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Biomedical subjects

R T Laughlin

Publications and source records attributed to R T Laughlin.

6 recordsLinked to original sources

Osteomyelitis.

The complexities of osteomyelitis make its diagnosis and treatment challenging. Current trends emphasize early diagnosis and aggressive treatment. Imaging has improved, with nuclear scans and magnetic resonance imaging, and technique modifications have enhanced the specificity of these tests. Treatment depends on thorough debridement of necrotic bone and tissue, accurate cultures and administration of culture, and sensitivity-specific antibiotics. Antibiotic delivery has expanded to include effective oral agents and local agents mixed with polymethylmethacrylate or a biodegradable substance. Success rates in treating this disease have improved with the use of a systematic approach, making outcome more predictable.

Adult

Ring fixators for reconstruction of traumatic disorders of the foot and ankle.

External fixation methods have an accepted place in orthopedic management of problems involving the foot and ankle. Traditionally, reconstruction and correction of deformity have been managed with extensive soft-tissue release, osteotomies, and arthrodeses. Methods of external fixation have evolved dramatically over the past decade with the introduction of the techniques of Ilizarov to the Western World. This article covers ankle arthrodesis, burn scar contracture, distal tibial deformity, and fractures.

Adult

Osteomyelitis.

Osteomyelitis can be difficult to treat. Current trends emphasize early diagnosis and aggressive treatment. Imaging has improved with nuclear scans and magnetic resonance imaging, and recent modifications in technique have enhanced the specificity. Treatment depends on debridement of necrotic bone and tissue, obtaining accurate cultures, and administration of culture- and sensitivity-directed antibiotics. Antibiotic delivery has expanded to include effective oral agents and local agents mixed with polymethylmethacrylate or a biodegradable substance. Success rates in treating this disease have improved with a systematic approach, making outcome more predictable.

Chronic Disease

Late functional outcome in patients with tibia fractures covered with free muscle flaps.

The functional outcome and work capacity of patients treated with a free muscle flap to cover open grade III tibial fractures was assessed. The conditions of patients, eight with grade IIIB and six with grade IIIC isolated open tibia fractures, treated with a free muscle flap transfer less than 3 months after their injury, were retrospectively reviewed. Flap survival was 86%. Twelve of the 14 were contacted, with follow-up time averaging 7 years. Four of the 14 eventually had below-knee amputations and one of the 10 patients with a successful limb salvage died of unrelated causes. All nine surviving patients with salvaged limbs had healed fractures in an average of 15 months (range, 8-23). Six were initially infected, but drainage had stopped an average of 13.5 months after flap coverage. No wounds were draining at last follow-up observation. Those tibias that were initially infected have been drainage free for an average of 78 months. The average total hospital cost of reconstruction was $48,996.40. The functional outcome in 12 patients was assessed. Eight of the nine patients whose limbs were salvaged returned to work, six to jobs with demands similar to their preinjury occupation. Three of the four patients with limb amputations were also able to return to jobs similar to their preinjury occupation. Patients must be made aware of the expected course of reconstruction and anticipated final outcome. Despite rarely achieving normal function, returning to work is a reasonable goal.

Adult

Syme amputation in patients with severe diabetes mellitus.

Surgical results and functional outcome of 52 patients treated with Syme amputations for forefoot gangrene between 1986 and 1988 were retrospectively reviewed with reference to the predictive value of posterior tibial artery Doppler examination. Wound healing was correlated with the preoperative status of the posterior tibial artery. Functional outcome was assessed by the ability to wear a prosthesis, ambulatory capabilities, episodes of ulceration, and revision surgery. Follow-up averaged 27 months. Twenty-nine patients had a posterior tibial artery with either a triphasic waveform (N = 23) or a normal pulse (6). Twenty-six (90%) of these achieved a healed wound suitable for prosthetic wear. Twenty-three patients had monophasic flow in the posterior tibial artery. Thirteen (57%) of these achieved a healed wound. Ninety percent of the patients who achieved healed wounds were fit with a prosthesis. Functional level of ambulation was assessed in 20 patients. Eighteen were community level ambulators, 11 could walk three or more blocks, and 16 could climb stairs. Eighteen wore their prosthesis all day. These findings indicate that posterior tibial artery Doppler examination is predictive of healing in the Syme amputation performed on diabetics. Furthermore, diabetics can attain a functional level of ambulation with a Syme amputation.

Adult

Displacement of an uncemented acetabular component after dislocation of a total hip prosthesis. A case report.

Review of the literature reveals few reports of complications encountered with noncemented acetabular components; most concern problems with screw or cup placement, component wear or migration, or disassembly of modular components. No reports involving the displacement of a noncemented acetabular component were found. This is a case report of a patient in whom a noncemented acetabular component was dislodged after the closed reduction of a dislocated total hip prosthesis 4.5 weeks after surgery. In light of this case, the authors believe these reductions should be performed under general anesthesia with fluoroscopic guidance. Care must be taken at surgery to ream sufficiently and obtain proper cup fit and position. Finally, the authors recommend bicortical screw fixation to provide maximum contact and rigid fixation in the early postoperative period.

Acetabulum