Biomedical subjects
Publications and source records attributed to R T Horn.
Zoonotic dermatoses in dogs and cats are an important cause of skin disease in human beings. In addition, human dermatoses may occasionally be transmitted to dogs and cats. The veterinarian and the physician form a critical "health care team" in the proper management of these disorders.
Five patients with chronic intermittent palmoplantar pustulosis were treated with intralesional injections of 3.3 to 5.0 mg/mL of triamcinolone acetonide. Prompt clearing of symptoms and lesions ensued, lasting three to six months. Despite the discomfort experienced from the injections, patients preferred this treatment modality over others. Minor side effects included hypopigmentation, cutaneous atrophy, and, in one case, exacerbation of a latent dermatophyte infection.
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Keratoacanthomas (KAs) in 14 patients were treated with 20% fluorouracil ointment, two or three times daily, for two to four weeks. All lesions responded promptly and cleared in an average period of 3.4 weeks (range, one to seven weeks). Allergic contact dermatitis to fluorouracil occurred in two patients. This treatment response suggests that topical application of fluorouracil ointment is an effective alternative to conventional methods of treating KA.
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We describe here a patient with dystrophy of all 20 nails, which has persisted for five years after the resolution of alopecia areata. We feel that the term "20-nail dystrophy" is best used to describe a clinical entity that can have several causes.