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Biomedical subjects

R Soderstrom

Publications and source records attributed to R Soderstrom.

6 recordsLinked to original sources

Vaginal douching as a potential risk factor for tubal ectopic pregnancy.

The incidence of ectopic pregnancy in the United States has more than doubled in the past decade. Because a previous study has suggested that the practice of vaginal douching may increase the risk of pelvic inflammatory disease, a condition known to predispose to ectopic pregnancy, and because the sale of commercial douching products in the United States has more than tripled since 1974, we investigated this practice as a possible risk factor. We interviewed 155 women who had a tubal ectopic pregnancy treated at five Seattle hospitals between 1975 and 1979 as to their reproductive, contraceptive, and medical histories, demographic characteristics, and personal hygiene practices. During the same period, 456 women who were delivered of a baby in King County were identified from Vital Records and interviewed as controls. A higher proportion of cases than controls reported ever having douched in the past. Cases also douched more frequently than controls. After simultaneous adjusting for confounding factors in our data by means of a multiple logistic regression technique, the risk of tubal ectopic pregnancy for women who douched at least weekly was twice that of women who never douched (95% confidence interval = 1.03 to 4.00). The risk for women who used commercial douches on a weekly basis was 4.4 (95% confidence interval = 1.6 to 12.7) the risk for women who never douched.

Adolescent↗

Ectopic pregnancy in relation to previous induced abortion.

Women who were hospitalized for ectopic pregnancy in five hospitals in King County, Washington, were interviewed concerning history of induced abortion. For comparison, women who delivered a live-born child during this same time period were also interviewed. Relative to women who had never undergone an abortion, the risk in those who had was increased to a modest degree, but this increase could well have been the result of chance (relative risk, 1.4; 95% confidence interval, 0.7 to 2.6). For women who had two or more abortions, the relative risk was 1.8 (95% confidence interval, 0.5 to 7.1). Our results suggest that legal abortion as performed during the past decade in the United States does not carry a large excess risk for future ectopic pregnancy, but larger studies will be needed in order to determine more precisely the magnitude of any excess that does exist.

Abortion, Induced↗

Tubal infertility in relation to prior induced abortion.

One hundred twenty-seven women who had been given diagnoses of tubal infertility between 1979 and 1981 in King County, Washington, yet previously had been pregnant, were interviewed to determine their prior history of legally induced abortion. Their responses were compared with those of 395 women who conceived a child at the same time the infertile women began their unsuccessful attempt to become pregnant. In making the comparison, we adjusted for the effects of variables that in this population were related both to having an induced abortion and to the occurrence of infertility, i.e., age, number of prior pregnancies, number of sexual partners, cigarette smoking habits, Dalkon Shield (A. H. Robins Company, Richmond, VA) use, and whether the woman worked outside the home. The risk of tubal infertility in women who had had an induced abortion was not increased above that of other women (relative risk, 1.15; 95% confidence interval, 0.70 to 1.89). For women with two or more abortions, the relative risk was 1.29 (95% confidence interval, 0.39 to 4.20). When only the most recent pregnancy was considered, the relative risk was 1.19 (95% confidence interval, 0.72 to 1.97). Our results suggest that legal abortion, as performed during the past decade in the United States, does not carry an excess risk for future tubal infertility.

Abortion, Induced↗

Salpingitis: a frequent response to intrauterine contraception.

Nonbacterial, chronic salpingitis was found in less than 1% of non-IUD users undergoing elective tubal sterilization, Nonbacterial, chronic salpingitis was found in 47% of IUD users undergoing elective sterilization. Speculation about the influence of this finding on inflammatory morbidity is presented.

Adult↗