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Biomedical subjects

R T Maxwell

Publications and source records attributed to R T Maxwell.

5 recordsLinked to original sources

Relapsing Salmonella enteritidis infection in a young adult male with chronic granulomatous disease.

A case of chronic Salmonella enteritidis infection in a young adult patient is reported. Following an initial enteritis with bacteraemia, the illness lasted for a 7-year period and was characterized by recurrent pyrexia, anaemia, weight loss and marked hepatosplenomegaly. Investigations revealed that the patient suffers from a mild form of chronic granulomatous disease presenting in adolescence.

Adult↗

Patients with recurrent blackouts on carbamazepine therapy.

Two cases of cardiac syncope with epileptiform features are reported. The patients had been on carbamazepine for many months with increasing frequency of attacks until sinus arrest was documented. Their symptoms disappeared completely with permanent pacemaker implantation and anticonvulsant therapy withdrawal.

Aged↗

Transtelephonic electrocardiographic monitoring for detection and treatment of cardiac arrhythmia.

Published data on the use of transtelephonic electrocardiographic monitoring for evaluation of episodic symptoms suggestive of cardiac arrhythmia are sparse and conflicting. We have reviewed the use of one such device 'Cardiomemo' on our unit over an 18 month period. The study showed that transtelephonic electrocardiographic monitoring is useful in documentation of infrequent or sporadic episodes directly related to symptoms when 24-hour ambulatory electrocardiograph monitoring is normal.

Adult↗

Thyrotoxic crisis presenting as status epilepticus.

A 30 year old male patient with thyrotoxic crisis presenting as status epilepticus is reported. The aetiology, manifestations and management of this medical emergency are discussed. The importance of prompt, vigorous and comprehensive treatment of thyrotoxic crisis is emphasized. Rapid control of hyperthyroidism as well as other supportive measures are essential if the high fatality rate is to be reduced. Comprehensive management reduces mortality from 90% to 20%.

Adult↗

Efficiency of treatment and monitoring of ablative radio iodine therapy for hyperthyroidism: a DGH centre study.

Sixty-three hyperthyroid patients received ablative dosages of radio iodine. The efficacy of this treatment and the follow-up were assessed one to two and a half years later from case records and general practitioners. Fifty-seven percent of patients were hypothyroid at six months and 65% at one year; 4.8% had failed to become euthyroid within one year; 68.2% of patients were on thyroxine at the time of survey. Two patients had not been seen by their doctor for follow-up and one patient stopped her thyroxine. Most general practitioners preferred patients to be returned to their care once thyroxine treatment was stabilised. Rapid responses and predictable outcome are important advantages of this form of therapy over established methods of management. Intentional ablation is particularly convenient in situations where clinical and biochemical follow-up may be difficult. Good communications and a computer-controlled recall system should ensure effective follow-up.

Adult↗