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Biomedical subjects

R Sturm

Publications and source records attributed to R Sturm.

At least 109 records · Page 6Linked to original sources
PubMed1980

Neonatal necrotizing enterocolitis associated with penicillin-resistant, toxigenic Clostridium butyricum.

The cause of neonatal necrotizing enterocolitis (NEC) is unknown. An association between NEC and clostridial infection has been reported from several centers, but the organisms have not been extensively characterized. Clostridium butyricum was isolated from the peritoneal fluid and cerebrospinal fluid of a neonate with NEC. The organism was resistant to the penicillins, but sensitive to vancomycin. Toxin production was demonstrated. Although the role of clostridial toxins in the pathogenesis of NEC is unknown, clostridial toxins are well established as the causes of two other intestinal diseases (antibiotic-associated pseudomembranous colitis and pig-bel). Further investigation of the role of clostridia in the pathogenesis of NEC and of the use of oral, nonabsorbable antibiotics in the treatment of NEC is needed.

Bacterial Toxins↗
PubMed1978

Computed tomography in hydatid disease of the liver: a report on 13 cases.

Computed tomography (CT) findings in hydatid disease (echinococciasis) of the liver are described. Disease was caused by Echinococcus granulosus (n = 8) or E. alveolaris (n = 5), respectively. The CT appearance of these two types of echinococciasis is quite different; in disease caused by E. granulosus the CT appearance is pathognomonic when cysts and daughter cysts surrounded by a capsula and peripheral calcification are discernible. In addition, the extent of organ involvement can be determined prior to surgical intervention. The CT appearance of E. alveolaris lesions may be indiscernible from malignant tumors.

Calcinosis↗
PubMed1977

Human mammary cancers in nu/nu-mice. A model for testing in research and clinic.

37 (85%) of 44 human breast cancers are successfully transplanted on thymus-aplastic nu/nu-mice without adjunctive immunotherapy. 16 weeks after transplantation 4 rapidly growing tumours are showing human, female karyotypes. Subsequent investigations proved a good correlation between original tumour and transplant: histology, 3H-thymidine marking index and receptors of androgen and estorgen.

Animals↗
PubMed1976

[Treatment of primary chronic fissure-in-ano by anal dilatation versus sphincterotomy (author's transl)].

A double-blind, randomized, controlled trial in the treatment of primary chronic fissure-in-ano by digital stretching of the anal canal or by a modified lateral subcutaneous sphincterotomy is reported. Whereas there was no difference in the postoperative course of both groups, by checking 65 of 66 patients 6 months postoperatively, we found significantly more lacks of continence after stretching. There was no difference regarding recurrence rate. Pressure monitoring of the anal canal showed significantly higher values at rest in both groups before operation. No correlation between results of monitoring anal pressure and defects of anal continence has been seen. These results point out that in treatment of primary chronic fissure-in-ano the lateral subcutaneous sphincterotomy is superior to anal dilatation regarding postoperative defects of anal continence. The recurrence rate in the present study does not force to prefer one of these two methods. Manometric investigations show that the resting pressure in anal canal seems to be elevated in primary chronic fissure-in-ano.

Adult↗