the real implementation of recommendations stated in reports at a local as well as central levels.

Bias↗

[Placenta accreta. Ten cases].

A retrospective analysis of 10 cases of placenta accreta observed from 1983 to 1993, all confirmed histologically, were reviewed at the Gynaecology-Obstetric B ward of the Charles Nicolle Hospital in Tunis. The incidence of this placental anomaly is 1 for 7,139 births. The condition is usually discovered due to excessive bleeding at delivery. In 10 cases, hysterectomy was required for haemostasis. There were 3 maternal deaths. The insertion of the placenta on a uterin scar is highly suggestive of placenta accreta. The increase in the incidence of this pathology over the last years is probably related to the increase in the number of cesarean sections. When observed, hysterectomy provides the best chances of survival.

Adult↗

[Robert's uterus with menstrual retention in the blind cavity].

Robert's uterus or asymmetric septate uterus is a rare malformation. It presents with two cavities, one of which is blind. The authors report an original case: the blind cavity, on the right side of the septum, contained retained secretions. The embryologic and physiopathologic mechanism of this anomaly still are to be discussed.

Adult↗

[Association of Takayasu arteritis, Crohn disease and pregnancy].

The authors report a case of a pregnant woman with Takayasu's arteritis and Crohn's disease. The course of pregnancy was uneventful. It is suggested that these two inflammatory diseases may be immunologically related. A brief review of the literature confirm that fetal and maternal prognosis are generally excellent.

Adult↗

[Obstetrical prognosis of gestational pemphigoid. Study of a series of 13 cases and review of the literature].

Pemphigoid gestationis (PG) Herpes Gestationis (HG) is an auto-immune bullous dermatosis which usually occurs in pregnancy. We have studied the maternal and fetal prognosis of this pathological condition. Thirteen cases were reported at the same time by the departments of dermatology and obstetrics of the Charles-Nicolle Hospital between 1980 and 1990. Two women were not followed up. In the remaining eleven there was one intrauterine fetal death and one intrauterine fetal growth retardation (IUGR). One case was delivered prematurely because of obstetric indications. Four infants were delivered by Caesarean section on purely obstetrical indications. The other cases were delivered normally. There were no dermatological lesions or other malformations in the infants. Immediately after delivery ten women showed exacerbation of the skin lesions and most of these were treated by general corticotherapy. Our results were compared with those found in the literature. The prognosis differs according to different authors but in order to avoid any risks the condition must be followed carefully by obstetricians and dermatologists and laboratories working together.

Adult↗

[Factors influencing the length of hospitalization after a cesarean. Statistical study on 645 cesareans].

The duration of hospitalization after a caesarean section is still a current topic, but it remains very scarcely documented. We have undertaken a research through a statistical analysis of the factors influencing the duration of hospitalization after a caesarean. The results are collated with the literature. Our retrospective study concerned 645 cesareans performed at the gyn. obst. department at Charles-Nicolle Hospital between June 1989 and May 1990. The average length of hospitalization after a caesarean was of 4.7 (+/- 2.2 days). The age of the patient, the type of incision, the state of the child or the antibiotherapy have no influence on the length of hospitalization after a caesarean. However, the latter increases significantly with the following factors: un married mothers, multiparity, medical maternal previous history, and per and post operative complications.

Adolescent↗

[Compared course of clinical, biologic, echographic and speedometric parameters in retroplancetal hematoma].

The authors have studied 27 cases of Abruptio Placentae (A.P.) (for an observation time of 15 months). These 27 patients where divided into 3 groups: 6 patients without pregnancy follow-up, 5 with a regular follow-up and 16 with an intensive pregnancy follow-up. In this last group following parameters were studied: blood pressure, proteinuria, uricemia, hematocrit, platelet count, FDP, plasma volume, Fetal (umbilical artery) and Maternal (uterine artery velocities with doppler reclude Fetal heart Rate. The total number of intra uterine death and post natal death remained very high: 15 over 27 cases. However this rate was lower in the intensive group, where 10 fetuses with were delivered safely. Studying the evolution of clinical, biological and ultrasonic parameters during the last month before the AP we tried to establish curves of their mean value (every week for the last 4 weeks and every day for the last week). Almost all parameters showed a late significant variation (in the last week). Two of them were modified in the last two days: (FDP and Fetal heart rate acceleration). Two of them were "positive" (in 60 p. 100 of cases) 3 of 4 weeks before the AP: Maternal Plasma volume decrease, Presence of a Notch on the uterine artery doppler curve. In conclusion fetal or neonatal death after AB remains high and even with an intensive follow-up 30 p. 100 of the cases cannot be predicted.

Female↗

[Value of early oral feeding after a cesarean section].

In order to evaluate the advantages and possible disadvantages of early oral realimentation following cesarean section, the authors undertook a randomized prospective study involving 100 patients divided into 2 groups: A, in which oral feeding remained forbidden until the spontaneous restoration of intestinal function; and B, in which oral feeding was restarted as early as 6 hours postoperatively. The results of the study indicate the usefulness of early realimentation after cesarean section which, in particular, enabled a 4 hour decrease in the time before which flatus was passed and a 5-fold decrease in gastrointestinal problems.

Adolescent↗