[What is meant by "superovulation"?].
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Biomedical subjects
Publications and source records attributed to R Sudik.
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An account is given of present applications of interceptively acting substances. Pharmaceuticals used so far for postcoital conception (oestrogens, gestagens, and combinations of these) are suitable for single application, but their regular use is limited by side-effects. Various approaches are being taken to the development of effective interceptives for high-continuity application but with low side-effects. Antigestagens, LHRH-analogues, and immunological contraceptives seem to be among the most promising classes of substances for the above purpose. Yet, none of these substances has been developed as yet to the level of clinical applicability.
Thirty-four of 100 women who had undergone officially sanctioned irreversible contraception at the Gynaecological Department of Wismar Regional Hospital were selected at random for follow-up investigation, two-and-a-half to one year after the intervention. The following psychological tests were taken: a standardised interview based on abridged psychopathological method, Freiburg personality inventory, record of complaints according to Kasielke, and the multiple-choice vocabulary test according to Lienert. Psychiatric examination was added on the basis of a structured psychopathological record system according to Grünes and Kühne. The following results were obtained from the study: All probands exhibited positive attitudes to the method of irreversible contraception. They said they would choose the same option, if they had to were asked again. They recommended the same decision to other women. Inner conflicts because of the irreversible nature of the intervention, problems of selfvalue, and impairment of partnership relations were not reported. Nor did any of the women wish refertilisation. The gynaecological intervention did in no single case turn out as source for neurotic developments or other psychiatrically relevant symptoms. However, the possibility of neurosis must be reckoned with, as it must with any other medical intervention. This risk may be effectively encountered by due consideration of the patient's personality, clarified indication, adequate information, and therapeutic support for the patient's effort to get to grips with the psychic problem. Hence, irreversible contraception can be an alternative, also for its psychic consequences, for women above 35 to whom safe reversible contraceptives cannot be applied for whatever reasons, although they have completed their own family planning.
Historical review about puerperal infections in the last 100 years on the background of publications in the Zentralblatt für Gynäkologie. The time was divided in three parts: The time after Semmelweis (1878 to 1920), the first time of chemotherapy (1920 to 1940) and the antibiotic epoche (after 1940).
The results of a retrograde analysis of lymphographic processes in 111 patients with malign vulvar and vaginal tumours are substantiating statements concerning the importance of lymphography in diagnosing metastastic processes in lymph-nodes of the inguinal and retroperitoneal region. -- Metastases could be proved lymphographically in 24 (34%) out of 70 carcinomas of the vulva and 8 (22%) out of 37 carcinomas of the vagina. In 24% of all patients with carcinomas of the vulva there were lymph-nodes involved, in two of these cases without a simultaneous involvement of the inguinal region. With carcinomas of the vagina a lumbar involvement was found in 50% of the cases. The accuracy of lymphographic diagnosis was 79% regarding the inguinal region and 89% in the iliac region. Despite of the lower accuracy with regard to inguinal lymph-nodes lymphography exceeds findings obtained by clinical palpation in this respect. As a result of the study, the use of lymphography in case of vulvar and vaginal carcinomas of all clinical stages is considered to be profitable for diagnosing and therapy planning.
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From January 1980 to July 1981 817 pregnant women were checked up by means of an ultrasonic screening programme. Ultrasonic measurement of the BPD and of the thoracic diameter were performed in the first trimester, between 21 and 30 and 31 and 40 weeks of gestation. For evaluation was used the diagram from Prenzlau and Issel. 72 out of the 817 women delivered a child with a birthweight below the 10th centile (GDR-Standards). From these children 65 (90,3%) were antenatally detected by ultrasonography. Hence, the sensitivity of the screening programme was 90,3%. The other parameters of the screening were: specifity 97,7%, positive predictive value 79,3%, negative predictive value 95,2%, effectivity 97,1%. The prediction of intrauterine growth retardation in the screening was significantly better compared to a group of 90 growth retarded children whose mothers were only examined by sonography sporadically. The average detection rate in both ultrasonic groups was 83,3%, but in contrast the percentage of clinically detected small-for-dates infants was only 15,4%.