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Biomedical subjects

R Stöckli

Publications and source records attributed to R Stöckli.

11 recordsLinked to original sources
PubMed2003

[Effectiveness of therapeutic interventions in obesity].

Obesity is a chronic disease resulting from various genetic factors and environmental conditions (nutrition, sedentary life-style, psychological factors). The importance of prevention and therapy of obesity is emerging because of the high prevalence of metabolic complications. The first goal of any therapy must be a stabilisation of weight, followed by a reduction of body weight. Any intervention must be long-acting. Short-acting therapies (diets) result in a regain of body weight in over 90%. The most effective therapy is an integrative concept basing on: change of nutrition by reduction of fat and carbohydrate intake (daily deficit of 500-1000 kcal). psychotherapeutic approach, targeting a long-term change of eating-behaviour and life-style, avoiding guilt feelings. encouraging physical activity. Drugs (Orlistat, Sibutramin) may be helpful in selected cases as a part of a limited treatment, they do not replace changes in lifestyle. Surgical interventions (gastric banding, gastric bypass) can be considered in morbid obesity with the presence of metabolic complications, as they are the most effective way of weight reduction.

Behavior Therapy↗
PubMed2002

[From obesity to diabetes].

The major risk factor for the development of insulin resistance and type 2 diabetes is obesity. A key role is the new understanding of adipocytes as an endocrine system. Adipocytes secrete numerous substances that contribute to peripheral insulin resistance, including adiponectin, resistin, TNF-alpha and interleukin 6. There is also a role of free fatty acids by blocking directly intracellular metabolism of glucose and by their lipotoxicity. The pre-receptor metabolism of cortisol may be enhanced in visceral adipose tissue by activation of 11 beta-hydroxysteroid dehydrogenase type 1. The new class of thiazolidinediones (glitazones), binding to the peroxisome proliferator activated receptor (PPAR-gamma) lowers the levels of resistin and increases adiponectin, resulting in an improvement of glucose homeostasis. However, the first step to avoid insulin resistance should be an attempt to reduce body weight and to increase physical activity. These are successful means to avoid the development of type 2 diabetes from prediabetic states, as shown recently in 3 independent intervention trials.

Adipose Tissue↗
PubMed2001

[Lymphadenopathy].

Lymphadenopathy is a very common problem that affects patients of all ages. Differential diagnosis is extensive, in general lymph nodes that have been present for longer than 1 month and measure more than 1 x 1 cm should be considered for further examinations, including laboratory testing and biopsy for histological and microbiological examinations.

Adult↗
PubMed1997

[What is your diagnosis? Iron deficiency anemia due to intestinal blood loss].

Iron lack anemia due to chronic blood loss was diagnosed in a 12 year old dog based on typical hematological abnormalities including moderate regenerative anemia (Hct 21%) and microcytosis (MCV 39 fl). Clinical abnormalities included weakness and episodic vomiting. Chronic occult blood loss in adult dogs most commonly occurs in the gastrointestinal tract associated with ulcus or neoplasia. Possible diagnostic steps include radiographs, abdominal ultrasound, gastroduodenoscopy and exploratory laparotomy. In the dog of this report gastric and duodenal adenocarcinomata were found during necropsy confirming the clinical suspicion of a bleeding gastrointestinal malignancy.

Adenocarcinoma↗
PubMed1986

[Not Available].

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Dental Equipment↗