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Biomedical subjects

R Strang

Publications and source records attributed to R Strang.

At least 73 records · Page 4Linked to original sources

An assessment of visible-light polymerizing sources.

Measurements were made of the spectral distribution of light emitted from five commercially available visible-light polymerization units. All emissions peaked between 400 and 500 nm but the 'functional' irradiance varied by a factor of 20 for the sources investigated. Timer checks revealed errors of up to 20%. Light output was plotted as a function of time and, after 60 s, varied from-15% to +38% of the initial level. The decrease in irradiance with distance from the end of the guide was such that irradiance at 20 mm was between 20% and 40% of that at 2 mm. The light distribution across the face of each light guide was investigated and significant inhomogeneities discovered. An ultraviolet light (UV) hazard assessment was performed and it was concluded that none of the light sources presented a hazard to the operator in normal use.

Chemical Phenomena↗

Further abrasion resistance and bond strength studies of fissure sealants.

As part of a laboratory evaluation, measurements of abrasion loss and tensile enamel--sealant bond strengths have been made on three visible light cured sealants (two filled, one unfilled), two chemically cured sealants (one filled and one unfilled) and an experimental sealant with alumina filler particles. A UV-cured filled sealant was used as a control. The unfilled sealants had abrasion loss approximately twice that of the filled commercial sealants. The experimental sealant, with filler content above 50%, had an abrasion loss approximately half that of the filled commercial sealants. The chemical cured sealants had bond strengths lower than the UV-cured control, while the bond strengths of the two visible light-cured filled sealants and the experimental sealant were not statistically different from either the unfilled visible light-cured sealant or from the UV-cured filled sealant.

Animals↗

Laboratory studies of visible-light cured fissure sealants: setting times and depth of polymerization.

Measurements were made, using an acoustic transmission method, of the setting times of three visible-light curing sealants (two filled, one unfilled). Five commercially available visible-light polymerizing sources were tested with each material. Only three of the light sources gave setting times not significantly different from the manufacturers' recommended times for all three materials tested. The variation in microhardness with depth of sealant was measured to study the depth of polymerization of the sealants, all of which were adequate. The filled sealants had microhardness values greater than the unfilled sealant, at all depths studied.

Chemical Phenomena↗

Theoretical of the measurement of choroidal blood flow using a radioactive inert gas clearance technique.

A mathematical model for the diffusion of krypton in ocular tissues and its removal by blood flow has been developed to explain the complex clearance pattern found experimentally in the rabbit--an animal which has predominantly a choroidal circulation. Comparison of theoretical and experimental results has shown that the initial slope of the clearance curve is a measure of choroidal blood flow for values of blood flow over 500 ml/100 g/min. The shape of the curve at later times has been shown to be attributable predominantly to the diffusion of krypton into other ocular tissues.

Animals↗

The determination of the diffusion coefficient of krypton in rabbit ocular tissue.

The validity of the inert gas clearance method for measuring choroidal blood flow has recently been demonstrated by studying the diffusion of krypton in ocular tissue. In this study the diffusion coefficients of krypton in rabbit ocular tissue were calculated from measurements of the diffusion coefficients of xenon. The mean values for the diffusion coefficients of krypton obtained in this study were 1.6 X 10(-5), 0.76 X 10(-5), 0.80 X 10(-5), and 1.2 X 10(-5) cm.2 per second for the sclera, choroid, retina, and vitreous, respectively.

Animals↗

Choroidal and cerebral blood flow in baboons measured by the external monitoring of radioactive inert gases.

Quantitative measurements of blood flow using xenon-133 to measure cerebral blood flow and krypton-85 to measure choroidal blood flow were made in 12 anesthetized baboons (Papio anubis). Analysis of the clearance curves of krypton from the eye and studies of the diffusion of krypton in the eye show that the inert gas-clearance method measures choroidal blood flow only. The mean choroidal blood flow at normocapnia in this group of baboons is 463 +/- 44 ml./100 mg./min., and the mean cerebral blood flow is 46 +/- 5 ml./100 mg./min. (mean +/- 1 S.D.).

Animals↗

The response of the choroidal and cerebral circulations to changing arterial PCO2 and acetazolamide in the baboon.

Having established control values for choroidal and cerebral blood flow in twelve baboons, the response of both circulations to changing arterial PCO2 and intravenous acetazolamide was studied. The blood flow in both circulations varied directly with the PACO2, the magnitude of the response being very similar. There was a 3.6 percent change in both choroidal and cerebral blood flow per millimeter of mercury change in PACO2. Intravenous acetazolamide (25 mg./kg.) produced an increase in flow lasting approximately 50 minutes in both cerebral and choroidal circulations.

Acetazolamide↗