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R Somma

Publications and source records attributed to R Somma.

5 recordsLinked to original sources
PubMed1989

Organization of human class I homeobox genes.

We report the genomic organization of 20 human class I homeoboxes and the predicted primary sequence of the encoded homeodomains. These homeoboxes are clustered in four complex HOX loci on chromosomes 2, 7, 12, and 17. The homeoboxes of one HOX locus can be aligned to the homeoboxes of the other HOX loci so that corresponding homeodomains in all loci can share the maximal peptide sequence identity. This correspondence of individual homeoboxes in different chromosomal loci suggests the hypothesis of large-scale duplications of a single complex locus. The existence of an ancestral complex locus might have predated the divergence of vertebrates and invertebrates.

Amino Acid Sequence↗
PubMed1989

[Seroprevalence of antibodies against Trypanosoma cruzi in 13 departments of Uruguay].

In 1985 a study was undertaken of the prevalence of Trypanosoma cruzi antibodies in 13 departments of Uruguay where transmission of the parasite by the vector Triatoma infestans persists. A total of 5,924 serum samples were selected using a probabilistic method--3,840 from individuals over the age of 12 (sample I) and 2,084 from subjects who were 12 years old (sample II). The population was classified according to place of residence (capital city, non-capital city, suburban area, and rural area). The percentage of positive sera detected by indirect immunofluorescence in the different departments ranged from 1 to 11%, and overall seroprevalence for the area was 3.4%. Based on the results obtained, it was possible to distinguish three areas: A, with seroprevalence from 6 to 11%; B, 2 to 3.2%, and C, 1 to 1.4%. In sample II from the Departments of Paysandú, Soriano, Flores, Florida, and Durazno, no cases of Chagas' disease were detected, which suggests that there is no active transmission of T. cruzi in this age group in the area studied. The number of persons estimated to have the disease was 36,952, or 1.3% of the total population of Uruguay and 4% of the population in the area surveyed. These seroprevalence figures are similar to those recorded in the province of Entre Ríos, Argentina, and in the neighboring municipalities of Rio Grande do Sul, Brazil.

Adolescent↗
PubMed1988

Organization of human homeobox genes.

The chromosomal localization of 17 human homeoboxes and the predicted primary sequence of the encoded homeodomains is reported. These homeoboxes are clustered in four complex HOX loci on chromosomes 2, 7, 12 and 17. Although the identification of human homeoboxes has not been completed, existing data permit preliminary conclusions on the origin and evolution of these complex loci to be drawn. The homeo-domains of one HOX locus can be unambiguously aligned to the homeodomains of the other HOX loci, so that corresponding homeodomains in all loci can share the maximal peptide sequence identity. This one-to-one correspondence of individual homeodomains in different chromosomal loci suggests the hypothesis of large-scale duplications of a single complex locus and subsequent spreading in different chromosomes. The existence of an ancestral complex locus might have predated the divergence of the arthropod/annelid and vertebrate evolutive lineages.

Amino Acid Sequence↗
PubMedDate not supplied

PEGS in children: nursing considerations.

The nursing care of children with a percutaneous endoscopic gastrostomy (PEG) means caring for the whole of the child with a PEG. Even in the highly technical and specialized field of PEG, the main themes that characterize pediatric nursing are used as a reference guide (Dall'Oglio, 1996).

Cerebral Palsy↗