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Biomedical subjects

R Stegmann

Publications and source records attributed to R Stegmann.

26 records · Page 2Linked to original sources
PubMed1986

Use of sodium hyaluronate in severe penetrating ocular trauma.

This study describes the surgical treatment and eventual outcome of 15 cases of anterior-segment penetrating ocular trauma that would be classically considered as having a poor prognosis. Signs of poor prognosis included: corneal lacerations, complicated by signs of infection ranging from infiltration to necrotic digestion; large scleral lacerations, with ciliary body or choroidal prolapse; and an exaggerated inflammatory response to the trauma. Treatment included careful microsurgical techniques, vitrectomy (when necessary), use of antibiotics and anti-inflammatory agents, and the liberal use of sodium hyaluronate to break fibrin adhesions and maintain the chamber at the close of surgery. Such treatment resulted in no enucleations, an average best corrected visual acuity of 20/80, an average normal angle of 314 degrees, and 13 cases of normal intraocular pressure without medication.

Combined Modality Therapy↗
PubMed1982

Extracapsular cataract extraction with hyaluronate sodium.

Extracapsular cataract extraction may result in a lower incidence of cystoid macular edema, but it may be a different operation from a technical standpoint. We tried a method using 1% hyaluronate sodium (Healon) as the irrigating vehicle during the procedure. The high viscosity of hyaluronate prevents posterior capsule rupture and its coating effect protects the corneal endothelium from trauma. In the study 20 eyes received the extracapsular extraction using a traditional technique with balanced salt solution. Another 20 eyes received the surgery using hyaluronate. The resulting endothelial cell counts, postoperatively, showing significantly less loss of endothelial cell using hyaluronate.

Adolescent↗
PubMed1981

Use of sodium hyaluronate in human IOL implantation.

Intraocular lenses (IOLs) were implanted into each eye of 20 patients. In one eye of each patient, sodium hyaluronate [Healon] was used to maintain the anterior chamber and coat the corneal endothelium during surgery. Postoperative results were compared to the other eye of the 20 patients receiving IOL implants in the conventional way. Endothelial cell loss averaged 18% in the sodium hyaluronate treated eyes vs. a 54% endothelial cell loss in the control group.

Aged↗
PubMed1980

Use of Na-hyaluronate in auto-corneal transplantation in rabbits.

Some of the distressing results found in eyes with clear corneal transplants are secondary glaucoma due to anterior synechiae, a high degree of astigmatism, and loss of large numbers of endothelial cells. In an attempt to decrease these complications, auto corneal transplantation was performed in each eye of fifteen rabbits. Na-hyaluronate, a clear viscous solution, was instilled in one eye prior to suture closure and balanced salt solution was placed in the control eye during suture closure. During the 4-week postoperative period, it was observed that the eyes treated with Na-hyaluronate showed a statistically significant decrease in corneal edema, a lower incidence of anterior synechiae, and a decrease in astigmatism which did not meet rigid statistical significance.

Animals↗